Gene Symbol | SYN1 |
Entrez Gene ID | 281510 |
Full Name | synapsin I |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » SYN1 cDNA ORF clone
Gene Symbol | SYN1 |
Entrez Gene ID | 281510 |
Full Name | synapsin I |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_024987763.1 | XP_024843531.1 | synapsin-1 isoform X1 |
NM_174191.2 | NP_776616.1 | synapsin-1 |
Bos taurus (cattle) | SYN1 | NP_776616.1 |
Canis lupus familiaris (dog) | SYN1 | XP_003435552.1 |
Rattus norvegicus (Norway rat) | Syn1 | NP_062006.1 |
Danio rerio (zebrafish) | syn1 | NP_001119909.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100158514 | NP_001121423.1 |
Homo sapiens (human) | SYN1 | NP_008881.2 |
Mus musculus (house mouse) | Syn1 | NP_038708.3 |
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals.
Gioved? S, Vaccaro P, Valtorta F, Darchen F, Greengard P, Cesareni G, Benfenati F
The Journal of biological chemistry279(42)43760-8(2004 Oct)
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction.
Gioved? S, Darchen F, Valtorta F, Greengard P, Benfenati F
The Journal of biological chemistry279(42)43769-79(2004 Oct)
Phosphorylation-regulated inhibition of the Gz GTPase-activating protein activity of RGS proteins by synapsin I.
Tu Y, Nayak SK, Woodson J, Ross EM
The Journal of biological chemistry278(52)52273-81(2003 Dec)
Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin.
Sakurada K, Kato H, Nagumo H, Hiraoka H, Furuya K, Ikuhara T, Yamakita Y, Fukunaga K, Miyamoto E, Matsumura F, Matsuo YI, Naito Y, Sasaki Y
The Journal of biological chemistry277(47)45473-9(2002 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Synapsin-Rab3 interaction may participate in the regulation of synaptic vesicle trafficking within the nerve terminals.
Title: Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals.
Interacts with rab3 protein; this interaction is likely to play a major role in the modulation of neurotransmitter release.
Title: Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction.
Synapsin acts as a phosphorylation-modulated mediator of feedback regulation of Gz signaling by the synaptic machinery
Title: Phosphorylation-regulated inhibition of the Gz GTPase-activating protein activity of RGS proteins by synapsin I.
These results raise the possibility that Ser(603) on synapsin I is alternatively phosphorylated by p21-activated kinases, not only by CaMKII, in neuronal cells in response to some stimulants.
Title: Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin.
The following SYN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SYN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa238260 | |
Clone ID Related Accession (Same CDS sequence) | XM_024987763.1 | |
Accession Version | XM_024987763.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | synapsin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037357.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCAAATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024843531.1 |
CDS | 135..2147 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024987763.1 |
1 | ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCAAATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa41751 | |
Clone ID Related Accession (Same CDS sequence) | NM_174191.2 | |
Accession Version | NM_174191.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2121bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-05 | |
Organism | Bos taurus(cattle) | |
Product | synapsin-1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M27810.1. On or before Dec 7, 2011 this sequence version replaced XM_003588170.1, NM_174191.1. ##Evidence-Data-START## Transcript exon combination :: M27810.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145413, SAMN03145415 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCAAATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776616.1 |
CDS | 124..2244 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174191.2 |
1 | ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCAAATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A whole-genome assembly of the domestic cow, Bos taurus. |
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals. |
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction. |
Phosphorylation-regulated inhibition of the Gz GTPase-activating protein activity of RGS proteins by synapsin I. |
Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin. |