| Gene Symbol | zyg-11 |
| Entrez Gene ID | 174284 |
| Full Name | Early embryogenesis protein zyg-11 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » zyg-11 cDNA ORF clone
| Gene Symbol | zyg-11 |
| Entrez Gene ID | 174284 |
| Full Name | Early embryogenesis protein zyg-11 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_063276.5 | NP_495677.1 | Early embryogenesis protein zyg-11 |
| NM_063276.4 | NP_495677.1 | Early embryogenesis protein zyg-11 |
| Pan troglodytes (chimpanzee) | ZYG11B | XP_001139134.2 |
| Mus musculus (house mouse) | Zyg11b | NP_001028806.2 |
| Gallus gallus (chicken) | ZYG11B | XP_422479.1 |
| Canis lupus familiaris (dog) | ZYG11B | XP_005629046.1 |
| Danio rerio (zebrafish) | zyg11 | NP_001035422.1 |
| Xenopus tropicalis (tropical clawed frog) | LOC100496980 | XP_002931468.1 |
| Homo sapiens (human) | ZYG11B | NP_078922.1 |
| Bos taurus (cattle) | ZYG11B | NP_001095717.1 |
| Rattus norvegicus (Norway rat) | Zyg11b | XP_342879.3 |
| Caenorhabditis elegans (roundworm) | zyg-11 | NP_495677.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the ubiquitin ligase CRL2(ZYG-11) redundantly targets the degradation of cyclin B1 in Caenorhabditis elegans and human cells.
Title: The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.
ZYG-11 interacts with CUL-2 in vivo and binds to the complex adaptor protein Elongin C using a nematode variant of the VHL-box motif.
Title: The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.
Data show that inactivation of ZYG-11 produces meiotic and polarity reversal defects similar to those observed in CUL-2 mutants, suggesting that the two proteins function in the same pathways.
Title: CUL-2 and ZYG-11 promote meiotic anaphase II and the proper placement of the anterior-posterior axis in C. elegans.
Results establish that zyg-11 and the cullin cul-2 promote the metaphase-to-anaphase transition and M phase exit at meiosis II in Caenorhabditis elegans.
Title: Zyg-11 and cul-2 regulate progression through meiosis II and polarity establishment in C. elegans.
The following zyg-11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the zyg-11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa339587 | |
| Clone ID Related Accession (Same CDS sequence) | NM_063276.5 , NM_063276.4 | |
| Accession Version | NM_063276.5 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2400bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Early embryogenesis protein zyg-11 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_063276.4. | |
1 | ATGGATCACA ATGCAGCTCT GACGACATGC AGTACCTCGG CCATTCCGAG ACTTGCGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_495677.1 |
| CDS | 13..2412 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_063276.5 |
1 | ATGGATCACA ATGCAGCTCT GACGACATGC AGTACCTCGG CCATTCCGAG ACTTGCGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa339587 | |
| Clone ID Related Accession (Same CDS sequence) | NM_063276.5 , NM_063276.4 | |
| Accession Version | NM_063276.4 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2400bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Early embryogenesis protein zyg-11 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_063276.3. COMPLETENESS: incomplete on both ends. | |
1 | ATGGATCACA ATGCAGCTCT GACGACATGC AGTACCTCGG CCATTCCGAG ACTTGCGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_495677.1 |
| CDS | 1..2400 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_063276.4 |
1 | ATGGATCACA ATGCAGCTCT GACGACATGC AGTACCTCGG CCATTCCGAG ACTTGCGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |