Gene Symbol | STAT1 |
Entrez Gene ID | 510814 |
Full Name | signal transducer and activator of transcription 1, 91kDa |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » STAT1 cDNA ORF clone
Gene Symbol | STAT1 |
Entrez Gene ID | 510814 |
Full Name | signal transducer and activator of transcription 1, 91kDa |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005202573.4 | XP_005202630.1 | signal transducer and activator of transcription 1-alpha/beta isoform X1 |
XM_005202573.3 | XP_005202630.1 | signal transducer and activator of transcription 1-alpha/beta isoform X1 |
XM_005202570.4 | XP_005202627.2 | signal transducer and activator of transcription 1-alpha/beta isoform X1 |
XM_005202570.3 | XP_005202627.2 | signal transducer and activator of transcription 1-alpha/beta isoform X1 |
XM_025000682.1 | XP_024856450.1 | signal transducer and activator of transcription 1-alpha/beta isoform X2 |
XM_025000697.1 | XP_024856465.1 | signal transducer and activator of transcription 1-alpha/beta isoform X1 |
NM_001077900.1 | NP_001071368.1 | signal transducer and activator of transcription 1-alpha/beta |
Canis lupus familiaris (dog) | LOC488449 | XP_848353.1 |
Bos taurus (cattle) | STAT1 | NP_001071368.1 |
Rattus norvegicus (Norway rat) | Stat1 | NP_116001.2 |
Gallus gallus (chicken) | STAT1 | NP_001012932.1 |
Pan troglodytes (chimpanzee) | STAT1 | XP_003309418.1 |
Mus musculus (house mouse) | Stat1 | NP_001192242.1 |
Homo sapiens (human) | STAT1 | NP_009330.1 |
STAT1 | XP_002799062.1 | |
Danio rerio (zebrafish) | stat1a | NP_571555.1 |
Xenopus tropicalis (tropical clawed frog) | stat1 | NP_001072935.1 |
Analysis of STAT1 expression and biological activity reveals interferon-tau-dependent STAT1-regulated SOCS genes in the bovine endometrium.
Vitorino Carvalho A, Eozenou C, Healey GD, Forde N, Reinaud P, Chebrout M, Gall L, Rodde N, Padilla AL, Delville CG, Leveugle M, Richard C, Sheldon IM, Lonergan P, Jolivet G, Sandra O
Reproduction, fertility, and development28(4)459-74(2016 Mar)
Effects of signal transducer and activator of transcription (STAT) genes STAT1 and STAT3 genotypic combinations on fertilization and embryonic survival rates in Holstein cattle.
Khatib H, Huang W, Mikheil D, Schutzkus V, Monson RL
Journal of dairy science92(12)6186-91(2009 Dec)
Interferon-alpha signalling in bovine adrenal chromaffin cells: involvement of signal-transducer and activator of transcription 1 and 2, extracellular signal-regulated protein kinases 1/2 and serine 31 phosphorylation of tyrosine hydroxylase.
Douglas SA, Bunn SJ
Journal of neuroendocrinology21(3)200-7(2009 Mar)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Effects of the signal transducer and activator of transcription 1 (STAT1) gene on milk production traits in Holstein dairy cattle.
Cobanoglu O, Zaitoun I, Chang YM, Shook GE, Khatib H
Journal of dairy science89(11)4433-7(2006 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Report interferon-tau dependent STAT1 regulation of SOCS genes in bovine endometrium during estrus cycle and embryo implantation.
Title: Analysis of STAT1 expression and biological activity reveals interferon-tau-dependent STAT1-regulated SOCS genes in the bovine endometrium.
the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate
Title: Effects of signal transducer and activator of transcription (STAT) genes STAT1 and STAT3 genotypic combinations on fertilization and embryonic survival rates in Holstein cattle.
Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2.
Title: Interferon-alpha signalling in bovine adrenal chromaffin cells: involvement of signal-transducer and activator of transcription 1 and 2, extracellular signal-regulated protein kinases 1/2 and serine 31 phosphorylation of tyrosine hydroxylase.
Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein synthesis and fat metabolism.
Title: Effects of the signal transducer and activator of transcription 1 (STAT1) gene on milk production traits in Holstein dairy cattle.
results show for the first time that interleukin-6 (IL), in the presence of its soluble receptor (sIL-6R), induces activation of JAK1, JAK2, and STAT1/STAT3 proteins in bovine articular chondrocytes
Title: JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression.
The following STAT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa40205 | |
Clone ID Related Accession (Same CDS sequence) | NM_001077900.1 | |
Accession Version | NM_001077900.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Bos taurus(cattle) | |
Product | signal transducer and activator of transcription 1-alpha/beta | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY488117.1. On or before Nov 21, 2006 this sequence version replaced XM_864032.1, XM_872114.1, XM_872212.1, XM_872328.1, XM_588019.2, XM_872526.1, XM_872625.1, XM_872736.1, XM_872826.1, XM_872927.1. ##Evidence-Data-START## Transcript exon combination :: AY488117.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001071368.1 |
CDS | 110..2248 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001077900.1 |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa16521 | |
Clone ID Related Accession (Same CDS sequence) | XM_005202573.4 , XM_005202573.3 , XM_005202570.4 , XM_005202570.3 , XM_025000697.1 | |
Accession Version | XM_005202573.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | signal transducer and activator of transcription 1-alpha/beta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005202573.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005202630.1 |
CDS | 331..2580 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005202573.4 |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa16521 | |
Clone ID Related Accession (Same CDS sequence) | XM_005202573.4 , XM_005202573.3 , XM_005202570.4 , XM_005202570.3 , XM_025000697.1 | |
Accession Version | XM_005202573.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | signal transducer and activator of transcription 1-alpha/beta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103844.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005202573.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005202630.1 |
CDS | 316..2565 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005202573.3 |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa16521 | |
Clone ID Related Accession (Same CDS sequence) | XM_005202573.4 , XM_005202573.3 , XM_005202570.4 , XM_005202570.3 , XM_025000697.1 | |
Accession Version | XM_005202570.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | signal transducer and activator of transcription 1-alpha/beta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005202570.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005202627.2 |
CDS | 174..2423 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005202570.4 |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa16521 | |
Clone ID Related Accession (Same CDS sequence) | XM_005202573.4 , XM_005202573.3 , XM_005202570.4 , XM_005202570.3 , XM_025000697.1 | |
Accession Version | XM_005202570.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | signal transducer and activator of transcription 1-alpha/beta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103844.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005202570.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005202627.2 |
CDS | 174..2423 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005202570.3 |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa16521 | |
Clone ID Related Accession (Same CDS sequence) | XM_005202573.4 , XM_005202573.3 , XM_005202570.4 , XM_005202570.3 , XM_025000697.1 | |
Accession Version | XM_025000697.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | signal transducer and activator of transcription 1-alpha/beta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024856465.1 |
CDS | 308..2557 |
Translation |
Target ORF information:
Target ORF information:
|
XM_025000697.1 |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa227255 | |
Clone ID Related Accession (Same CDS sequence) | XM_025000682.1 | |
Accession Version | XM_025000682.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2247bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | signal transducer and activator of transcription 1-alpha/beta isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024856450.1 |
CDS | 129..2375 |
Translation |
Target ORF information:
Target ORF information:
|
XM_025000682.1 |
1 | ATGTCCCAGT GGTATGAGCT TCAGCAGCTT GAGTCCAAAT ACCTGGAGCA GGTTCACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Analysis of STAT1 expression and biological activity reveals interferon-tau-dependent STAT1-regulated SOCS genes in the bovine endometrium. |
Effects of signal transducer and activator of transcription (STAT) genes STAT1 and STAT3 genotypic combinations on fertilization and embryonic survival rates in Holstein cattle. |
Interferon-alpha signalling in bovine adrenal chromaffin cells: involvement of signal-transducer and activator of transcription 1 and 2, extracellular signal-regulated protein kinases 1/2 and serine 31 phosphorylation of tyrosine hydroxylase. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Effects of the signal transducer and activator of transcription 1 (STAT1) gene on milk production traits in Holstein dairy cattle. |