Gene Symbol | hpl-2 |
Entrez Gene ID | 176506 |
Full Name | HP1 Like (heterochromatin protein) |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » hpl-2 cDNA ORF clone
Gene Symbol | hpl-2 |
Entrez Gene ID | 176506 |
Full Name | HP1 Like (heterochromatin protein) |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001027482.2 | NP_001022653.1 | HP1 Like (heterochromatin protein) |
NM_001027483.2 | NP_001022654.1 | HP1 Like (heterochromatin protein) |
NM_001027481.4 | NP_001022652.1 | HP1 Like (heterochromatin protein) |
NM_001027482.3 | NP_001022653.1 | Chromo domain-containing protein |
NM_001027483.3 | NP_001022654.1 | Chromo domain-containing protein |
NM_001027481.5 | NP_001022652.1 | Chromo domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
At the genic level, HPL-2 preferentially associates with well-expressed genes, and loss of HPL-2 results in up-regulation of some binding targets and down-regulation of others.
Title: Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2.
Caenorhabditis elegans heterochromatin protein like-2 (HPL-2), the homolog of heterochromatin protein 1 (HP1), down-regulates the unfolded protein response in the intestine.
Title: The Caenorhabditis elegans HP1 family protein HPL-2 maintains ER homeostasis through the UPR and hormesis.
Caenorhabditis elegans H1 variant his-24, hpl-1, and hpl-2 coregulate the expression of genes linked to immune response.
Title: Novel roles of Caenorhabditis elegans heterochromatin protein HP1 and linker histone in the regulation of innate immune gene expression.
Caenorhabditis elegans HPL-2 links developmental plasticity, longevity and lipid metabolism.
Title: Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism.
The heterochromatin protein 1 family proteins HPL-1 and HPL-2 are dispensable for de novo centromerization even though arrays become strongly enriched for the heterochromatin-associated H3K9me3 modification over time.
Title: Rapid de novo centromere formation occurs independently of heterochromatin protein 1 in C. elegans embryos.
The following hpl-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hpl-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340167 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027482.2 , NM_001027482.3 | |
Accession Version | NM_001027482.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | HP1 Like (heterochromatin protein) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001027482.1. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022653.1 |
CDS | 1..906 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027482.2 |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340167 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027482.2 , NM_001027482.3 | |
Accession Version | NM_001027482.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Chromo domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001027482.2. |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022653.1 |
CDS | 14..919 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027482.3 |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340168 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027483.2 , NM_001027483.3 | |
Accession Version | NM_001027483.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | HP1 Like (heterochromatin protein) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001027483.1. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022654.1 |
CDS | 1..912 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027483.2 |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340168 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027483.2 , NM_001027483.3 | |
Accession Version | NM_001027483.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Chromo domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001027483.2. |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022654.1 |
CDS | 12..923 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027483.3 |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340335 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027481.4 , NM_001027481.5 | |
Accession Version | NM_001027481.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | HP1 Like (heterochromatin protein) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001027481.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022652.1 |
CDS | 1..528 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027481.4 |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340335 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027481.4 , NM_001027481.5 | |
Accession Version | NM_001027481.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Chromo domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001027481.4. |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022652.1 |
CDS | 12..539 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027481.5 |
1 | ATGTCGAGCA AATCAACAAA GCGAGCAAAA ATCGAAGATC CGAAGGACAA CGTGTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |