Syn1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Syn1
Entrez Gene ID	24949
Full Name	synapsin I
General protein information	Preferred Names synapsin I Names synapsin-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq11
Summary	may act as an anchoring protein by linking the vesicle phospholipid layer and the cytoskeleton in neuronal presynaptic terminals; may play a role in neurotransmitter release [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019133.2	NP_062006.1	synapsin-1 isoform a
NM_001110782.2	NP_001104252.1	synapsin-1 isoform b

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SYN1	NP_776616.1
Canis lupus familiaris (dog)	SYN1	XP_003435552.1
Rattus norvegicus (Norway rat)	Syn1	NP_062006.1
Danio rerio (zebrafish)	syn1	NP_001119909.1
Xenopus tropicalis (tropical clawed frog)	LOC100158514	NP_001121423.1
Homo sapiens (human)	SYN1	NP_008881.2
Mus musculus (house mouse)	Syn1	NP_038708.3

Gene Ontology
Bibliography

Related articles in PubMed

Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function.
Lee JW, Huang BX, Kwon H, Rashid MA, Kharebava G, Desai A, Patnaik S, Marugan J, Kim HY
Nature communications713123(2016 Oct)

Natural lecithin promotes neural network complexity and activity.
Latifi S, Tamayol A, Habibey R, Sabzevari R, Kahn C, Geny D, Eftekharpour E, Annabi N, Blau A, Linder M, Arab-Tehrany E
Scientific reports625777(2016 May)

The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures.
Chernigovskaya EV, Korotkov AA, Nikitina LS, Dorofeeva NA, Glazova MV
Neurological research37(12)1108-17(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SUMOylation of synapsin Ia (SynIa) at K687 is necessary for SynIa function. Replacement of endogenous SynIa with a non-SUMOylatable mutant decreases the size of the releasable vesicle pool and impairs stimulated SV exocytosis.
Title: SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation.

The synapsin 1 in the insular cortex as a part of pathophysiological process that determines predisposition of Krushinsky-Molodkina rats to audiogenic seizures.
Title: The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures.

Report behavioral testing-related changes in the expression of synapsin I and glucocorticoid receptors in standard and enriched aged Wistar rats.
Title: Behavioral testing-related changes in the expression of Synapsin I and glucocorticoid receptors in standard and enriched aged Wistar rats.

Results suggest a mechanism of A2aR modulation of neurotransmitter release in cultured cells from medulla oblongata and suggest that protein kinase A mediates this modulation of neurotransmitter release via synapsin I phosphorylation
Title: Protein kinase A mediates adenosine A2a receptor modulation of neurotransmitter release via synapsin I phosphorylation in cultured cells from medulla oblongata.

rSynI(1.0)-minCMV drives robust and neuron-specific transgene expression throughout the CNS and is therefore useful for viral vector-mediated neuron-specific gene delivery and generation of neuron-specific transgenic animals.
Title: Generation of a neurodegenerative disease mouse model using lentiviral vectors carrying an enhanced synapsin I promoter.

The following Syn1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Syn1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12742	NM_001110782.2 Latest version!	Rattus norvegicus synapsin I (Syn1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa12771	NM_019133.2 Latest version!	Rattus norvegicus synapsin I (Syn1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Syn1 ( NM_001110782.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001104252.1 Rattus norvegicus synapsin I (Syn1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa12742
Clone ID Related Accession (Same CDS sequence)	NM_001110782.2
Accession Version	NM_001110782.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2007bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Rattus norvegicus(Norway rat)
Product	synapsin-1 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FQ084192.1, M27924.1, CO401107.1, AABR07036742.1 and BG378858.1. On Sep 5, 2012 this sequence version replaced NM_001110782.1. Transcript Variant: This variant (2) uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1, which results in a frame-shift, and a shorter isoform (b) with a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M27924.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCTAATGGG 
TATATGACAG ACCTGCAGCG CCCGCAACCA CCTCCGCCGC CGCCCTCAGC CGCCAGCCCT 
GGGGCCACTC CCGGATCCGC TGCTGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCCTCTCCAG CAGCCCCTAG TCCCGGGTCC TCGGGGGGCG GTGGCTTCTT CTCCTCGCTG 
TCTAACGCGG TCAAACAGAC CACAGCAGCT GCAGCCGCCA CCTTCAGTGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAGCCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCCGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCCGTGG ACATGGAAGT TCTTCGGAAT GGGGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGCAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGGATC CCCAGTGTTA ACTCTTTGCA TTCTGTCTAC 
AACTTTTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCCA ATCATAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTAGT TGTGAAGATG GGCCACGCAC ACTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATACGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCAGGGA ACTGGAAGAC CAATACAGGC 
TCTGCTATGC TTGAGCAGAT TGCTATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CACTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGGGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCGGGATG CTTCCCCTGG CAGGGGTTCC CACAGCCAGA CTCCATCCCC AGGAGCCCTG 
CCCTTGGGCC GCCAGACCTC CCAGCAGCCT GCAGGACCTC CTGCTCAACA ACGACCCCCA 
CCCCAGGGAG GCCCTCCACA ACCAGGCCCA GGACCTCAGC GCCAGGGACC CCCGCTGCAA 
CAGCGCCCAC CCCCACAAGG CCAGCAACAT CTTTCTGGCC TTGGACCCCC AGCTGGCAGC 
CCTCTGCCCC AGCGCCTACC AAGTCCCACA GCAGCACCTC AGCAGTCCGC CTCTCAGGCC 
ACACCAATGA CCCAGGGTCA AGGCCGCCAG TCACGGCCAG TGGCAGGAGG CCCCGGAGCA 
CCTCCAGCAG CCCGCCCGCC GGCCTCCCCA TCTCCACAGC GTCAGGCAGG GCCCCCACAG 
GCTACCCGTC AGGCATCTAT CTCTGGTCCA GCTCCACCGA AGGTCTCAGG AGCCTCACCC 
GGAGGGCAGC AGCGCCAAGG CCCTCCCCAG AAACCCCCAG GCCCTGCTGG TCCCATTCGT 
CAGGCCAGCC AGGCAGGTCC CGGACCTCGC ACTGGGCCAC CCACCACACA GCAGCCCCGG 
CCCAGCGGCC CAGGTCCTGC TGGACGTCCC ACCAAACCAC AGCTGGCTCA GAAACCCAGC 
CAGGATGTGC CACCACCCAT CATTGCTGCT GCCGGGGGAC CCCCGCACCC CCAGCTCAAA 
GCCAGCCCCG CCCAGGCCCA GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001104252.1
CDS	99..2105
Translation	MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSAAASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQRDASPGRGSHSQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPMTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQASISGPAPPKVSGASPGGQQRQGPPQKPPGPAGPIRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPTKPQLAQKPSQDVPPPIIAAAGGPPHPQLKASPAQAQP

Target ORF information:

RefSeq Version	NM_001110782.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synapsin I (Syn1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110782.2

ORF Insert Sequence:

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCTAATGGG 
TATATGACAG ACCTGCAGCG CCCGCAACCA CCTCCGCCGC CGCCCTCAGC CGCCAGCCCT 
GGGGCCACTC CCGGATCCGC TGCTGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCCTCTCCAG CAGCCCCTAG TCCCGGGTCC TCGGGGGGCG GTGGCTTCTT CTCCTCGCTG 
TCTAACGCGG TCAAACAGAC CACAGCAGCT GCAGCCGCCA CCTTCAGTGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAGCCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCCGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCCGTGG ACATGGAAGT TCTTCGGAAT GGGGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGCAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGGATC CCCAGTGTTA ACTCTTTGCA TTCTGTCTAC 
AACTTTTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCCA ATCATAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTAGT TGTGAAGATG GGCCACGCAC ACTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATACGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCAGGGA ACTGGAAGAC CAATACAGGC 
TCTGCTATGC TTGAGCAGAT TGCTATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CACTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGGGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCGGGATG CTTCCCCTGG CAGGGGTTCC CACAGCCAGA CTCCATCCCC AGGAGCCCTG 
CCCTTGGGCC GCCAGACCTC CCAGCAGCCT GCAGGACCTC CTGCTCAACA ACGACCCCCA 
CCCCAGGGAG GCCCTCCACA ACCAGGCCCA GGACCTCAGC GCCAGGGACC CCCGCTGCAA 
CAGCGCCCAC CCCCACAAGG CCAGCAACAT CTTTCTGGCC TTGGACCCCC AGCTGGCAGC 
CCTCTGCCCC AGCGCCTACC AAGTCCCACA GCAGCACCTC AGCAGTCCGC CTCTCAGGCC 
ACACCAATGA CCCAGGGTCA AGGCCGCCAG TCACGGCCAG TGGCAGGAGG CCCCGGAGCA 
CCTCCAGCAG CCCGCCCGCC GGCCTCCCCA TCTCCACAGC GTCAGGCAGG GCCCCCACAG 
GCTACCCGTC AGGCATCTAT CTCTGGTCCA GCTCCACCGA AGGTCTCAGG AGCCTCACCC 
GGAGGGCAGC AGCGCCAAGG CCCTCCCCAG AAACCCCCAG GCCCTGCTGG TCCCATTCGT 
CAGGCCAGCC AGGCAGGTCC CGGACCTCGC ACTGGGCCAC CCACCACACA GCAGCCCCGG 
CCCAGCGGCC CAGGTCCTGC TGGACGTCCC ACCAAACCAC AGCTGGCTCA GAAACCCAGC 
CAGGATGTGC CACCACCCAT CATTGCTGCT GCCGGGGGAC CCCCGCACCC CCAGCTCAAA 
GCCAGCCCCG CCCAGGCCCA GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Syn1 ( NM_019133.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062006.1 Rattus norvegicus synapsin I (Syn1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa12771
Clone ID Related Accession (Same CDS sequence)	NM_019133.2
Accession Version	NM_019133.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2115bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Rattus norvegicus(Norway rat)
Product	synapsin-1 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FQ084192.1, M27812.1, CO401107.1, AABR07036742.1 and BG378858.1. On Sep 5, 2012 this sequence version replaced NM_019133.1. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M27812.1, X04655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCTAATGGG 
TATATGACAG ACCTGCAGCG CCCGCAACCA CCTCCGCCGC CGCCCTCAGC CGCCAGCCCT 
GGGGCCACTC CCGGATCCGC TGCTGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCCTCTCCAG CAGCCCCTAG TCCCGGGTCC TCGGGGGGCG GTGGCTTCTT CTCCTCGCTG 
TCTAACGCGG TCAAACAGAC CACAGCAGCT GCAGCCGCCA CCTTCAGTGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAGCCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCCGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCCGTGG ACATGGAAGT TCTTCGGAAT GGGGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGCAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGGATC CCCAGTGTTA ACTCTTTGCA TTCTGTCTAC 
AACTTTTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCCA ATCATAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTAGT TGTGAAGATG GGCCACGCAC ACTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATACGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCAGGGA ACTGGAAGAC CAATACAGGC 
TCTGCTATGC TTGAGCAGAT TGCTATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CACTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGGGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCGGGATG CTTCCCCTGG CAGGGGTTCC CACAGCCAGA CTCCATCCCC AGGAGCCCTG 
CCCTTGGGCC GCCAGACCTC CCAGCAGCCT GCAGGACCTC CTGCTCAACA ACGACCCCCA 
CCCCAGGGAG GCCCTCCACA ACCAGGCCCA GGACCTCAGC GCCAGGGACC CCCGCTGCAA 
CAGCGCCCAC CCCCACAAGG CCAGCAACAT CTTTCTGGCC TTGGACCCCC AGCTGGCAGC 
CCTCTGCCCC AGCGCCTACC AAGTCCCACA GCAGCACCTC AGCAGTCCGC CTCTCAGGCC 
ACACCAATGA CCCAGGGTCA AGGCCGCCAG TCACGGCCAG TGGCAGGAGG CCCCGGAGCA 
CCTCCAGCAG CCCGCCCGCC GGCCTCCCCA TCTCCACAGC GTCAGGCAGG GCCCCCACAG 
GCTACCCGTC AGGCATCTAT CTCTGGTCCA GCTCCACCGA AGGTCTCAGG AGCCTCACCC 
GGAGGGCAGC AGCGCCAAGG CCCTCCCCAG AAACCCCCAG GCCCTGCTGG TCCCATTCGT 
CAGGCCAGCC AGGCAGGTCC CGGACCTCGC ACTGGGCCAC CCACCACACA GCAGCCCCGG 
CCCAGCGGCC CAGGTCCTGC TGGACGTCCC ACCAAACCAC AGCTGGCTCA GAAACCCAGC 
CAGGATGTGC CACCACCCAT CATTGCTGCT GCCGGGGGAC CCCCGCACCC CCAGCTCAAC 
AAATCCCAGT CTCTGACCAA TGCCTTCAAC CTTCCAGAGC CAGCCCCGCC CAGGCCCAGC 
CTTAGCCAGG ATGAGGTGAA AGCTGAGACC ATCCGCAGCC TGAGGAAGTC TTTCGCCAGC 
CTCTTCTCCG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062006.1
CDS	99..2213
Translation	MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSAAASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQRDASPGRGSHSQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPMTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQASISGPAPPKVSGASPGGQQRQGPPQKPPGPAGPIRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPTKPQLAQKPSQDVPPPIIAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD

Target ORF information:

RefSeq Version	NM_019133.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synapsin I (Syn1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019133.2

ORF Insert Sequence:

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCTAATGGG 
TATATGACAG ACCTGCAGCG CCCGCAACCA CCTCCGCCGC CGCCCTCAGC CGCCAGCCCT 
GGGGCCACTC CCGGATCCGC TGCTGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCCTCTCCAG CAGCCCCTAG TCCCGGGTCC TCGGGGGGCG GTGGCTTCTT CTCCTCGCTG 
TCTAACGCGG TCAAACAGAC CACAGCAGCT GCAGCCGCCA CCTTCAGTGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAGCCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCCGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCCGTGG ACATGGAAGT TCTTCGGAAT GGGGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGCAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGGATC CCCAGTGTTA ACTCTTTGCA TTCTGTCTAC 
AACTTTTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCCA ATCATAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTAGT TGTGAAGATG GGCCACGCAC ACTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATACGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCAGGGA ACTGGAAGAC CAATACAGGC 
TCTGCTATGC TTGAGCAGAT TGCTATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CACTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGGGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCGGGATG CTTCCCCTGG CAGGGGTTCC CACAGCCAGA CTCCATCCCC AGGAGCCCTG 
CCCTTGGGCC GCCAGACCTC CCAGCAGCCT GCAGGACCTC CTGCTCAACA ACGACCCCCA 
CCCCAGGGAG GCCCTCCACA ACCAGGCCCA GGACCTCAGC GCCAGGGACC CCCGCTGCAA 
CAGCGCCCAC CCCCACAAGG CCAGCAACAT CTTTCTGGCC TTGGACCCCC AGCTGGCAGC 
CCTCTGCCCC AGCGCCTACC AAGTCCCACA GCAGCACCTC AGCAGTCCGC CTCTCAGGCC 
ACACCAATGA CCCAGGGTCA AGGCCGCCAG TCACGGCCAG TGGCAGGAGG CCCCGGAGCA 
CCTCCAGCAG CCCGCCCGCC GGCCTCCCCA TCTCCACAGC GTCAGGCAGG GCCCCCACAG 
GCTACCCGTC AGGCATCTAT CTCTGGTCCA GCTCCACCGA AGGTCTCAGG AGCCTCACCC 
GGAGGGCAGC AGCGCCAAGG CCCTCCCCAG AAACCCCCAG GCCCTGCTGG TCCCATTCGT 
CAGGCCAGCC AGGCAGGTCC CGGACCTCGC ACTGGGCCAC CCACCACACA GCAGCCCCGG 
CCCAGCGGCC CAGGTCCTGC TGGACGTCCC ACCAAACCAC AGCTGGCTCA GAAACCCAGC 
CAGGATGTGC CACCACCCAT CATTGCTGCT GCCGGGGGAC CCCCGCACCC CCAGCTCAAC 
AAATCCCAGT CTCTGACCAA TGCCTTCAAC CTTCCAGAGC CAGCCCCGCC CAGGCCCAGC 
CTTAGCCAGG ATGAGGTGAA AGCTGAGACC ATCCGCAGCC TGAGGAAGTC TTTCGCCAGC 
CTCTTCTCCG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function.
Nature communications713123(2016 Oct)
Lee JW,Huang BX,Kwon H,Rashid MA,Kharebava G,Desai A,Patnaik S,Marugan J,Kim HY

Natural lecithin promotes neural network complexity and activity.
Scientific reports625777(2016 May)
Latifi S,Tamayol A,Habibey R,Sabzevari R,Kahn C,Geny D,Eftekharpour E,Annabi N,Blau A,Linder M,Arab-Tehrany E

The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures.
Neurological research37(12)1108-17(2015)
Chernigovskaya EV,Korotkov AA,Nikitina LS,Dorofeeva NA,Glazova MV

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Syn1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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