Scg2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scg2
Entrez Gene ID	24765
Full Name	secretogranin II
Synonyms	Chcg
General protein information	Preferred Names secretogranin II Names secretogranin-2 Chromogranin C (Secretogranin II) chromogranin-C secretogranin II (chromogranin C) sgII
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q34
Summary	member of the chromogranin family of proteins that are localized to large dense core vesicles and are endoproteolytically processed to smaller neuropeptides [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006245148.3	XP_006245210.1	secretogranin-2 isoform X2
NM_022669.1	NP_073160.1	secretogranin-2 precursor
XM_008767195.2	XP_008765417.1	secretogranin-2 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Scg2	NP_073160.1
Danio rerio (zebrafish)	scg2b	NP_001071216.1
Xenopus tropicalis (tropical clawed frog)	scg2	NP_001072311.1
Homo sapiens (human)	SCG2	NP_003460.2
Pan troglodytes (chimpanzee)	SCG2	XP_001166617.1
Canis lupus familiaris (dog)	SCG2	XP_545669.1
Bos taurus (cattle)	SCG2	NP_776601.1
Mus musculus (house mouse)	Scg2	NP_033155.1
	SCG2	XP_001108599.1
Gallus gallus (chicken)	SCG2	XP_422624.3

Gene Ontology
Bibliography

Related articles in PubMed

Effect of food deprivation on the hypothalamic gene expression of the secretogranin II-derived peptide EM66 in rat.
Trebak F, Dubuc I, Picot M, Alaoui A, Leprince J, Pr?vost G, Anouar Y, Magoul R, Chartrel N
Neuroreport28(16)1049-1053(2017 Nov)

Localization of manserin, a secretogranin II-derived neuropeptide, in the oviduct of female rats.
Ida-Eto M, Nomura M, Ohkawara T, Narita N, Narita M
Acta histochemica116(3)522-6(2014 Apr)

Subtype-specific parafollicular localization of the neuropeptide manserin in the rat thyroid gland.
Ohkawara T, Oyabu A, Ida-Eto M, Tashiro Y, Narita N, Narita M
Acta histochemica115(2)190-4(2013 Mar)

Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.
R?sj? H, Stridsberg M, Florholmen G, Stensl?kken KO, Ottesen AH, Sjaastad I, Husberg C, Dahl MB, ?ie E, Louch WE, Omland T, Christensen G
PloS one7(5)e37401(2012)

Corticotropin-releasing factor binding protein enters the regulated secretory pathway in neuroendocrine cells and cortical neurons.
Blanco EH, Z??iga JP, Andr?s ME, Alvarez AR, Gysling K
Neuropeptides45(4)273-9(2011 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Manserin localizes to secretory cells in the oviduct and may be involved in stress-induced gynecological disorders.
Title: Localization of manserin, a secretogranin II-derived neuropeptide, in the oviduct of female rats.

Manserin localizes to rat thyroid follicular epithelial cells and also to some parafollicular cells
Title: Subtype-specific parafollicular localization of the neuropeptide manserin in the rat thyroid gland.

The secretogranin II fragment secretoneurin reduces ischemia/reperfusion injury in the isolated perfused rat heart.
Title: Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.

results indicate that manserin, occurring in the endocrine pancreas, may have a potential role in the endocrine system
Title: Manserin, a secretogranin II-derived peptide, distributes in the rat endocrine pancreas colocalized with islet-cell specific manner.

SgII is a critical factor for the regulation of DCG biogenesis in neuroendocrine cells
Title: Pro-hormone secretogranin II regulates dense core secretory granule biogenesis in catecholaminergic cells.

The following Scg2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scg2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06217	NM_022669.1 Latest version!	Rattus norvegicus secretogranin II (Scg2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa32333	XM_006245148.3 Latest version!	Rattus norvegicus secretogranin II (Scg2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa42952	XM_008767195.2 Latest version!	Rattus norvegicus secretogranin II (Scg2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scg2 ( NM_022669.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073160.1 Rattus norvegicus secretogranin II (Scg2), mRNA.

Price & Availability↑

CloneID	ORa06217
Clone ID Related Accession (Same CDS sequence)	NM_022669.1
Accession Version	NM_022669.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	secretogranin-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M93669.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M93669.1, CF978096.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGACTGAAT CGAAGGCTTA CCGATTTGGA GCAGTTCTGC TTCTTATCCA CTTAATTTTC 
CTTGTCCCTG GAACCGAAGC AGCTTCCTTC CAGCGAAACC AGCTGCTTCA GAAAGAACCA 
GACCTCAGAT TGGAGAATGT CCAGAAGTTT CCTAGTCCAG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCAGGCA GCAGGCCCAC AGAGAAGAAA GCAGCCCAGA CTACAATCCC 
TACCAAGGCA TCTCTGTTCC CCTTCAACTC AAAGAAAACG GAGAAGAAAG TCACTTGGCA 
GAGAGCTCAA GGGATGTCCT GAGTGAAGAC GAGTGGATGC GGATAATACT TGAGGCTTTG 
AGGCAGGCTG AAAATGAGCC GCCATCTGCC CTCAAGGAGA ACAAGCCCTA TGCCTTGAAT 
CTGGAGAAGA ACTTCCCTGT GGACACGCCT GATGACTATG AGACTCAACA ATGGCCTGAG 
AGGAAACTCA AGCACATGCG GTTCCCTCTC ATGTATGAAG AGAATTCCAG GGAAAACCCC 
TTCAAACGCA CAAACGAAAT AGTAGAAGAA CAGTACACAC CCCAAAGTCT TGCTACCCTG 
GAGTCTGTGT TCCAAGAGCT TGGGAAACTG ACAGGGCCAA GCAACCAGAA GCGTGAGAGG 
GTTGACGAGG AACAGAAGCT CTACACGGAC GATGAAGATG ACGTGTACAA GACCAACAAC 
ATTGCCTATG AAGATGTGGT CGGGGGAGAA GACTGGAGTC CTATGGAGGA GAAAATAGAG 
ACTCAAACCC AGGAAGAGGT GAGAGACAGC AAAGAGAACA CAGAAAAAAA CGAACAAATC 
AATGAAGAGA TGAAACGGTC AGGGCACTTG GGGCTCCCAG ATGAAGGTAA CCGGAAAGAG 
AGCAAAGACC AGCTCTCAGA GGACGCCTCC AAGGTCATCA CCTACTTGAG AAGGTTAGTG 
AATGCTGTGG GCAGTGGGAG GTCCCAGAGT GGGCAAAACG GGGACAGGGC AGCCAGGCTT 
CTTGAGAGGC CCCTTGATTC TCAGTCTATT TATCAGCTGA TTGAAATCTC CAGGAATTTG 
CAGATACCCC CTGAAGACTT AATTGAGATG CTCAAAGCTG GGGAGAAACC AAATGGGTTG 
GTGGAGCCCG AGCAGGATCT GGAGCTTGCT GTTGACCTAG ATGACATCCC GGAAGCTGAC 
ATAGACCGCC CAGACATGTT TCAAAGTAAG ACGCTCTCCA AGGGTGGGTA TCCCAAGGCA 
CCTGGTCGAG GTATGATGGA GGCCTTGCCA GATGGCCTCA GTGTTGAAGA CATTTTAAAT 
GTTTTAGGGA TGGAGAATGT AGCAAATCAG AAGTCCCCAT ATTTCCCCAA CCAATACAGC 
CGAGACAAGG CTCTGCTGAG GCTTCCTTAT GGTCCTGGGA AATCTAGAGC CAACCAGATT 
CCCAAAGTAG CCTGGATCCC AGACGTTGAA AGCAGACAAG CCCCCTATGA CAATCTGAAT 
GATAAGGACC AAGAATTGGG AGAGTACTTA GCCAGGATGC TAGTTAAGTA CCCTGAGCTC 
ATGAATACCA ACCAGCTGAA GAGAGTGCCC AGCCCAGGCT CCTCAGAAGA TGACCTCCAA 
GAAGAAGAGC AGCTCGAGCA GGCCATCAAG GAGCATCTGG GTCAAGGAAG CTCCCAGGAA 
ATGGAGAAAC TGGCCAAGGT GAGCAAAAGG ATCCCTGCAG GATCCCTGAA GAATGAGGAT 
ACCCCAAATA GACAGTACCT GGATGAAGAT ATGCTCCTGA AAGTGCTAGA GTATCTCAAT 
CAAGAACAGG CAGAGCAGGG AAGGGAACAT CTTGCCAAAC GGGCCATGGA AAACATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073160.1
CDS	31..1890
Translation	MTESKAYRFGAVLLLIHLIFLVPGTEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIEKLRQQAHREESSPDYNPYQGISVPLQLKENGEESHLAESSRDVLSEDEWMRIILEALRQAENEPPSALKENKPYALNLEKNFPVDTPDDYETQQWPERKLKHMRFPLMYEENSRENPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPSNQKRERVDEEQKLYTDDEDDVYKTNNIAYEDVVGGEDWSPMEEKIETQTQEEVRDSKENTEKNEQINEEMKRSGHLGLPDEGNRKESKDQLSEDASKVITYLRRLVNAVGSGRSQSGQNGDRAARLLERPLDSQSIYQLIEISRNLQIPPEDLIEMLKAGEKPNGLVEPEQDLELAVDLDDIPEADIDRPDMFQSKTLSKGGYPKAPGRGMMEALPDGLSVEDILNVLGMENVANQKSPYFPNQYSRDKALLRLPYGPGKSRANQIPKVAWIPDVESRQAPYDNLNDKDQELGEYLARMLVKYPELMNTNQLKRVPSPGSSEDDLQEEEQLEQAIKEHLGQGSSQEMEKLAKVSKRIPAGSLKNEDTPNRQYLDEDMLLKVLEYLNQEQAEQGREHLAKRAMENM

Target ORF information:

RefSeq Version	NM_022669.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus secretogranin II (Scg2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022669.1

ORF Insert Sequence:

ATGACTGAAT CGAAGGCTTA CCGATTTGGA GCAGTTCTGC TTCTTATCCA CTTAATTTTC 
CTTGTCCCTG GAACCGAAGC AGCTTCCTTC CAGCGAAACC AGCTGCTTCA GAAAGAACCA 
GACCTCAGAT TGGAGAATGT CCAGAAGTTT CCTAGTCCAG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCAGGCA GCAGGCCCAC AGAGAAGAAA GCAGCCCAGA CTACAATCCC 
TACCAAGGCA TCTCTGTTCC CCTTCAACTC AAAGAAAACG GAGAAGAAAG TCACTTGGCA 
GAGAGCTCAA GGGATGTCCT GAGTGAAGAC GAGTGGATGC GGATAATACT TGAGGCTTTG 
AGGCAGGCTG AAAATGAGCC GCCATCTGCC CTCAAGGAGA ACAAGCCCTA TGCCTTGAAT 
CTGGAGAAGA ACTTCCCTGT GGACACGCCT GATGACTATG AGACTCAACA ATGGCCTGAG 
AGGAAACTCA AGCACATGCG GTTCCCTCTC ATGTATGAAG AGAATTCCAG GGAAAACCCC 
TTCAAACGCA CAAACGAAAT AGTAGAAGAA CAGTACACAC CCCAAAGTCT TGCTACCCTG 
GAGTCTGTGT TCCAAGAGCT TGGGAAACTG ACAGGGCCAA GCAACCAGAA GCGTGAGAGG 
GTTGACGAGG AACAGAAGCT CTACACGGAC GATGAAGATG ACGTGTACAA GACCAACAAC 
ATTGCCTATG AAGATGTGGT CGGGGGAGAA GACTGGAGTC CTATGGAGGA GAAAATAGAG 
ACTCAAACCC AGGAAGAGGT GAGAGACAGC AAAGAGAACA CAGAAAAAAA CGAACAAATC 
AATGAAGAGA TGAAACGGTC AGGGCACTTG GGGCTCCCAG ATGAAGGTAA CCGGAAAGAG 
AGCAAAGACC AGCTCTCAGA GGACGCCTCC AAGGTCATCA CCTACTTGAG AAGGTTAGTG 
AATGCTGTGG GCAGTGGGAG GTCCCAGAGT GGGCAAAACG GGGACAGGGC AGCCAGGCTT 
CTTGAGAGGC CCCTTGATTC TCAGTCTATT TATCAGCTGA TTGAAATCTC CAGGAATTTG 
CAGATACCCC CTGAAGACTT AATTGAGATG CTCAAAGCTG GGGAGAAACC AAATGGGTTG 
GTGGAGCCCG AGCAGGATCT GGAGCTTGCT GTTGACCTAG ATGACATCCC GGAAGCTGAC 
ATAGACCGCC CAGACATGTT TCAAAGTAAG ACGCTCTCCA AGGGTGGGTA TCCCAAGGCA 
CCTGGTCGAG GTATGATGGA GGCCTTGCCA GATGGCCTCA GTGTTGAAGA CATTTTAAAT 
GTTTTAGGGA TGGAGAATGT AGCAAATCAG AAGTCCCCAT ATTTCCCCAA CCAATACAGC 
CGAGACAAGG CTCTGCTGAG GCTTCCTTAT GGTCCTGGGA AATCTAGAGC CAACCAGATT 
CCCAAAGTAG CCTGGATCCC AGACGTTGAA AGCAGACAAG CCCCCTATGA CAATCTGAAT 
GATAAGGACC AAGAATTGGG AGAGTACTTA GCCAGGATGC TAGTTAAGTA CCCTGAGCTC 
ATGAATACCA ACCAGCTGAA GAGAGTGCCC AGCCCAGGCT CCTCAGAAGA TGACCTCCAA 
GAAGAAGAGC AGCTCGAGCA GGCCATCAAG GAGCATCTGG GTCAAGGAAG CTCCCAGGAA 
ATGGAGAAAC TGGCCAAGGT GAGCAAAAGG ATCCCTGCAG GATCCCTGAA GAATGAGGAT 
ACCCCAAATA GACAGTACCT GGATGAAGAT ATGCTCCTGA AAGTGCTAGA GTATCTCAAT 
CAAGAACAGG CAGAGCAGGG AAGGGAACAT CTTGCCAAAC GGGCCATGGA AAACATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scg2 ( XM_006245148.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245210.1 Rattus norvegicus secretogranin II (Scg2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa32333
Clone ID Related Accession (Same CDS sequence)	XM_006245148.3
Accession Version	XM_006245148.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	secretogranin-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245148.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGAAT CGAAGGCTTA CCGATTTGGA GCAGTTCTGC TTCTTATCCA CTTAATTTTC 
CTTGTCCCTG GAACCGAAGC AGCTTCCTTC CAGCGAAACC AGCTGCTTCA GAAAGAACCA 
GACCTCAGAT TGGAGAATGT CCAGAAGTTT CCTAGTCCAG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCAGGCA GCAGGCCCAC AGAGAAGAAA GCAGCCCAGA CTACAATCCC 
TACCAAGGCA TCTCTGTTCC CCTTCAACTC AAAGAAAACG GAGAAGAAAG TCACTTGGCA 
GAGAGCTCAA GGGATGTCTT GAGTGAAGAC GAGTGGATGC GGATAATACT TGAGGCTTTG 
AGGCAGGCTG AAAATGAGCC GCCATCTGCC CTCAAGGAGA ACAAGCCCTA TGCCTTGAAT 
CTGGAGAAGA ACTTCCCTGT GGACACGCCT GATGACTATG AGACTCAACA ATGGCCTGAG 
AGGAAACTCA AGCACATGCG GTTCCCTCTC ATGTATGAAG AGAATTCCAG GGAAAACCCC 
TTCAAACGCA CAAACGAAAT AGTAGAAGAA CAGTACACAC CCCAAAGTCT TGCTACCCTG 
GAGTCTGTGT TCCAAGAGCT TGGGAAACTG ACAGGGCCAA GCAACCAGAA GCGTGAGAGG 
GTTGACGAGG AACAGAAGCT CTACACGGAC GATGAAGATG ACGTGTACAA GACCAACAAC 
ATTGCCTATG AAGATGTGGT CGGGGGAGAA GACTGGAGTC CTATGGAGGA GAAAATAGAG 
ACTCAAACCC AGGAAGAGGT GAGAGACAGC AAAGAGAACA CAGAAAAAAA CGAACAAATC 
AATGAAGAGA TGAAACGGTC AGGGCACTTG GGGCTCCCAG ATGAAGGTAA CCGGAAAGAG 
AGCAAAGACC AGCTCTCAGA GGACGCCTCC AAGGTCATCA CCTACTTGAG AAGGAATTTG 
CAGATACCCC CTGAAGACTT AATTGAGATG CTCAAAGCTG GGGAGAAACC AAATGGGTTG 
GTGGAGCCCG AGCAGGATCT GGAGCTTGCT GTTGACCTAG ATGACATCCC GGAAGCTGAC 
ATAGACCGCC CAGACATGTT TCAAAGTAAG ACGCTCTCCA AGGGTGGGTA TCCCAAGGCA 
CCTGGTCGAG GTATGATGGA GGCCTTGCCA GATGGCCTCA GTGTTGAAGA CATTTTAAAT 
GTTTTAGGGA TGGAGAATGT AGCAAATCAG AAGTCCCCAT ATTTCCCCAA CCAATACAGC 
CGAGACAAGG CTCTGCTGAG GCTTCCTTAT GGTCCTGGGA AATCTAGAGC CAACCAGATT 
CCCAAAGTAG CCTGGATCCC AGACGTTGAA AGCAGACAAG CCCCCTATGA CAATCTGAAT 
GATAAGGACC AAGAATTGGG AGAGTACTTA GCCAGGATGC TAGTTAAGTA CCCTGAGCTC 
ATGAATACCA ACCAGCTGAA GAGAGTGCCC AGCCCAGGCT CCTCAGAAGA TGACCTCCAA 
GAAGAAGAGC AGCTCGAGCA GGCCATCAAG GAGCATCTGG GTCAAGGAAG CTCCCAGGAA 
ATGGAGAAAC TGGCCAAGGT GAGCAAAAGG ATCCCTGCAG GATCCCTGAA GAATGAGGAT 
ACCCCAAATA GACAGTACCT GGATGAAGAT ATGCTCCTGA AAGTGCTAGA GTATCTCAAT 
CAAGAACAGG CAGAGCAGGG AAGGGAACAT CTTGCCAAAC GGGCCATGGA AAACATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245210.1
CDS	213..1952
Translation	MAESKAYRFGAVLLLIHLIFLVPGTEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIEKLRQQAHREESSPDYNPYQGISVPLQLKENGEESHLAESSRDVLSEDEWMRIILEALRQAENEPPSALKENKPYALNLEKNFPVDTPDDYETQQWPERKLKHMRFPLMYEENSRENPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPSNQKRERVDEEQKLYTDDEDDVYKTNNIAYEDVVGGEDWSPMEEKIETQTQEEVRDSKENTEKNEQINEEMKRSGHLGLPDEGNRKESKDQLSEDASKVITYLRRNLQIPPEDLIEMLKAGEKPNGLVEPEQDLELAVDLDDIPEADIDRPDMFQSKTLSKGGYPKAPGRGMMEALPDGLSVEDILNVLGMENVANQKSPYFPNQYSRDKALLRLPYGPGKSRANQIPKVAWIPDVESRQAPYDNLNDKDQELGEYLARMLVKYPELMNTNQLKRVPSPGSSEDDLQEEEQLEQAIKEHLGQGSSQEMEKLAKVSKRIPAGSLKNEDTPNRQYLDEDMLLKVLEYLNQEQAEQGREHLAKRAMENM

Target ORF information:

RefSeq Version	XM_006245148.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus secretogranin II (Scg2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245148.3

ORF Insert Sequence:

ATGGCTGAAT CGAAGGCTTA CCGATTTGGA GCAGTTCTGC TTCTTATCCA CTTAATTTTC 
CTTGTCCCTG GAACCGAAGC AGCTTCCTTC CAGCGAAACC AGCTGCTTCA GAAAGAACCA 
GACCTCAGAT TGGAGAATGT CCAGAAGTTT CCTAGTCCAG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCAGGCA GCAGGCCCAC AGAGAAGAAA GCAGCCCAGA CTACAATCCC 
TACCAAGGCA TCTCTGTTCC CCTTCAACTC AAAGAAAACG GAGAAGAAAG TCACTTGGCA 
GAGAGCTCAA GGGATGTCTT GAGTGAAGAC GAGTGGATGC GGATAATACT TGAGGCTTTG 
AGGCAGGCTG AAAATGAGCC GCCATCTGCC CTCAAGGAGA ACAAGCCCTA TGCCTTGAAT 
CTGGAGAAGA ACTTCCCTGT GGACACGCCT GATGACTATG AGACTCAACA ATGGCCTGAG 
AGGAAACTCA AGCACATGCG GTTCCCTCTC ATGTATGAAG AGAATTCCAG GGAAAACCCC 
TTCAAACGCA CAAACGAAAT AGTAGAAGAA CAGTACACAC CCCAAAGTCT TGCTACCCTG 
GAGTCTGTGT TCCAAGAGCT TGGGAAACTG ACAGGGCCAA GCAACCAGAA GCGTGAGAGG 
GTTGACGAGG AACAGAAGCT CTACACGGAC GATGAAGATG ACGTGTACAA GACCAACAAC 
ATTGCCTATG AAGATGTGGT CGGGGGAGAA GACTGGAGTC CTATGGAGGA GAAAATAGAG 
ACTCAAACCC AGGAAGAGGT GAGAGACAGC AAAGAGAACA CAGAAAAAAA CGAACAAATC 
AATGAAGAGA TGAAACGGTC AGGGCACTTG GGGCTCCCAG ATGAAGGTAA CCGGAAAGAG 
AGCAAAGACC AGCTCTCAGA GGACGCCTCC AAGGTCATCA CCTACTTGAG AAGGAATTTG 
CAGATACCCC CTGAAGACTT AATTGAGATG CTCAAAGCTG GGGAGAAACC AAATGGGTTG 
GTGGAGCCCG AGCAGGATCT GGAGCTTGCT GTTGACCTAG ATGACATCCC GGAAGCTGAC 
ATAGACCGCC CAGACATGTT TCAAAGTAAG ACGCTCTCCA AGGGTGGGTA TCCCAAGGCA 
CCTGGTCGAG GTATGATGGA GGCCTTGCCA GATGGCCTCA GTGTTGAAGA CATTTTAAAT 
GTTTTAGGGA TGGAGAATGT AGCAAATCAG AAGTCCCCAT ATTTCCCCAA CCAATACAGC 
CGAGACAAGG CTCTGCTGAG GCTTCCTTAT GGTCCTGGGA AATCTAGAGC CAACCAGATT 
CCCAAAGTAG CCTGGATCCC AGACGTTGAA AGCAGACAAG CCCCCTATGA CAATCTGAAT 
GATAAGGACC AAGAATTGGG AGAGTACTTA GCCAGGATGC TAGTTAAGTA CCCTGAGCTC 
ATGAATACCA ACCAGCTGAA GAGAGTGCCC AGCCCAGGCT CCTCAGAAGA TGACCTCCAA 
GAAGAAGAGC AGCTCGAGCA GGCCATCAAG GAGCATCTGG GTCAAGGAAG CTCCCAGGAA 
ATGGAGAAAC TGGCCAAGGT GAGCAAAAGG ATCCCTGCAG GATCCCTGAA GAATGAGGAT 
ACCCCAAATA GACAGTACCT GGATGAAGAT ATGCTCCTGA AAGTGCTAGA GTATCTCAAT 
CAAGAACAGG CAGAGCAGGG AAGGGAACAT CTTGCCAAAC GGGCCATGGA AAACATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scg2 ( XM_008767195.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765417.1 Rattus norvegicus secretogranin II (Scg2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa42952
Clone ID Related Accession (Same CDS sequence)	XM_008767195.2
Accession Version	XM_008767195.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	secretogranin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767195.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGAAT CGAAGGCTTA CCGATTTGGA GCAGTTCTGC TTCTTATCCA CTTAATTTTC 
CTTGTCCCTG GAACCGAAGC AGCTTCCTTC CAGCGAAACC AGCTGCTTCA GAAAGAACCA 
GACCTCAGAT TGGAGAATGT CCAGAAGTTT CCTAGTCCAG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCAGGCA GCAGGCCCAC AGAGAAGAAA GCAGCCCAGA CTACAATCCC 
TACCAAGGCA TCTCTGTTCC CCTTCAACTC AAAGAAAACG GAGAAGAAAG TCACTTGGCA 
GAGAGCTCAA GGGATGTCTT GAGTGAAGAC GAGTGGATGC GGATAATACT TGAGGCTTTG 
AGGCAGGCTG AAAATGAGCC GCCATCTGCC CTCAAGGAGA ACAAGCCCTA TGCCTTGAAT 
CTGGAGAAGA ACTTCCCTGT GGACACGCCT GATGACTATG AGACTCAACA ATGGCCTGAG 
AGGAAACTCA AGCACATGCG GTTCCCTCTC ATGTATGAAG AGAATTCCAG GGAAAACCCC 
TTCAAACGCA CAAACGAAAT AGTAGAAGAA CAGTACACAC CCCAAAGTCT TGCTACCCTG 
GAGTCTGTGT TCCAAGAGCT TGGGAAACTG ACAGGGCCAA GCAACCAGAA GCGTGAGAGG 
GTTGACGAGG AACAGAAGCT CTACACGGAC GATGAAGATG ACGTGTACAA GACCAACAAC 
ATTGCCTATG AAGATGTGGT CGGGGGAGAA GACTGGAGTC CTATGGAGGA GAAAATAGAG 
ACTCAAACCC AGGAAGAGGT GAGAGACAGC AAAGAGAACA CAGAAAAAAA CGAACAAATC 
AATGAAGAGA TGAAACGGTC AGGGCACTTG GGGCTCCCAG ATGAAGGTAA CCGGAAAGAG 
AGCAAAGACC AGCTCTCAGA GGACGCCTCC AAGGTCATCA CCTACTTGAG AAGGTTAGTG 
AATGCTGTGG GCAGTGGGAG GTCCCAGAGT GGGCAAAACG GGGACAGGGC AGCCAGGCTT 
CTTGAGAGGC CCCTTGATTC TCAGTCTATT TATCAGCTGA TTGAAATCTC CAGGAATTTG 
CAGATACCCC CTGAAGACTT AATTGAGATG CTCAAAGCTG GGGAGAAACC AAATGGGTTG 
GTGGAGCCCG AGCAGGATCT GGAGCTTGCT GTTGACCTAG ATGACATCCC GGAAGCTGAC 
ATAGACCGCC CAGACATGTT TCAAAGTAAG ACGCTCTCCA AGGGTGGGTA TCCCAAGGCA 
CCTGGTCGAG GTATGATGGA GGCCTTGCCA GATGGCCTCA GTGTTGAAGA CATTTTAAAT 
GTTTTAGGGA TGGAGAATGT AGCAAATCAG AAGTCCCCAT ATTTCCCCAA CCAATACAGC 
CGAGACAAGG CTCTGCTGAG GCTTCCTTAT GGTCCTGGGA AATCTAGAGC CAACCAGATT 
CCCAAAGTAG CCTGGATCCC AGACGTTGAA AGCAGACAAG CCCCCTATGA CAATCTGAAT 
GATAAGGACC AAGAATTGGG AGAGTACTTA GCCAGGATGC TAGTTAAGTA CCCTGAGCTC 
ATGAATACCA ACCAGCTGAA GAGAGTGCCC AGCCCAGGCT CCTCAGAAGA TGACCTCCAA 
GAAGAAGAGC AGCTCGAGCA GGCCATCAAG GAGCATCTGG GTCAAGGAAG CTCCCAGGAA 
ATGGAGAAAC TGGCCAAGGT GAGCAAAAGG ATCCCTGCAG GATCCCTGAA GAATGAGGAT 
ACCCCAAATA GACAGTACCT GGATGAAGAT ATGCTCCTGA AAGTGCTAGA GTATCTCAAT 
CAAGAACAGG CAGAGCAGGG AAGGGAACAT CTTGCCAAAC GGGCCATGGA AAACATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765417.1
CDS	334..2193
Translation	MAESKAYRFGAVLLLIHLIFLVPGTEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIEKLRQQAHREESSPDYNPYQGISVPLQLKENGEESHLAESSRDVLSEDEWMRIILEALRQAENEPPSALKENKPYALNLEKNFPVDTPDDYETQQWPERKLKHMRFPLMYEENSRENPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPSNQKRERVDEEQKLYTDDEDDVYKTNNIAYEDVVGGEDWSPMEEKIETQTQEEVRDSKENTEKNEQINEEMKRSGHLGLPDEGNRKESKDQLSEDASKVITYLRRLVNAVGSGRSQSGQNGDRAARLLERPLDSQSIYQLIEISRNLQIPPEDLIEMLKAGEKPNGLVEPEQDLELAVDLDDIPEADIDRPDMFQSKTLSKGGYPKAPGRGMMEALPDGLSVEDILNVLGMENVANQKSPYFPNQYSRDKALLRLPYGPGKSRANQIPKVAWIPDVESRQAPYDNLNDKDQELGEYLARMLVKYPELMNTNQLKRVPSPGSSEDDLQEEEQLEQAIKEHLGQGSSQEMEKLAKVSKRIPAGSLKNEDTPNRQYLDEDMLLKVLEYLNQEQAEQGREHLAKRAMENM

Target ORF information:

RefSeq Version	XM_008767195.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus secretogranin II (Scg2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767195.2

ORF Insert Sequence:

ATGGCTGAAT CGAAGGCTTA CCGATTTGGA GCAGTTCTGC TTCTTATCCA CTTAATTTTC 
CTTGTCCCTG GAACCGAAGC AGCTTCCTTC CAGCGAAACC AGCTGCTTCA GAAAGAACCA 
GACCTCAGAT TGGAGAATGT CCAGAAGTTT CCTAGTCCAG AAATGATCAG GGCTTTGGAG 
TACATAGAAA AGCTCAGGCA GCAGGCCCAC AGAGAAGAAA GCAGCCCAGA CTACAATCCC 
TACCAAGGCA TCTCTGTTCC CCTTCAACTC AAAGAAAACG GAGAAGAAAG TCACTTGGCA 
GAGAGCTCAA GGGATGTCTT GAGTGAAGAC GAGTGGATGC GGATAATACT TGAGGCTTTG 
AGGCAGGCTG AAAATGAGCC GCCATCTGCC CTCAAGGAGA ACAAGCCCTA TGCCTTGAAT 
CTGGAGAAGA ACTTCCCTGT GGACACGCCT GATGACTATG AGACTCAACA ATGGCCTGAG 
AGGAAACTCA AGCACATGCG GTTCCCTCTC ATGTATGAAG AGAATTCCAG GGAAAACCCC 
TTCAAACGCA CAAACGAAAT AGTAGAAGAA CAGTACACAC CCCAAAGTCT TGCTACCCTG 
GAGTCTGTGT TCCAAGAGCT TGGGAAACTG ACAGGGCCAA GCAACCAGAA GCGTGAGAGG 
GTTGACGAGG AACAGAAGCT CTACACGGAC GATGAAGATG ACGTGTACAA GACCAACAAC 
ATTGCCTATG AAGATGTGGT CGGGGGAGAA GACTGGAGTC CTATGGAGGA GAAAATAGAG 
ACTCAAACCC AGGAAGAGGT GAGAGACAGC AAAGAGAACA CAGAAAAAAA CGAACAAATC 
AATGAAGAGA TGAAACGGTC AGGGCACTTG GGGCTCCCAG ATGAAGGTAA CCGGAAAGAG 
AGCAAAGACC AGCTCTCAGA GGACGCCTCC AAGGTCATCA CCTACTTGAG AAGGTTAGTG 
AATGCTGTGG GCAGTGGGAG GTCCCAGAGT GGGCAAAACG GGGACAGGGC AGCCAGGCTT 
CTTGAGAGGC CCCTTGATTC TCAGTCTATT TATCAGCTGA TTGAAATCTC CAGGAATTTG 
CAGATACCCC CTGAAGACTT AATTGAGATG CTCAAAGCTG GGGAGAAACC AAATGGGTTG 
GTGGAGCCCG AGCAGGATCT GGAGCTTGCT GTTGACCTAG ATGACATCCC GGAAGCTGAC 
ATAGACCGCC CAGACATGTT TCAAAGTAAG ACGCTCTCCA AGGGTGGGTA TCCCAAGGCA 
CCTGGTCGAG GTATGATGGA GGCCTTGCCA GATGGCCTCA GTGTTGAAGA CATTTTAAAT 
GTTTTAGGGA TGGAGAATGT AGCAAATCAG AAGTCCCCAT ATTTCCCCAA CCAATACAGC 
CGAGACAAGG CTCTGCTGAG GCTTCCTTAT GGTCCTGGGA AATCTAGAGC CAACCAGATT 
CCCAAAGTAG CCTGGATCCC AGACGTTGAA AGCAGACAAG CCCCCTATGA CAATCTGAAT 
GATAAGGACC AAGAATTGGG AGAGTACTTA GCCAGGATGC TAGTTAAGTA CCCTGAGCTC 
ATGAATACCA ACCAGCTGAA GAGAGTGCCC AGCCCAGGCT CCTCAGAAGA TGACCTCCAA 
GAAGAAGAGC AGCTCGAGCA GGCCATCAAG GAGCATCTGG GTCAAGGAAG CTCCCAGGAA 
ATGGAGAAAC TGGCCAAGGT GAGCAAAAGG ATCCCTGCAG GATCCCTGAA GAATGAGGAT 
ACCCCAAATA GACAGTACCT GGATGAAGAT ATGCTCCTGA AAGTGCTAGA GTATCTCAAT 
CAAGAACAGG CAGAGCAGGG AAGGGAACAT CTTGCCAAAC GGGCCATGGA AAACATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of food deprivation on the hypothalamic gene expression of the secretogranin II-derived peptide EM66 in rat.
Neuroreport28(16)1049-1053(2017 Nov)
Trebak F,Dubuc I,Picot M,Alaoui A,Leprince J,Pr?vost G,Anouar Y,Magoul R,Chartrel N

Localization of manserin, a secretogranin II-derived neuropeptide, in the oviduct of female rats.
Acta histochemica116(3)522-6(2014 Apr)
Ida-Eto M,Nomura M,Ohkawara T,Narita N,Narita M

Subtype-specific parafollicular localization of the neuropeptide manserin in the rat thyroid gland.
Acta histochemica115(2)190-4(2013 Mar)
Ohkawara T,Oyabu A,Ida-Eto M,Tashiro Y,Narita N,Narita M

Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.
PloS one7(5)e37401(2012)
R?sj? H,Stridsberg M,Florholmen G,Stensl?kken KO,Ottesen AH,Sjaastad I,Husberg C,Dahl MB,?ie E,Louch WE,Omland T,Christensen G

Corticotropin-releasing factor binding protein enters the regulated secretory pathway in neuroendocrine cells and cortical neurons.
Neuropeptides45(4)273-9(2011 Aug)
Blanco EH,Z??iga JP,Andr?s ME,Alvarez AR,Gysling K

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Scg2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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