Gene Symbol | cdk-2 |
Entrez Gene ID | 171911 |
Full Name | Cyclin-Dependent Kinase family |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » cdk-2 cDNA ORF clone
Gene Symbol | cdk-2 |
Entrez Gene ID | 171911 |
Full Name | Cyclin-Dependent Kinase family |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001026366.3 | NP_001021537.2 | Cyclin-dependent kinase 2 |
NM_001350362.1 | NP_001337286.1 | Cyclin-dependent kinase 2 |
NM_001026366.2 | NP_001021537.2 | Cyclin-dependent kinase 2 |
NM_001350362.2 | NP_001337286.1 | Protein kinase domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rapid movement through the cell cycle is supported by constitutive CYE-1/CDK-2 activity; CYE-1 and CDK-2 promote the proliferative fate as RNAi depletion of cye-1 or cdk-2 in a glp-1 partial loss-of-function mutant causes premature meiotic entry.
Title: Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the C. elegans germline.
CYE-1/CDK-2 emerges as a critical regulator of stem cell maintenance. We suggest that cyclin E and Cdk-2 may be used broadly to control developmental regulators.
Title: Cyclin E and Cdk2 control GLD-1, the mitosis/meiosis decision, and germline stem cells in Caenorhabditis elegans.
in wild-type animals, CKI-1/CKI in these cells maintained quiescence by inhibiting CYE-1/CDK-2, while sufficient CYE-1/CDK-2 remained to repress the terminal differentiation
Title: Cyclin E and CDK2 repress the terminal differentiation of quiescent cells after asymmetric division in C. elegans.
The following cdk-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cdk-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335233 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026366.3 , NM_001026366.2 | |
Accession Version | NM_001026366.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Cyclin-dependent kinase 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001026366.2. |
1 | ATGACAACCG ATATCGCTCC AGAAAGAGAC CTGCAAGGTC GCTTTTGCTC ACTCCGGCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021537.2 |
CDS | 14..1030 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026366.3 |
1 | ATGACAACCG ATATCGCTCC AGAAAGAGAC CTGCAAGGTC GCTTTTGCTC ACTCCGGCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335233 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026366.3 , NM_001026366.2 | |
Accession Version | NM_001026366.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Cyclin-dependent kinase 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Apr 13, 2017 this sequence version replaced NM_001026366.1. COMPLETENESS: incomplete on both ends. |
1 | ATGACAACCG ATATCGCTCC AGAAAGAGAC CTGCAAGGTC GCTTTTGCTC ACTCCGGCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021537.2 |
CDS | 1..1017 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026366.2 |
1 | ATGACAACCG ATATCGCTCC AGAAAGAGAC CTGCAAGGTC GCTTTTGCTC ACTCCGGCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336107 | |
Clone ID Related Accession (Same CDS sequence) | NM_001350362.1 , NM_001350362.2 | |
Accession Version | NM_001350362.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Cyclin-dependent kinase 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGTGGTCGC TGGGATGTAT ATTCTCCGAA ATTGCATCGA ATAAGCCTCT GTTTCCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001337286.1 |
CDS | 1..423 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001350362.1 |
1 | ATGTGGTCGC TGGGATGTAT ATTCTCCGAA ATTGCATCGA ATAAGCCTCT GTTTCCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336107 | |
Clone ID Related Accession (Same CDS sequence) | NM_001350362.1 , NM_001350362.2 | |
Accession Version | NM_001350362.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein kinase domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001350362.1. |
1 | ATGTGGTCGC TGGGATGTAT ATTCTCCGAA ATTGCATCGA ATAAGCCTCT GTTTCCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001337286.1 |
CDS | 625..1047 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001350362.2 |
1 | ATGTGGTCGC TGGGATGTAT ATTCTCCGAA ATTGCATCGA ATAAGCCTCT GTTTCCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |