SCG2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	SCG2
Entrez Gene ID	281477
Full Name	secretogranin II
General protein information	Preferred Names secretogranin II Names secretogranin-2 chromogranin-C secretogranin II (chromogranin C) sgII
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_010802392.2	XP_010800694.1	secretogranin-2 isoform X1
XM_010802392.3	XP_010800694.1	secretogranin-2 isoform X1
NM_174176.3	NP_776601.1	secretogranin-2 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Scg2	NP_073160.1
Danio rerio (zebrafish)	scg2b	NP_001071216.1
Xenopus tropicalis (tropical clawed frog)	scg2	NP_001072311.1
Homo sapiens (human)	SCG2	NP_003460.2
Pan troglodytes (chimpanzee)	SCG2	XP_001166617.1
Canis lupus familiaris (dog)	SCG2	XP_545669.1
Bos taurus (cattle)	SCG2	NP_776601.1
Mus musculus (house mouse)	Scg2	NP_033155.1
	SCG2	XP_001108599.1
Gallus gallus (chicken)	SCG2	XP_422624.3

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Presence of secretogranin II and high-capacity, low-affinity Ca2+ storage role in nucleoplasmic Ca2+ store vesicles.
Yoo SH, Chu SY, Kim KD, Huh YH
Biochemistry46(50)14663-71(2007 Dec)

PACAP stimulates the release of the secretogranin II-derived peptide EM66 from chromaffin cells.
Guillemot J, Ait-Ali D, Turquier V, Montero-Hadjadje M, Fournier A, Vaudry H, Anouar Y, Yon L
Annals of the New York Academy of Sciences1070309-12(2006 Jul)

Formation and sequence analysis of secretoneurin, a neuropeptide derived from secretogranin II, in mammalian, bird, reptile, amphibian and fish brains.
Leitner B, Schneitler C, Klocker H, Volknandt W, Zimmermann H, Winkler H, Fischer-Colbrie R
Neuroscience letters248(2)105-8(1998 May)

Sequence analysis, tissue distribution and regulation by cell depolarization, and second messengers of bovine secretogranin II (chromogranin C) mRNA.
Fischer-Colbrie R, Gutierrez J, Hsu CM, Iacangelo A, Eiden LE
The Journal of biological chemistry265(16)9208-13(1990 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show the localization of secretogranin II (SgII) in the nucleus, more specifically, in the IP3-sensitive nucleoplasmic Ca2+ store vesicles along with CGB and the IP3 receptors.
Title: Presence of secretogranin II and high-capacity, low-affinity Ca2+ storage role in nucleoplasmic Ca2+ store vesicles.

secretogranin II-derived peptide EM66 may act downstream of the trans-synaptic stimulation of the adrenal medulla by neurocrine factors
Title: PACAP stimulates the release of the secretogranin II-derived peptide EM66 from chromaffin cells.

The following SCG2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCG2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa00085	NM_174176.3 Latest version!	Bos taurus secretogranin II (SCG2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OBa45144	XM_010802392.3 Latest version!	Bos taurus secretogranin II (SCG2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
View Old Accession Versions >>
OBa45144	XM_010802392.2	Bos taurus secretogranin II (SCG2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SCG2 ( NM_174176.3 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776601.1 Bos taurus secretogranin II (SCG2), mRNA.

Price & Availability↑

CloneID	OBa00085
Clone ID Related Accession (Same CDS sequence)	NM_174176.3
Accession Version	NM_174176.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Bos taurus(cattle)
Product	secretogranin-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J05468.1. On Aug 31, 2012 this sequence version replaced NM_174176.2. ##Evidence-Data-START## Transcript exon combination :: J05468.1, BC103034.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGAAG CTAAGACTCA CTGGCTTGGA GCAGTCCTGT CTCTCATCCC TTTAATTTTC 
CTCCTCTCTG AAGCTGAAGC TGCTTCATTT CAGAGAAACC AGCTGCTTCA GAAGGAACCA 
GATCTCAGAT TGGAAAATGT CCAAAGGTTT CCCAGTCCTG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCCGACA ACAAGCTCAC AAAGAAGAAA GCAGCCCAGA CTACAACCCC 
TACCAAGGTG TTTCTGTTCC CCTTCAGCAA AAAGAAAATG GTGACTTGCC AGAAAGTTCG 
AGGGATTCCC TGAGTGAAGA TGAATGGATG AAGATAATAG CTGAAGCTTT GAGACAGGCT 
GAAAATGAGC CCCAGTCTGC CCCAAAGGAA AACAAGCCTT ATACTTTGAA TTCAGAAAAG 
AACTTTCCAA TGGACATGCC TGATGATTAT GAGACTCAGC AGTGGGCAGA GAGAAAGCTC 
AAGCACATGA GATTCCCTCC TATGTATGAA GAGAATTCCA GGGACAACCC CTTCAAACGC 
ACAAATGAAA TAGTGGAGGA ACAATATACT CCTCAAAATC TTGCTACCTT GGAATCTGTC 
TTCCAAGAGC TGGGGAAACT GACGGGACCA AACAGCCAAA AGCGTGAGAG GGCTGATGAG 
GAGCAAAAAC TTTACACAGA TGATGAAGAT GATATCTACA AGGCTAATAA CATTGCCTAT 
GAAGACGTGG TTGGGGGAGA AGATTGGAAC CCAGTAGAGG AAAAAATAGA GAGTCAAACC 
CAGGAAGAGG TAAGAGACAG CAAAGAGAAT GCAGACAAAA CTGAGCAAAT CAATGATGAA 
ATGAAGCGTT CCGGGCAGCT GGGCCTCCAA GATGAAGATC TCCGGAAAGA GAGTAAAGAC 
CAACTCTCAG ATGATGTCTC CAAAGTAATT ACCTATCTGA AAAGGTTAGT GAATGCTGCG 
GGAAGTGGGA GGTCCCAGAA TGGGCAAACC GGGGAAAGAG CAATCAGGCT CTTTGAGAAA 
CCACTTGATC CTCAATCTAT TTATCAGCTG ATTGAAATCT CTAGGAATTT ACAGATACCC 
CCTGAAGACT TGATTGACAT GCTCAAAACT GGAGAGAAGC CAGTGGAACC AGAGCAGGAA 
CTTGAGATTC CTGTTGAACC TGAAGACATC TCAGAGGTTG ACTTAGACCA TCCAGATCTG 
TTCCAAAATA AGATGCTCTC CAAGAATGGC TACCCCAAAG CACCTGGTCA TGCTGTGGCA 
GAGGCCCTAC CGGAGGGGCT CAGTGTGGAG GACATTCTAA ATCTTTTAGG GATGGAGAGT 
GCTGCAAATC CAAAGCCTCC ATATTTTCCC AATCAGTATA ACCGAGAGAA AGTTCTGTCA 
AGACTGCCCT ATGGTCCTGG AAGATCTAAA GCTAACCAGC TCCCCAAAGC TGTCTGGATG 
CCAGATGTTG AAAATAGACA GATGGCATAT GAGAACCTGA ATGACAAGGA TCAAGAATTA 
GGAGAGTACT TGGCCAGGAT GCTGGTTAAA TACCCTGAGA TCATGAATGC CAACCCAGCG 
AAGCGAGTTC CCAGTCAAGG CTCAACTGAA GATGATCGAC AGGATGAGAA CCAAATTGAG 
CAGGCCCTCA AAGAGCATTT GAGTCAACAC AGCTCTCAGG AGACTGACAA ACTGGCCTCG 
GTAAGCAAAA GGCTCCCTGT AGGGACCCCG AAGAGTGATG ATACTCCCAA CAGACCGTAC 
TTGGATGAAG ATCTGTTAGT GAAAGTGCTG GAATACCTCA ACCAAGAAAA GGCAGAAAAG 
GGAAGGGAGC ACATTGCTAA GAGAGCAATG GAAAATATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776601.1
CDS	88..1929
Translation	MAEAKTHWLGAVLSLIPLIFLLSEAEAASFQRNQLLQKEPDLRLENVQRFPSPEMIRALEYIEKLRQQAHKEESSPDYNPYQGVSVPLQQKENGDLPESSRDSLSEDEWMKIIAEALRQAENEPQSAPKENKPYTLNSEKNFPMDMPDDYETQQWAERKLKHMRFPPMYEENSRDNPFKRTNEIVEEQYTPQNLATLESVFQELGKLTGPNSQKRERADEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENADKTEQINDEMKRSGQLGLQDEDLRKESKDQLSDDVSKVITYLKRLVNAAGSGRSQNGQTGERAIRLFEKPLDPQSIYQLIEISRNLQIPPEDLIDMLKTGEKPVEPEQELEIPVEPEDISEVDLDHPDLFQNKMLSKNGYPKAPGHAVAEALPEGLSVEDILNLLGMESAANPKPPYFPNQYNREKVLSRLPYGPGRSKANQLPKAVWMPDVENRQMAYENLNDKDQELGEYLARMLVKYPEIMNANPAKRVPSQGSTEDDRQDENQIEQALKEHLSQHSSQETDKLASVSKRLPVGTPKSDDTPNRPYLDEDLLVKVLEYLNQEKAEKGREHIAKRAMENM

Target ORF information:

RefSeq Version	NM_174176.3
Organism	Bos taurus(cattle)
Definition	Bos taurus secretogranin II (SCG2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174176.3

ORF Insert Sequence:

ATGGCAGAAG CTAAGACTCA CTGGCTTGGA GCAGTCCTGT CTCTCATCCC TTTAATTTTC 
CTCCTCTCTG AAGCTGAAGC TGCTTCATTT CAGAGAAACC AGCTGCTTCA GAAGGAACCA 
GATCTCAGAT TGGAAAATGT CCAAAGGTTT CCCAGTCCTG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCCGACA ACAAGCTCAC AAAGAAGAAA GCAGCCCAGA CTACAACCCC 
TACCAAGGTG TTTCTGTTCC CCTTCAGCAA AAAGAAAATG GTGACTTGCC AGAAAGTTCG 
AGGGATTCCC TGAGTGAAGA TGAATGGATG AAGATAATAG CTGAAGCTTT GAGACAGGCT 
GAAAATGAGC CCCAGTCTGC CCCAAAGGAA AACAAGCCTT ATACTTTGAA TTCAGAAAAG 
AACTTTCCAA TGGACATGCC TGATGATTAT GAGACTCAGC AGTGGGCAGA GAGAAAGCTC 
AAGCACATGA GATTCCCTCC TATGTATGAA GAGAATTCCA GGGACAACCC CTTCAAACGC 
ACAAATGAAA TAGTGGAGGA ACAATATACT CCTCAAAATC TTGCTACCTT GGAATCTGTC 
TTCCAAGAGC TGGGGAAACT GACGGGACCA AACAGCCAAA AGCGTGAGAG GGCTGATGAG 
GAGCAAAAAC TTTACACAGA TGATGAAGAT GATATCTACA AGGCTAATAA CATTGCCTAT 
GAAGACGTGG TTGGGGGAGA AGATTGGAAC CCAGTAGAGG AAAAAATAGA GAGTCAAACC 
CAGGAAGAGG TAAGAGACAG CAAAGAGAAT GCAGACAAAA CTGAGCAAAT CAATGATGAA 
ATGAAGCGTT CCGGGCAGCT GGGCCTCCAA GATGAAGATC TCCGGAAAGA GAGTAAAGAC 
CAACTCTCAG ATGATGTCTC CAAAGTAATT ACCTATCTGA AAAGGTTAGT GAATGCTGCG 
GGAAGTGGGA GGTCCCAGAA TGGGCAAACC GGGGAAAGAG CAATCAGGCT CTTTGAGAAA 
CCACTTGATC CTCAATCTAT TTATCAGCTG ATTGAAATCT CTAGGAATTT ACAGATACCC 
CCTGAAGACT TGATTGACAT GCTCAAAACT GGAGAGAAGC CAGTGGAACC AGAGCAGGAA 
CTTGAGATTC CTGTTGAACC TGAAGACATC TCAGAGGTTG ACTTAGACCA TCCAGATCTG 
TTCCAAAATA AGATGCTCTC CAAGAATGGC TACCCCAAAG CACCTGGTCA TGCTGTGGCA 
GAGGCCCTAC CGGAGGGGCT CAGTGTGGAG GACATTCTAA ATCTTTTAGG GATGGAGAGT 
GCTGCAAATC CAAAGCCTCC ATATTTTCCC AATCAGTATA ACCGAGAGAA AGTTCTGTCA 
AGACTGCCCT ATGGTCCTGG AAGATCTAAA GCTAACCAGC TCCCCAAAGC TGTCTGGATG 
CCAGATGTTG AAAATAGACA GATGGCATAT GAGAACCTGA ATGACAAGGA TCAAGAATTA 
GGAGAGTACT TGGCCAGGAT GCTGGTTAAA TACCCTGAGA TCATGAATGC CAACCCAGCG 
AAGCGAGTTC CCAGTCAAGG CTCAACTGAA GATGATCGAC AGGATGAGAA CCAAATTGAG 
CAGGCCCTCA AAGAGCATTT GAGTCAACAC AGCTCTCAGG AGACTGACAA ACTGGCCTCG 
GTAAGCAAAA GGCTCCCTGT AGGGACCCCG AAGAGTGATG ATACTCCCAA CAGACCGTAC 
TTGGATGAAG ATCTGTTAGT GAAAGTGCTG GAATACCTCA ACCAAGAAAA GGCAGAAAAG 
GGAAGGGAGC ACATTGCTAA GAGAGCAATG GAAAATATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCG2 ( XM_010802392.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010800694.1 Bos taurus secretogranin II (SCG2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45144
Clone ID Related Accession (Same CDS sequence)	XM_010802392.2 , XM_010802392.3
Accession Version	XM_010802392.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1908bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	secretogranin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103850.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010802392.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACATAT ATATGCATGA TTGCATCTGT GATTTACACT GCTTGCTGTC AGGAAATCTT 
TCAAACATGG CAGAAGCTAA GACTCACTGG CTTGGAGCAG TCCTGTCTCT CATCCCTTTA 
ATTTTCCTCC TCTCTGAAGC TGAAGCTGCT TCATTTCAGA GAAACCAGCT GCTTCAGAAG 
GAACCAGATC TCAGATTGGA AAATGTCCAA AGGTTTCCCA GTCCTGAAAT GATCAGGGCT 
TTGGAGTACA TAGAAAAGCT CCGACAACAA GCTCACAAAG AAGAAAGCAG CCCAGACTAC 
AACCCCTACC AAGGTGTTTC TGTTCCCCTT CAGCAAAAAG AAAATGGTGA CTTGCCAGAA 
AGTTCGAGGG ATTCCCTGAG TGAAGATGAA TGGATGAAGA TAATAGCTGA AGCTTTGAGA 
CAGGCTGAAA ATGAGCCCCA GTCTGCCCCA AAGGAAAACA AGCCTTATAC TTTGAATTCA 
GAAAAGAACT TTCCAATGGA CATGCCTGAT GATTATGAGA CTCAGCAGTG GGCAGAGAGA 
AAGCTCAAGC ACATGAGATT CCCTCCTATG TATGAAGAGA ATTCCAGGGA CAACCCCTTC 
AAACGCACAA ATGAAATAGT GGAGGAACAA TATACTCCTC AAAATCTTGC TACCTTGGAA 
TCTGTCTTCC AAGAGCTGGG GAAACTGACG GGACCAAACA GCCAAAAGCG TGAGAGGGCT 
GATGAGGAGC AAAAACTTTA CACAGATGAT GAAGATGATA TCTACAAGGC TAATAACATT 
GCCTATGAAG ACGTGGTTGG GGGAGAAGAT TGGAACCCAG TAGAGGAAAA AATAGAGAGT 
CAAACCCAGG AAGAGGTAAG AGACAGCAAA GAGAATGCAG ACAAAACTGA GCAAATCAAT 
GATGAAATGA AGCGTTCCGG GCAGCTGGGC CTCCAAGATG AAGATCTCCG GAAGGAGAGT 
AAAGACCAAC TCTCAGATGA TGTCTCCAAA GTAATTACCT ATCTGAAAAG GTTAGTGAAT 
GCTGCGGGAA GTGGGAGGTC CCAGAATGGG CAAACCGGGG AAAGAGCAAT CAGGCTCTTT 
GAGAAACCAC TTGATCCTCA ATCTATTTAT CAGCTGATTG AAATCTCTAG GAATTTACAG 
ATACCCCCTG AAGACTTGAT TGACATGCTC AAAACTGGAG AGAAGCCAGT GGAACCAGAG 
CAGGAACTTG AGATTCCTGT TGAACCTGAA GACATCTCAG AGGTTGACTT AGACCATCCA 
GATCTGTTCC AAAATAAGAT GCTCTCCAAG AATGGCTACC CCAAAGCACC TGGTCATGCT 
GTGGCAGAGG CCCTATCGGA GGGGCTCAGT GTGGAGGACA TTCTAAATCT TTTAGGGATG 
GAGAGTGCTG CAAATCCAAA GCCTCCATAT TTTCCCAATC AGTATAACCG AGAGAAAGTT 
CTGTCAAGAC TGCCCTATGG TCCTGGAAGA TCTAAAGCTA ACCAGCTCCC CAAAGCTGTC 
TGGATGCCAG ATGTTGAAAA TAGACAGATG GCATATGAGA ACCTGAATGA CAAGGATCAA 
GAATTAGGAG AGTACTTGGC CAGGATGCTG GTTAAATACC CTGAGATCAT GAATGCCAAC 
CCAGCGAAGC GAGTTCCCAG TCAAGGCTCA ACTGAAGATG ATCGACAGGA TGAGAACCAA 
ATTGAGCAGG CCCTCAAAGA GCATTTGAGT CAACACAGCT CTCAGGAGAC TGACAAACTG 
GCCTCGGTAA GCAAAAGGCT CCCTGTAGGG ACCCCGAAGA GTGATGATAC TCCCAACAGA 
CCGTACTTGG ATGAAGATCT GTTAGTGAAA GTGCTGGAAT ACCTCAACCA AGAAAAGGCA 
GAAAAGGGAA GGGAGCACAT TGCTAAGAGA GCAATGGAAA ATATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010800694.1
CDS	109..2016
Translation	MYIYMHDCICDLHCLLSGNLSNMAEAKTHWLGAVLSLIPLIFLLSEAEAASFQRNQLLQKEPDLRLENVQRFPSPEMIRALEYIEKLRQQAHKEESSPDYNPYQGVSVPLQQKENGDLPESSRDSLSEDEWMKIIAEALRQAENEPQSAPKENKPYTLNSEKNFPMDMPDDYETQQWAERKLKHMRFPPMYEENSRDNPFKRTNEIVEEQYTPQNLATLESVFQELGKLTGPNSQKRERADEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENADKTEQINDEMKRSGQLGLQDEDLRKESKDQLSDDVSKVITYLKRLVNAAGSGRSQNGQTGERAIRLFEKPLDPQSIYQLIEISRNLQIPPEDLIDMLKTGEKPVEPEQELEIPVEPEDISEVDLDHPDLFQNKMLSKNGYPKAPGHAVAEALSEGLSVEDILNLLGMESAANPKPPYFPNQYNREKVLSRLPYGPGRSKANQLPKAVWMPDVENRQMAYENLNDKDQELGEYLARMLVKYPEIMNANPAKRVPSQGSTEDDRQDENQIEQALKEHLSQHSSQETDKLASVSKRLPVGTPKSDDTPNRPYLDEDLLVKVLEYLNQEKAEKGREHIAKRAMENM

Target ORF information:

RefSeq Version	XM_010802392.2
Organism	Bos taurus(cattle)
Definition	Bos taurus secretogranin II (SCG2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010802392.2

ORF Insert Sequence:

ATGTACATAT ATATGCATGA TTGCATCTGT GATTTACACT GCTTGCTGTC AGGAAATCTT 
TCAAACATGG CAGAAGCTAA GACTCACTGG CTTGGAGCAG TCCTGTCTCT CATCCCTTTA 
ATTTTCCTCC TCTCTGAAGC TGAAGCTGCT TCATTTCAGA GAAACCAGCT GCTTCAGAAG 
GAACCAGATC TCAGATTGGA AAATGTCCAA AGGTTTCCCA GTCCTGAAAT GATCAGGGCT 
TTGGAGTACA TAGAAAAGCT CCGACAACAA GCTCACAAAG AAGAAAGCAG CCCAGACTAC 
AACCCCTACC AAGGTGTTTC TGTTCCCCTT CAGCAAAAAG AAAATGGTGA CTTGCCAGAA 
AGTTCGAGGG ATTCCCTGAG TGAAGATGAA TGGATGAAGA TAATAGCTGA AGCTTTGAGA 
CAGGCTGAAA ATGAGCCCCA GTCTGCCCCA AAGGAAAACA AGCCTTATAC TTTGAATTCA 
GAAAAGAACT TTCCAATGGA CATGCCTGAT GATTATGAGA CTCAGCAGTG GGCAGAGAGA 
AAGCTCAAGC ACATGAGATT CCCTCCTATG TATGAAGAGA ATTCCAGGGA CAACCCCTTC 
AAACGCACAA ATGAAATAGT GGAGGAACAA TATACTCCTC AAAATCTTGC TACCTTGGAA 
TCTGTCTTCC AAGAGCTGGG GAAACTGACG GGACCAAACA GCCAAAAGCG TGAGAGGGCT 
GATGAGGAGC AAAAACTTTA CACAGATGAT GAAGATGATA TCTACAAGGC TAATAACATT 
GCCTATGAAG ACGTGGTTGG GGGAGAAGAT TGGAACCCAG TAGAGGAAAA AATAGAGAGT 
CAAACCCAGG AAGAGGTAAG AGACAGCAAA GAGAATGCAG ACAAAACTGA GCAAATCAAT 
GATGAAATGA AGCGTTCCGG GCAGCTGGGC CTCCAAGATG AAGATCTCCG GAAGGAGAGT 
AAAGACCAAC TCTCAGATGA TGTCTCCAAA GTAATTACCT ATCTGAAAAG GTTAGTGAAT 
GCTGCGGGAA GTGGGAGGTC CCAGAATGGG CAAACCGGGG AAAGAGCAAT CAGGCTCTTT 
GAGAAACCAC TTGATCCTCA ATCTATTTAT CAGCTGATTG AAATCTCTAG GAATTTACAG 
ATACCCCCTG AAGACTTGAT TGACATGCTC AAAACTGGAG AGAAGCCAGT GGAACCAGAG 
CAGGAACTTG AGATTCCTGT TGAACCTGAA GACATCTCAG AGGTTGACTT AGACCATCCA 
GATCTGTTCC AAAATAAGAT GCTCTCCAAG AATGGCTACC CCAAAGCACC TGGTCATGCT 
GTGGCAGAGG CCCTATCGGA GGGGCTCAGT GTGGAGGACA TTCTAAATCT TTTAGGGATG 
GAGAGTGCTG CAAATCCAAA GCCTCCATAT TTTCCCAATC AGTATAACCG AGAGAAAGTT 
CTGTCAAGAC TGCCCTATGG TCCTGGAAGA TCTAAAGCTA ACCAGCTCCC CAAAGCTGTC 
TGGATGCCAG ATGTTGAAAA TAGACAGATG GCATATGAGA ACCTGAATGA CAAGGATCAA 
GAATTAGGAG AGTACTTGGC CAGGATGCTG GTTAAATACC CTGAGATCAT GAATGCCAAC 
CCAGCGAAGC GAGTTCCCAG TCAAGGCTCA ACTGAAGATG ATCGACAGGA TGAGAACCAA 
ATTGAGCAGG CCCTCAAAGA GCATTTGAGT CAACACAGCT CTCAGGAGAC TGACAAACTG 
GCCTCGGTAA GCAAAAGGCT CCCTGTAGGG ACCCCGAAGA GTGATGATAC TCCCAACAGA 
CCGTACTTGG ATGAAGATCT GTTAGTGAAA GTGCTGGAAT ACCTCAACCA AGAAAAGGCA 
GAAAAGGGAA GGGAGCACAT TGCTAAGAGA GCAATGGAAA ATATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCG2 ( XM_010802392.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010800694.1 Bos taurus secretogranin II (SCG2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45144
Clone ID Related Accession (Same CDS sequence)	XM_010802392.2 , XM_010802392.3
Accession Version	XM_010802392.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1908bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	secretogranin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_010802392.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACATAT ATATGCATGA TTGCATCTGT GATTTACACT GCTTGCTGTC AGGAAATCTT 
TCAAACATGG CAGAAGCTAA GACTCACTGG CTTGGAGCAG TCCTGTCTCT CATCCCTTTA 
ATTTTCCTCC TCTCTGAAGC TGAAGCTGCT TCATTTCAGA GAAACCAGCT GCTTCAGAAG 
GAACCAGATC TCAGATTGGA AAATGTCCAA AGGTTTCCCA GTCCTGAAAT GATCAGGGCT 
TTGGAGTACA TAGAAAAGCT CCGACAACAA GCTCACAAAG AAGAAAGCAG CCCAGACTAC 
AACCCCTACC AAGGTGTTTC TGTTCCCCTT CAGCAAAAAG AAAATGGTGA CTTGCCAGAA 
AGTTCGAGGG ATTCCCTGAG TGAAGATGAA TGGATGAAGA TAATAGCTGA AGCTTTGAGA 
CAGGCTGAAA ATGAGCCCCA GTCTGCCCCA AAGGAAAACA AGCCTTATAC TTTGAATTCA 
GAAAAGAACT TTCCAATGGA CATGCCTGAT GATTATGAGA CTCAGCAGTG GGCAGAGAGA 
AAGCTCAAGC ACATGAGATT CCCTCCTATG TATGAAGAGA ATTCCAGGGA CAACCCCTTC 
AAACGCACAA ATGAAATAGT GGAGGAACAA TATACTCCTC AAAATCTTGC TACCTTGGAA 
TCTGTCTTCC AAGAGCTGGG GAAACTGACG GGACCAAACA GCCAAAAGCG TGAGAGGGCT 
GATGAGGAGC AAAAACTTTA CACAGATGAT GAAGATGATA TCTACAAGGC TAATAACATT 
GCCTATGAAG ACGTGGTTGG GGGAGAAGAT TGGAACCCAG TAGAGGAAAA AATAGAGAGT 
CAAACCCAGG AAGAGGTAAG AGACAGCAAA GAGAATGCAG ACAAAACTGA GCAAATCAAT 
GATGAAATGA AGCGTTCCGG GCAGCTGGGC CTCCAAGATG AAGATCTCCG GAAGGAGAGT 
AAAGACCAAC TCTCAGATGA TGTCTCCAAA GTAATTACCT ATCTGAAAAG GTTAGTGAAT 
GCTGCGGGAA GTGGGAGGTC CCAGAATGGG CAAACCGGGG AAAGAGCAAT CAGGCTCTTT 
GAGAAACCAC TTGATCCTCA ATCTATTTAT CAGCTGATTG AAATCTCTAG GAATTTACAG 
ATACCCCCTG AAGACTTGAT TGACATGCTC AAAACTGGAG AGAAGCCAGT GGAACCAGAG 
CAGGAACTTG AGATTCCTGT TGAACCTGAA GACATCTCAG AGGTTGACTT AGACCATCCA 
GATCTGTTCC AAAATAAGAT GCTCTCCAAG AATGGCTACC CCAAAGCACC TGGTCATGCT 
GTGGCAGAGG CCCTATCGGA GGGGCTCAGT GTGGAGGACA TTCTAAATCT TTTAGGGATG 
GAGAGTGCTG CAAATCCAAA GCCTCCATAT TTTCCCAATC AGTATAACCG AGAGAAAGTT 
CTGTCAAGAC TGCCCTATGG TCCTGGAAGA TCTAAAGCTA ACCAGCTCCC CAAAGCTGTC 
TGGATGCCAG ATGTTGAAAA TAGACAGATG GCATATGAGA ACCTGAATGA CAAGGATCAA 
GAATTAGGAG AGTACTTGGC CAGGATGCTG GTTAAATACC CTGAGATCAT GAATGCCAAC 
CCAGCGAAGC GAGTTCCCAG TCAAGGCTCA ACTGAAGATG ATCGACAGGA TGAGAACCAA 
ATTGAGCAGG CCCTCAAAGA GCATTTGAGT CAACACAGCT CTCAGGAGAC TGACAAACTG 
GCCTCGGTAA GCAAAAGGCT CCCTGTAGGG ACCCCGAAGA GTGATGATAC TCCCAACAGA 
CCGTACTTGG ATGAAGATCT GTTAGTGAAA GTGCTGGAAT ACCTCAACCA AGAAAAGGCA 
GAAAAGGGAA GGGAGCACAT TGCTAAGAGA GCAATGGAAA ATATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010800694.1
CDS	118..2025
Translation	MYIYMHDCICDLHCLLSGNLSNMAEAKTHWLGAVLSLIPLIFLLSEAEAASFQRNQLLQKEPDLRLENVQRFPSPEMIRALEYIEKLRQQAHKEESSPDYNPYQGVSVPLQQKENGDLPESSRDSLSEDEWMKIIAEALRQAENEPQSAPKENKPYTLNSEKNFPMDMPDDYETQQWAERKLKHMRFPPMYEENSRDNPFKRTNEIVEEQYTPQNLATLESVFQELGKLTGPNSQKRERADEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENADKTEQINDEMKRSGQLGLQDEDLRKESKDQLSDDVSKVITYLKRLVNAAGSGRSQNGQTGERAIRLFEKPLDPQSIYQLIEISRNLQIPPEDLIDMLKTGEKPVEPEQELEIPVEPEDISEVDLDHPDLFQNKMLSKNGYPKAPGHAVAEALSEGLSVEDILNLLGMESAANPKPPYFPNQYNREKVLSRLPYGPGRSKANQLPKAVWMPDVENRQMAYENLNDKDQELGEYLARMLVKYPEIMNANPAKRVPSQGSTEDDRQDENQIEQALKEHLSQHSSQETDKLASVSKRLPVGTPKSDDTPNRPYLDEDLLVKVLEYLNQEKAEKGREHIAKRAMENM

Target ORF information:

RefSeq Version	XM_010802392.3
Organism	Bos taurus(cattle)
Definition	Bos taurus secretogranin II (SCG2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010802392.3

ORF Insert Sequence:

ATGTACATAT ATATGCATGA TTGCATCTGT GATTTACACT GCTTGCTGTC AGGAAATCTT 
TCAAACATGG CAGAAGCTAA GACTCACTGG CTTGGAGCAG TCCTGTCTCT CATCCCTTTA 
ATTTTCCTCC TCTCTGAAGC TGAAGCTGCT TCATTTCAGA GAAACCAGCT GCTTCAGAAG 
GAACCAGATC TCAGATTGGA AAATGTCCAA AGGTTTCCCA GTCCTGAAAT GATCAGGGCT 
TTGGAGTACA TAGAAAAGCT CCGACAACAA GCTCACAAAG AAGAAAGCAG CCCAGACTAC 
AACCCCTACC AAGGTGTTTC TGTTCCCCTT CAGCAAAAAG AAAATGGTGA CTTGCCAGAA 
AGTTCGAGGG ATTCCCTGAG TGAAGATGAA TGGATGAAGA TAATAGCTGA AGCTTTGAGA 
CAGGCTGAAA ATGAGCCCCA GTCTGCCCCA AAGGAAAACA AGCCTTATAC TTTGAATTCA 
GAAAAGAACT TTCCAATGGA CATGCCTGAT GATTATGAGA CTCAGCAGTG GGCAGAGAGA 
AAGCTCAAGC ACATGAGATT CCCTCCTATG TATGAAGAGA ATTCCAGGGA CAACCCCTTC 
AAACGCACAA ATGAAATAGT GGAGGAACAA TATACTCCTC AAAATCTTGC TACCTTGGAA 
TCTGTCTTCC AAGAGCTGGG GAAACTGACG GGACCAAACA GCCAAAAGCG TGAGAGGGCT 
GATGAGGAGC AAAAACTTTA CACAGATGAT GAAGATGATA TCTACAAGGC TAATAACATT 
GCCTATGAAG ACGTGGTTGG GGGAGAAGAT TGGAACCCAG TAGAGGAAAA AATAGAGAGT 
CAAACCCAGG AAGAGGTAAG AGACAGCAAA GAGAATGCAG ACAAAACTGA GCAAATCAAT 
GATGAAATGA AGCGTTCCGG GCAGCTGGGC CTCCAAGATG AAGATCTCCG GAAGGAGAGT 
AAAGACCAAC TCTCAGATGA TGTCTCCAAA GTAATTACCT ATCTGAAAAG GTTAGTGAAT 
GCTGCGGGAA GTGGGAGGTC CCAGAATGGG CAAACCGGGG AAAGAGCAAT CAGGCTCTTT 
GAGAAACCAC TTGATCCTCA ATCTATTTAT CAGCTGATTG AAATCTCTAG GAATTTACAG 
ATACCCCCTG AAGACTTGAT TGACATGCTC AAAACTGGAG AGAAGCCAGT GGAACCAGAG 
CAGGAACTTG AGATTCCTGT TGAACCTGAA GACATCTCAG AGGTTGACTT AGACCATCCA 
GATCTGTTCC AAAATAAGAT GCTCTCCAAG AATGGCTACC CCAAAGCACC TGGTCATGCT 
GTGGCAGAGG CCCTATCGGA GGGGCTCAGT GTGGAGGACA TTCTAAATCT TTTAGGGATG 
GAGAGTGCTG CAAATCCAAA GCCTCCATAT TTTCCCAATC AGTATAACCG AGAGAAAGTT 
CTGTCAAGAC TGCCCTATGG TCCTGGAAGA TCTAAAGCTA ACCAGCTCCC CAAAGCTGTC 
TGGATGCCAG ATGTTGAAAA TAGACAGATG GCATATGAGA ACCTGAATGA CAAGGATCAA 
GAATTAGGAG AGTACTTGGC CAGGATGCTG GTTAAATACC CTGAGATCAT GAATGCCAAC 
CCAGCGAAGC GAGTTCCCAG TCAAGGCTCA ACTGAAGATG ATCGACAGGA TGAGAACCAA 
ATTGAGCAGG CCCTCAAAGA GCATTTGAGT CAACACAGCT CTCAGGAGAC TGACAAACTG 
GCCTCGGTAA GCAAAAGGCT CCCTGTAGGG ACCCCGAAGA GTGATGATAC TCCCAACAGA 
CCGTACTTGG ATGAAGATCT GTTAGTGAAA GTGCTGGAAT ACCTCAACCA AGAAAAGGCA 
GAAAAGGGAA GGGAGCACAT TGCTAAGAGA GCAATGGAAA ATATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Presence of secretogranin II and high-capacity, low-affinity Ca2+ storage role in nucleoplasmic Ca2+ store vesicles.
Biochemistry46(50)14663-71(2007 Dec)
Yoo SH,Chu SY,Kim KD,Huh YH

PACAP stimulates the release of the secretogranin II-derived peptide EM66 from chromaffin cells.
Annals of the New York Academy of Sciences1070309-12(2006 Jul)
Guillemot J,Ait-Ali D,Turquier V,Montero-Hadjadje M,Fournier A,Vaudry H,Anouar Y,Yon L

Formation and sequence analysis of secretoneurin, a neuropeptide derived from secretogranin II, in mammalian, bird, reptile, amphibian and fish brains.
Neuroscience letters248(2)105-8(1998 May)
Leitner B,Schneitler C,Klocker H,Volknandt W,Zimmermann H,Winkler H,Fischer-Colbrie R

Sequence analysis, tissue distribution and regulation by cell depolarization, and second messengers of bovine secretogranin II (chromogranin C) mRNA.
The Journal of biological chemistry265(16)9208-13(1990 Jun)
Fischer-Colbrie R,Gutierrez J,Hsu CM,Iacangelo A,Eiden LE

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SCG2 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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