Gene Symbol | drh-3 |
Entrez Gene ID | 172546 |
Full Name | Dicer Related Helicase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » drh-3 cDNA ORF clone
Gene Symbol | drh-3 |
Entrez Gene ID | 172546 |
Full Name | Dicer Related Helicase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_059760.5 | NP_492161.3 | Dicer Related Helicase |
NM_059760.6 | NP_492161.3 | Dicer Related Helicase |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Results show that DRH-3 specifies 22 bp RNAs by dimerization of the helicase domain, a process mediated by ATPase activity and the N-terminal domain.
Title: Dicer-related helicase 3 forms an obligate dimer for recognizing 22G-RNA.
DRH-3 is required for the biogenesis of virus-derived secondary, but not primary, siRNAs.
Title: Homologous RIG-I-like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms.
ATPase activity of DRH-3 is stimulated only by double-stranded RNA. DRH-3 is a robust RNA-stimulated ATPase with a k(cat) value of 500/min when stimulated with short RNA duplexes.
Title: Double-stranded RNA-dependent ATPase DRH-3: insight into its role in RNAsilencing in Caenorhabditis elegans.
the drh-3 gene is essential for the development of germ-lines by maintaining chromosomal integrity in C. elegans.
Title: Dicer-related drh-3 gene functions in germ-line development by maintenance of chromosomal integrity in Caenorhabditis elegans.
The following drh-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the drh-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335298 | |
Clone ID Related Accession (Same CDS sequence) | NM_059760.5 , NM_059760.6 | |
Accession Version | NM_059760.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Dicer Related Helicase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059760.4. COMPLETENESS: incomplete on both ends. |
1 | ATGCAACCAA CTGCAATACG TTTAGAAGAT TACGACAAAT CGAAGCTTCG CCTTCCGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492161.3 |
CDS | 1..3360 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059760.5 |
1 | ATGCAACCAA CTGCAATACG TTTAGAAGAT TACGACAAAT CGAAGCTTCG CCTTCCGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335298 | |
Clone ID Related Accession (Same CDS sequence) | NM_059760.5 , NM_059760.6 | |
Accession Version | NM_059760.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Dicer Related Helicase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059760.5. |
1 | ATGCAACCAA CTGCAATACG TTTAGAAGAT TACGACAAAT CGAAGCTTCG CCTTCCGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492161.3 |
CDS | 13..3372 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059760.6 |
1 | ATGCAACCAA CTGCAATACG TTTAGAAGAT TACGACAAAT CGAAGCTTCG CCTTCCGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |