Gene Symbol | DML1 |
Entrez Gene ID | 818224 |
Full Name | demeter-like 1 |
Synonyms | AtROS1,F1O11.12,F1O11_12,REPRESSOR OF SILENCING1,ROS1,demeter-like 1 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
ORF » Species Summary » Arabidopsis thaliana » DML1 cDNA ORF clone
Gene Symbol | DML1 |
Entrez Gene ID | 818224 |
Full Name | demeter-like 1 |
Synonyms | AtROS1,F1O11.12,F1O11_12,REPRESSOR OF SILENCING1,ROS1,demeter-like 1 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
mRNA | Protein | Name |
---|---|---|
NM_129207.5 | NP_181190.3 | demeter-like 1 |
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.
Lin X, Kaul S, Rounsley S, Shea TP, Benito MI, Town CD, Fujii CY, Mason T, Bowman CL, Barnstead M, Feldblyum TV, Buell CR, Ketchum KA, Lee J, Ronning CM, Koo HL, Moffat KS, Cronin LA, Shen M, Pai G, Van Aken S, Umayam L, Tallon LJ, Gill JE, Adams MD, Carrera AJ, Creasy TH, Goodman HM, Somerville CR, Copenhaver GP, Preuss D, Nierman WC, White O, Eisen JA, Salzberg SL, Fraser CM, Venter JC
Nature402(6763)761-8(1999 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our results suggest that ROS1-mediated active DNA demethylation requires MET18-dependent transfer of the iron-sulfur cluster, highlighting an important role of the CIA pathway in epigenetic regulation.
Title: MET18 Connects the Cytosolic Iron-Sulfur Cluster Assembly Pathway to Active DNA Demethylation in Arabidopsis.
Transgenic tobacco overexpressing AtROS1 showed tolerance to salt stress that could have been due to the higher expression levels of the genes encoding enzymes of the flavonoid biosynthetic and antioxidant pathways.
Title: AtROS1 overexpression provides evidence for epigenetic regulation of genes encoding enzymes of flavonoid biosynthesis and antioxidant pathways during salt stress in transgenic tobacco.
We propose that the ROS1 locus functions as an epigenetic rheostat, tuning the level of demethylase activity in response to methylation alterations, thus ensuring epigenomic stability.
Title: Methylation-sensitive expression of a DNA demethylase gene serves as an epigenetic rheostat.
ROS1, DML2, and DML3 play a role in fungal disease resistance in Arabidopsis
Title: DNA demethylases target promoter transposable elements to positively regulate stress responsive genes in Arabidopsis.
ROS1 mediated DNA demethylation combats the activity of RNA-directed DNA methylation to influence the initiation of stomatal lineage cells.
Title: Overproduction of stomatal lineage cells in Arabidopsis mutants defective in active DNA demethylation.
The following DML1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DML1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OAb08933 | |
Clone ID Related Accession (Same CDS sequence) | NM_129207.5 | |
Accession Version | NM_129207.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4182bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-13 | |
Organism | Arabidopsis thaliana(thale cress) | |
Product | demeter-like 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003071). On Sep 12, 2016 this sequence version replaced NM_129207.4. |
1 | ATGGAGAAAC AGAGGAGAGA AGAAAGCAGC TTTCAACAAC CTCCATGGAT TCCTCAGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_181190.3 |
CDS | 294..4475 |
Translation |
Target ORF information:
Target ORF information:
|
NM_129207.5 |
1 | ATGGAGAAAC AGAGGAGAGA AGAAAGCAGC TTTCAACAAC CTCCATGGAT TCCTCAGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. |