UPK2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	UPK2
Entrez Gene ID	281569
Full Name	uroplakin 2
General protein information	Preferred Names uroplakin 2 Names uroplakin-2 UP2 UPII uroplakin II
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_010812417.3	XP_010810719.1	uroplakin-2 isoform X1
XM_010812417.2	XP_010810719.1	uroplakin-2 isoform X1
NM_174214.2	NP_776639.1	uroplakin-2 precursor

Pathways from BioSystems

Homologies

	UPK2	XP_001095616.1
Rattus norvegicus (Norway rat)	Upk2	NP_001102993.1
Homo sapiens (human)	UPK2	NP_006751.1
Canis lupus familiaris (dog)	UPK2	XP_853307.1
Mus musculus (house mouse)	Upk2	NP_033502.2
Bos taurus (cattle)	UPK2	NP_776639.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.
Tu L, Sun TT, Kreibich G
Molecular biology of the cell13(12)4221-30(2002 Dec)

Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition.
Liang FX, Riedel I, Deng FM, Zhou G, Xu C, Wu XR, Kong XP, Moll R, Sun TT
The Biochemical journal355(Pt 1)13-8(2001 Apr)

Selective interactions of UPIa and UPIb, two members of the transmembrane 4 superfamily, with distinct single transmembrane-domained proteins in differentiated urothelial cells.
Wu XR, Medina JJ, Sun TT
The Journal of biological chemistry270(50)29752-9(1995 Dec)

Precursor sequence, processing, and urothelium-specific expression of a major 15-kDa protein subunit of asymmetric unit membrane.
Lin JH, Wu XR, Kreibich G, Sun TT
The Journal of biological chemistry269(3)1775-84(1994 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following UPK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UPK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa26284	NM_174214.2 Latest version!	Bos taurus uroplakin 2 (UPK2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa26284	XM_010812417.2 Latest version!	Bos taurus uroplakin 2 (UPK2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa222623	XM_010812417.3 Latest version!	Bos taurus uroplakin 2 (UPK2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UPK2 ( NM_174214.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776639.1 Bos taurus uroplakin 2 (UPK2), mRNA.

Price & Availability↑

CloneID	OBa26284
Clone ID Related Accession (Same CDS sequence)	XM_010812417.2 , NM_174214.2
Accession Version	NM_174214.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Bos taurus(cattle)
Product	uroplakin-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L20633.1. On Jun 3, 2003 this sequence version replaced NM_174214.1. ##Evidence-Data-START## Transcript exon combination :: L20633.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCATCTC CGTGGCCTGT GTGGACCTTG TCTTGGATCC TGATTCTGCT GGCTGTCCTG 
GTCCCCGGGG CTGCAGCTGA CTTCAACATC TCAAGCCTCT CTGGTCTGCT GTCCCCAGTG 
ATGACGGAAA GCCTGCTAGT TGCCTTGCCC CCATGTCACC TCACAGGGGG CAACGCCACA 
CTGACTGTCC GGAGAGCCAA TGACAGCAAA GTGGTGAGAT CTAGCTTCGT GGTGCCTCCG 
TGCCGCGGAC GCAGGGAGCT GGTGAGCGTG GTGGACAGCG GGTCTGGCTT CACGGTCACC 
CGGCTCAGTG CATACCAGGT GACAAACCTG GCACCAGGAA CCAAATACTA CATTTCCTAC 
CTCGTGACAA AGGGGGCATC CACCGAGTCC AGCAGAGAAA TCCCAATGTC CACATTTCCT 
CGAAGGAAGG CAGAATCCAT TGGGCTGGCA ATGGCCCGGA CAGGGGGCAT GGTGGTCATC 
ACGGTGCTGC TCTCGGTCGC TATGTTCCTG CTGGTTCTGG GCTTGATCAT TGCCCTAGCA 
CTGGGCGCCC GAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776639.1
CDS	113..670
Translation	MASPWPVWTLSWILILLAVLVPGAAADFNISSLSGLLSPVMTESLLVALPPCHLTGGNATLTVRRANDSKVVRSSFVVPPCRGRRELVSVVDSGSGFTVTRLSAYQVTNLAPGTKYYISYLVTKGASTESSREIPMSTFPRRKAESIGLAMARTGGMVVITVLLSVAMFLLVLGLIIALALGARK

Target ORF information:

RefSeq Version	NM_174214.2
Organism	Bos taurus(cattle)
Definition	Bos taurus uroplakin 2 (UPK2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174214.2

ORF Insert Sequence:

ATGGCATCTC CGTGGCCTGT GTGGACCTTG TCTTGGATCC TGATTCTGCT GGCTGTCCTG 
GTCCCCGGGG CTGCAGCTGA CTTCAACATC TCAAGCCTCT CTGGTCTGCT GTCCCCAGTG 
ATGACGGAAA GCCTGCTAGT TGCCTTGCCC CCATGTCACC TCACAGGGGG CAACGCCACA 
CTGACTGTCC GGAGAGCCAA TGACAGCAAA GTGGTGAGAT CTAGCTTCGT GGTGCCTCCG 
TGCCGCGGAC GCAGGGAGCT GGTGAGCGTG GTGGACAGCG GGTCTGGCTT CACGGTCACC 
CGGCTCAGTG CATACCAGGT GACAAACCTG GCACCAGGAA CCAAATACTA CATTTCCTAC 
CTCGTGACAA AGGGGGCATC CACCGAGTCC AGCAGAGAAA TCCCAATGTC CACATTTCCT 
CGAAGGAAGG CAGAATCCAT TGGGCTGGCA ATGGCCCGGA CAGGGGGCAT GGTGGTCATC 
ACGGTGCTGC TCTCGGTCGC TATGTTCCTG CTGGTTCTGG GCTTGATCAT TGCCCTAGCA 
CTGGGCGCCC GAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPK2 ( XM_010812417.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010810719.1 Bos taurus uroplakin 2 (UPK2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa26284
Clone ID Related Accession (Same CDS sequence)	XM_010812417.2 , NM_174214.2
Accession Version	XM_010812417.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	uroplakin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104409.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010812417.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATCTC CGTGGCCTGT GTGGACCTTG TCTTGGATCC TGATTCTGCT GGCTGTCCTG 
GTCCCCGGGG CTGCAGCTGA CTTCAACATC TCAAGCCTCT CTGGTCTGCT GTCCCCAGTG 
ATGACGGAAA GCCTGCTAGT TGCCTTGCCC CCATGTCACC TCACAGGGGG CAACGCCACA 
CTGACTGTCC GGAGAGCCAA TGACAGCAAA GTGGTGAGAT CTAGCTTCGT GGTGCCTCCG 
TGCCGCGGAC GCAGGGAGCT GGTGAGCGTG GTGGACAGCG GGTCTGGCTT CACGGTCACC 
CGGCTCAGTG CATACCAGGT GACAAACCTG GCACCAGGAA CCAAATACTA CATTTCCTAC 
CTCGTGACAA AGGGGGCATC CACCGAGTCC AGCAGAGAAA TCCCAATGTC CACATTTCCT 
CGAAGGAAGG CAGAATCCAT TGGGCTGGCA ATGGCCCGGA CAGGGGGCAT GGTGGTCATC 
ACGGTGCTGC TCTCGGTCGC TATGTTCCTG CTGGTTCTGG GCTTGATCAT TGCCCTAGCA 
CTGGGCGCCC GAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010810719.1
CDS	72..629
Translation	MASPWPVWTLSWILILLAVLVPGAAADFNISSLSGLLSPVMTESLLVALPPCHLTGGNATLTVRRANDSKVVRSSFVVPPCRGRRELVSVVDSGSGFTVTRLSAYQVTNLAPGTKYYISYLVTKGASTESSREIPMSTFPRRKAESIGLAMARTGGMVVITVLLSVAMFLLVLGLIIALALGARK

Target ORF information:

RefSeq Version	XM_010812417.2
Organism	Bos taurus(cattle)
Definition	Bos taurus uroplakin 2 (UPK2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010812417.2

ORF Insert Sequence:

ATGGCATCTC CGTGGCCTGT GTGGACCTTG TCTTGGATCC TGATTCTGCT GGCTGTCCTG 
GTCCCCGGGG CTGCAGCTGA CTTCAACATC TCAAGCCTCT CTGGTCTGCT GTCCCCAGTG 
ATGACGGAAA GCCTGCTAGT TGCCTTGCCC CCATGTCACC TCACAGGGGG CAACGCCACA 
CTGACTGTCC GGAGAGCCAA TGACAGCAAA GTGGTGAGAT CTAGCTTCGT GGTGCCTCCG 
TGCCGCGGAC GCAGGGAGCT GGTGAGCGTG GTGGACAGCG GGTCTGGCTT CACGGTCACC 
CGGCTCAGTG CATACCAGGT GACAAACCTG GCACCAGGAA CCAAATACTA CATTTCCTAC 
CTCGTGACAA AGGGGGCATC CACCGAGTCC AGCAGAGAAA TCCCAATGTC CACATTTCCT 
CGAAGGAAGG CAGAATCCAT TGGGCTGGCA ATGGCCCGGA CAGGGGGCAT GGTGGTCATC 
ACGGTGCTGC TCTCGGTCGC TATGTTCCTG CTGGTTCTGG GCTTGATCAT TGCCCTAGCA 
CTGGGCGCCC GAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPK2 ( XM_010812417.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010810719.1 Bos taurus uroplakin 2 (UPK2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa222623
Clone ID Related Accession (Same CDS sequence)	XM_010812417.3
Accession Version	XM_010812417.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	uroplakin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037342.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_010812417.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATCTC CGTGGCCTGT GTGGACCTTG TCTTGGATCC TGATTCTGCT GGCTGTCCTG 
GTCCCCGGGG CTGCAGCTGA CTTCAACATC TCAAGCCTCT CTGGTCTGCT GTCCCCAGTG 
ATGACGGAAA GCCTGCTAGT TGCCTTGCCC CCATGTCACC TCACAGGGGG CAACGCCACA 
CTGACTGTCC GGAGAGCCAA TGACAGCAAA GTGGTGAGAT CTAGCTTCGT GGTGCCTCCG 
TGCCGCGGAC GCAGGGAGCT GGTGAGCGTG GTGGACAGCG GGTCTGGCTT CACGGTCACC 
CGGCTCAGTG CATACCAGGT GACAAACCTG GCACCAGGAA CCAAATACTA CATTTCCTAC 
CTCGTGACAA AGGGGGCATC CACCGAGTCC AGCAGAGAAA TCCCAATGTC CACATTTCCT 
CGAAGGAAGG CAGAATCCAT TGGGCTGGCA ATGGCCCGGA CAGGGGGCAT GGTGGTCATC 
ACAGTGCTGC TCTCGGTCGC TATGTTCCTG CTGGTTCTGG GCTTGATCAT TGCCCTAGCA 
CTGGGCGCCC GAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010810719.1
CDS	74..631
Translation	MASPWPVWTLSWILILLAVLVPGAAADFNISSLSGLLSPVMTESLLVALPPCHLTGGNATLTVRRANDSKVVRSSFVVPPCRGRRELVSVVDSGSGFTVTRLSAYQVTNLAPGTKYYISYLVTKGASTESSREIPMSTFPRRKAESIGLAMARTGGMVVITVLLSVAMFLLVLGLIIALALGARK

Target ORF information:

RefSeq Version	XM_010812417.3
Organism	Bos taurus(cattle)
Definition	Bos taurus uroplakin 2 (UPK2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010812417.3

ORF Insert Sequence:

ATGGCATCTC CGTGGCCTGT GTGGACCTTG TCTTGGATCC TGATTCTGCT GGCTGTCCTG 
GTCCCCGGGG CTGCAGCTGA CTTCAACATC TCAAGCCTCT CTGGTCTGCT GTCCCCAGTG 
ATGACGGAAA GCCTGCTAGT TGCCTTGCCC CCATGTCACC TCACAGGGGG CAACGCCACA 
CTGACTGTCC GGAGAGCCAA TGACAGCAAA GTGGTGAGAT CTAGCTTCGT GGTGCCTCCG 
TGCCGCGGAC GCAGGGAGCT GGTGAGCGTG GTGGACAGCG GGTCTGGCTT CACGGTCACC 
CGGCTCAGTG CATACCAGGT GACAAACCTG GCACCAGGAA CCAAATACTA CATTTCCTAC 
CTCGTGACAA AGGGGGCATC CACCGAGTCC AGCAGAGAAA TCCCAATGTC CACATTTCCT 
CGAAGGAAGG CAGAATCCAT TGGGCTGGCA ATGGCCCGGA CAGGGGGCAT GGTGGTCATC 
ACAGTGCTGC TCTCGGTCGC TATGTTCCTG CTGGTTCTGG GCTTGATCAT TGCCCTAGCA 
CTGGGCGCCC GAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.
Molecular biology of the cell13(12)4221-30(2002 Dec)
Tu L,Sun TT,Kreibich G

Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition.
The Biochemical journal355(Pt 1)13-8(2001 Apr)
Liang FX,Riedel I,Deng FM,Zhou G,Xu C,Wu XR,Kong XP,Moll R,Sun TT

Selective interactions of UPIa and UPIb, two members of the transmembrane 4 superfamily, with distinct single transmembrane-domained proteins in differentiated urothelial cells.
The Journal of biological chemistry270(50)29752-9(1995 Dec)
Wu XR,Medina JJ,Sun TT

Precursor sequence, processing, and urothelium-specific expression of a major 15-kDa protein subunit of asymmetric unit membrane.
The Journal of biological chemistry269(3)1775-84(1994 Jan)
Lin JH,Wu XR,Kreibich G,Sun TT