Gene Symbol | gld-1 |
Entrez Gene ID | 172532 |
Full Name | Female germline-specific tumor suppressor gld-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » gld-1 cDNA ORF clone
Gene Symbol | gld-1 |
Entrez Gene ID | 172532 |
Full Name | Female germline-specific tumor suppressor gld-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_059742.6 | NP_492143.1 | Female germline-specific tumor suppressor gld-1 |
NM_059742.7 | NP_492143.1 | Female germline-specific tumor suppressor gld-1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
glp-1 transcriptional targets lst-1 and sygl-1 are individually required for GLD-1 repression in stem cells; regulation of GLD-1 levels and pattern appears regional in the proliferative zone
Title: Germline Stem Cell Differentiation Entails Regional Control of Cell Fate Regulator GLD-1 in Caenorhabditis elegans.
Gld-1; puf-8 double-mutant germ cells begin to express the meiotic marker HIM-3, lose P granules, and form the sperm-specific membranous organelle, which are characteristics of developing spermatocytes.
Title: PUF-8 Functions Redundantly with GLD-1 to Promote the Meiotic Progression of Spermatocytes in Caenorhabditis elegans.
We examine GLD-1-binding motifs among targets conserved in C. elegans and C. briggsae and find that most, but not all, display evidence of shared ancestral binding sites.
Title: Evolutionary Dynamics of GLD-1-mRNA complexes in Caenorhabditis nematodes.
The study demonstrates that the QUA2 domain distinguishes GLD-1 from other members of the STAR family and contributes more generally to the modulation of RNA-binding affinity and specificity of KH domain containing proteins.
Title: Structural and functional implications of the QUA2 domain on RNA recognition by GLD-1.
Results show the RNA-binding protein GLD-1 in C. elegans affects multiple microRNA pathways and interacts with proteins required for microRNA function.
Title: RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans.
The following gld-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gld-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335741 | |
Clone ID Related Accession (Same CDS sequence) | NM_059742.6 , NM_059742.7 | |
Accession Version | NM_059742.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Female germline-specific tumor suppressor gld-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059742.5. COMPLETENESS: incomplete on both ends. |
1 | ATGCCGTCGT GCACCACTCC AACTTACGGT GTTTCGACCC AACTAGAAAG CCAAAGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492143.1 |
CDS | 1..1392 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059742.6 |
1 | ATGCCGTCGT GCACCACTCC AACTTACGGT GTTTCGACCC AACTAGAAAG CCAAAGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335741 | |
Clone ID Related Accession (Same CDS sequence) | NM_059742.6 , NM_059742.7 | |
Accession Version | NM_059742.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Female germline-specific tumor suppressor gld-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059742.6. |
1 | ATGCCGTCGT GCACCACTCC AACTTACGGT GTTTCGACCC AACTAGAAAG CCAAAGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492143.1 |
CDS | 36..1427 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059742.7 |
1 | ATGCCGTCGT GCACCACTCC AACTTACGGT GTTTCGACCC AACTAGAAAG CCAAAGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |