Gene Symbol | glh-1 |
Entrez Gene ID | 172414 |
Full Name | ATP-dependent RNA helicase glh-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » glh-1 cDNA ORF clone
Gene Symbol | glh-1 |
Entrez Gene ID | 172414 |
Full Name | ATP-dependent RNA helicase glh-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_059562.5 | NP_491963.1 | ATP-dependent RNA helicase glh-1 |
NM_059562.6 | NP_491963.1 | ATP-dependent RNA helicase glh-1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
we show that removal of either of two critical P-granule components, PGL-1 or GLH-1, is sufficient to cause germ cells to express UNC-119::GFP and MYO-3 and to display RNA accumulation defects similar to those observed after depletion of P granules. Our data identify P granules as critical modulators of the germline transcriptome and guardians of germ cell fate.
Title: Germ Granules Prevent Accumulation of Somatic Transcripts in the Adult
Data show that GLH-1 and its FG domain are not sufficient to form granules, but require factors like PGL-1 to nucleate the localized concentration of GLH proteins.
Title: P granules extend the nuclear pore complex environment in the C. elegans germ line.
the GLH-1/DCR-1 complex may function in the transport, deposition, or regulation of maternally-transcribed mRNAs and their associated miRNAs.
Title: C. elegans Dicer interacts with the P-granule component GLH-1 and both regulate germline RNPs.
KGB-1 and CSN-5 regulate GLH-1 levels, with GLH-1 targeted for proteosomal degradation by KGB-1 and stabilized by CSN-5.
Title: GLH-1, the C. elegans P granule protein, is controlled by the JNK KGB-1 and by the COP9 subunit CSN-5.
The following glh-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the glh-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336710 | |
Clone ID Related Accession (Same CDS sequence) | NM_059562.5 , NM_059562.6 | |
Accession Version | NM_059562.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | ATP-dependent RNA helicase glh-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059562.4. COMPLETENESS: incomplete on both ends. |
1 | ATGTCTGATG GTTGGAGTGA TAGCGAAAGT GCTGCTAAGG CCAAAACTGG ATTCGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491963.1 |
CDS | 1..2292 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059562.5 |
1 | ATGTCTGATG GTTGGAGTGA TAGCGAAAGT GCTGCTAAGG CCAAAACTGG ATTCGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336710 | |
Clone ID Related Accession (Same CDS sequence) | NM_059562.5 , NM_059562.6 | |
Accession Version | NM_059562.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | ATP-dependent RNA helicase glh-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059562.5. |
1 | ATGTCTGATG GTTGGAGTGA TAGCGAAAGT GCTGCTAAGG CCAAAACTGG ATTCGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491963.1 |
CDS | 335..2626 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059562.6 |
1 | ATGTCTGATG GTTGGAGTGA TAGCGAAAGT GCTGCTAAGG CCAAAACTGG ATTCGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |