Gene Symbol | fem-1 |
Entrez Gene ID | 177335 |
Full Name | Sex-determining protein fem-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » fem-1 cDNA ORF clone
Gene Symbol | fem-1 |
Entrez Gene ID | 177335 |
Full Name | Sex-determining protein fem-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_068423.6 | NP_500824.1 | Sex-determining protein fem-1 |
NM_068424.4 | NP_500825.1 | Sex-determining protein fem-1 |
NM_068424.3 | NP_500825.1 | Sex-determining protein fem-1 |
NM_068423.5 | NP_500824.1 | Sex-determining protein fem-1 |
Caenorhabditis elegans (roundworm) | fem-1 | NP_500824.1 |
Mus musculus (house mouse) | Fem1c | NP_775599.1 |
Rattus norvegicus (Norway rat) | Fem1c | NP_001100402.1 |
Danio rerio (zebrafish) | fem1c | NP_937788.2 |
Xenopus tropicalis (tropical clawed frog) | fem1c | XP_002931764.1 |
Pan troglodytes (chimpanzee) | FEM1C | XP_001147155.1 |
FEM1C | XP_001084429.1 | |
Canis lupus familiaris (dog) | FEM1C | XP_538557.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003839 | XP_310397.7 |
Homo sapiens (human) | FEM1C | NP_064562.1 |
Bos taurus (cattle) | LOC541180 | NP_001094689.1 |
Gallus gallus (chicken) | FEM1C | XP_428816.3 |
Drosophila melanogaster (fruit fly) | CG6966 | NP_001097796.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Results indicate that the N-terminal domain (NTD) works in mediating the sex-determining role of FEM-1/2/3 complex.
Title: Structural insight into Caenorhabditis elegans sex-determining protein FEM-2.
maternal fem-1 transcript is required to license expression of wild-type fem-1 allele in zygotic germline; defect in zygotic fem-1 expression is heritable, suggesting gene is subject to epigenetic silencing that is prevented by maternal fem-1 transcripts
Title: Epigenetic licensing of germline gene expression by maternal RNA in C. elegans.
Fem-1 protein is a substrate-specific adaptor for a CUL-2-based ubiquitin ligase.
Title: PAR-6 levels are regulated by NOS-3 in a CUL-2 dependent manner in Caenorhabditiselegans.
Results suggest that SEL-10-mediated proteolysis of FEM-1 and FEM-3 is required for normal hermaphrodite development.
Title: The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome.
The following fem-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the fem-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343303 | |
Clone ID Related Accession (Same CDS sequence) | NM_068424.4 , NM_068424.3 | |
Accession Version | NM_068424.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Sex-determining protein fem-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_068424.3. |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500825.1 |
CDS | 96..410 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343303 | |
Clone ID Related Accession (Same CDS sequence) | NM_068424.4 , NM_068424.3 | |
Accession Version | NM_068424.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Sex-determining protein fem-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_068424.2. COMPLETENESS: incomplete on both ends. |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500825.1 |
CDS | 1..315 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343302 | |
Clone ID Related Accession (Same CDS sequence) | NM_068423.6 , NM_068423.5 | |
Accession Version | NM_068423.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1971bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Sex-determining protein fem-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_068423.5. |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500824.1 |
CDS | 137..2107 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343302 | |
Clone ID Related Accession (Same CDS sequence) | NM_068423.6 , NM_068423.5 | |
Accession Version | NM_068423.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1971bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Sex-determining protein fem-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_068423.4. COMPLETENESS: incomplete on both ends. |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500824.1 |
CDS | 1..1971 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCAA ATGGACATCA TTTTCGAACA GTAATTTATA ATGCTGCGGC GGTTGGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |