SERPINA14 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	SERPINA14
Entrez Gene ID	286871
Full Name	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14
Synonyms	UTMP
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174797.3	NP_777222.1	uterine milk protein precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SERPINA14	XP_005623983.1
Bos taurus (cattle)	SERPINA14	NP_777222.1

Gene Ontology
Bibliography

Related articles in PubMed

Crosstalk between uterine serpin (SERPINA14) and pregnancy-associated glycoproteins at the fetal-maternal interface in pregnant dairy heifers experimentally infected with Neospora caninum.
Serrano-P?rez B, Hansen PJ, Mur-Novales R, Garc?a-Ispierto I, de Sousa NM, Beckers JF, Almer?a S, L?pez-Gatius F
Theriogenology86(3)824-30(2016 Aug)

Evidence for estrogen-dependent uterine serpin (SERPINA14) expression during estrus in the bovine endometrial glandular epithelium and lumen.
Ulbrich SE, Frohlich T, Schulke K, Englberger E, Waldschmitt N, Arnold GJ, Reichenbach HD, Reichenbach M, Wolf E, Meyer HH, Bauersachs S
Biology of reproduction81(4)795-805(2009 Oct)

Pattern of expression of the uterine milk protein gene and its association with productive life in dairy cattle.
Khatib H, Schutzkus V, Chang YM, Rosa GJ
Journal of dairy science90(5)2427-33(2007 May)

Pepsin-inhibitory activity of the uterine serpins.
Mathialagan N, Hansen TR
Proceedings of the National Academy of Sciences of the United States of America93(24)13653-8(1996 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study examines expression patterns of the genes SERPINA14, PAG, and PAG2 at the fetal-maternal interface in dairy heifers experimentally infected with N caninum during the second trimester of pregnancy, when most abortions takes place in natural conditions.
Title: Crosstalk between uterine serpin (SERPINA14) and pregnancy-associated glycoproteins at the fetal-maternal interface in pregnant dairy heifers experimentally infected with Neospora caninum.

SERPINA14 appears distinctly in endometrium during the estrus phase.
Title: Evidence for estrogen-dependent uterine serpin (SERPINA14) expression during estrus in the bovine endometrial glandular epithelium and lumen.

Differential allelic expression of uterine milk protein gene was observed in reproductive tissues obtained from 9 heterozygous individuals
Title: Pattern of expression of the uterine milk protein gene and its association with productive life in dairy cattle.

The following SERPINA14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SERPINA14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa44787	NM_174797.3 Latest version!	Bos taurus serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14 (SERPINA14), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$258.30 $369.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SERPINA14 ( NM_174797.3 ) cDNA ORF clone, Bos taurus(cattle) -> NP_777222.1 Bos taurus serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14 (SERPINA14), mRNA.

Price & Availability↑

CloneID	OBa44787
Clone ID Related Accession (Same CDS sequence)	NM_174797.3
Accession Version	NM_174797.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Bos taurus(cattle)
Product	uterine milk protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L22095.1. On Aug 30, 2012 this sequence version replaced NM_174797.2. ##Evidence-Data-START## Transcript exon combination :: L22095.1, BC149763.1 [ECO:0000332] ##Evidence-Data-END##

ATGTCCCACG GGAGAATGAA TCTGGCCCTG TCTCTGGTCT TCATCCTCTG TGGCCTGTTT 
AATAGCATCT TCTGTGAAAA GCAACAACAC TCTCAAAAGC ACATGAACCT AGTCTTATTA 
AAGAAAATTT CAGCTCTCTC CCAGAAGATG GAAGCTCACC CTAAGGATTT TGCCCAAGAA 
TTGTTCAAGG CTTTGATAAT TGAGGATCCC AGAAAGAATA TCATCTTCTC CCCCATGGCC 
ATGACCACCA CCCTGGCCAC CCTCTCCCTG GGGATCAAGT CTACAATGAG AACCCACCAC 
CCTGAGGACC TGAAACTTGA GCCCAAACTG TTGGATGTGC ACAAGTACTT ACAGCCTCTG 
GTCCACGTGG GGCGTGAGCT AGTGAAGCAG AAGGTACTGA AGCACCAGCA CATTCTCTTT 
ATCAACAGAA AAATGATGGT CAACCAGATG CTTCTACAGC AGATAAGCAA GCTGCAGGGA 
ATGGACATCC AGATGATTGA CTTTACAGAT ATAGAAAAAG CCAAGAAGAC CATCAGCCAC 
CATGTGGCTG AAAAAACACA TACGAAAATC ACAAACTTAA TCACCGACCT GAACCCTGAG 
ACCATCCTGT GTCTTGTTAA CCACATTTTC TTCAAAGGCA TCTTGAAAAG AGCTTTTCAG 
CCCAAACTCA CCCAGAAGGA GGTCTTCTTT GTGAATGACC AAACCAAAGT GCAGGTGGAC 
ATGATGAGAA AGACAGAACG GATGCTTTAC AGCCGGTCAG AGGAGCTACA TGCTACGATG 
GTTAAGATGC CTTGCAAAGG AAATGTGTCC CTAACTCTCA TGCTTCCAGA TGCCGGACAA 
TTTGACACTG ATCTTAAAAA GATGACTGCT AAGCGAGCTA AACTTCAGAA AATCAGTGAC 
TTCAGACTGG TGCGCTTAAT TTTGCCCAAG TTGAAGATCT CCTTCAAGAT AAACTTTAAG 
CATCTGCTTC CCAAGATTGA CCCCAAACAT ATACTGACTG CCACAGCAAT CTCACAGGCC 
ATCACATCGA AGGCTCCCCT GCCTAATTTG GAGGCCCTAC ATCAAGCTGA GATAGAGCTG 
AGCGAGCACG CCTTAACCGT GGACACAGCC ATTCACACAG ATAATCTGTT GAAAGTCCCA 
GTGAAGGCAA AGGAGGTCCC GGCGGTCGTG AAAGTCCCAA TGAAGGCAAA GGAGGTCCCG 
GCGGTCGTGA AAGTCCCAAT GAACACAAAG GAGGTCCCAG TGGTCGTGAA AGTCCCAATG 
AACACAAAGG AGGTCCCAGT GGTCGTGAAG GTCAACAGAC CCTTCTTGCT GTTTGTGGAG 
GATGAGAAGA CTCAAAGAGA CCTCTTTGTG GGCAAAGTCC TCAACCCCCA AGTTGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777222.1
CDS	17..1396
Translation	MSHGRMNLALSLVFILCGLFNSIFCEKQQHSQKHMNLVLLKKISALSQKMEAHPKDFAQELFKALIIEDPRKNIIFSPMAMTTTLATLSLGIKSTMRTHHPEDLKLEPKLLDVHKYLQPLVHVGRELVKQKVLKHQHILFINRKMMVNQMLLQQISKLQGMDIQMIDFTDIEKAKKTISHHVAEKTHTKITNLITDLNPETILCLVNHIFFKGILKRAFQPKLTQKEVFFVNDQTKVQVDMMRKTERMLYSRSEELHATMVKMPCKGNVSLTLMLPDAGQFDTDLKKMTAKRAKLQKISDFRLVRLILPKLKISFKINFKHLLPKIDPKHILTATAISQAITSKAPLPNLEALHQAEIELSEHALTVDTAIHTDNLLKVPVKAKEVPAVVKVPMKAKEVPAVVKVPMNTKEVPVVVKVPMNTKEVPVVVKVNRPFLLFVEDEKTQRDLFVGKVLNPQVE

Target ORF information:

RefSeq Version	NM_174797.3
Organism	Bos taurus(cattle)
Definition	Bos taurus serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14 (SERPINA14), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174797.3

ORF Insert Sequence:

ATGTCCCACG GGAGAATGAA TCTGGCCCTG TCTCTGGTCT TCATCCTCTG TGGCCTGTTT 
AATAGCATCT TCTGTGAAAA GCAACAACAC TCTCAAAAGC ACATGAACCT AGTCTTATTA 
AAGAAAATTT CAGCTCTCTC CCAGAAGATG GAAGCTCACC CTAAGGATTT TGCCCAAGAA 
TTGTTCAAGG CTTTGATAAT TGAGGATCCC AGAAAGAATA TCATCTTCTC CCCCATGGCC 
ATGACCACCA CCCTGGCCAC CCTCTCCCTG GGGATCAAGT CTACAATGAG AACCCACCAC 
CCTGAGGACC TGAAACTTGA GCCCAAACTG TTGGATGTGC ACAAGTACTT ACAGCCTCTG 
GTCCACGTGG GGCGTGAGCT AGTGAAGCAG AAGGTACTGA AGCACCAGCA CATTCTCTTT 
ATCAACAGAA AAATGATGGT CAACCAGATG CTTCTACAGC AGATAAGCAA GCTGCAGGGA 
ATGGACATCC AGATGATTGA CTTTACAGAT ATAGAAAAAG CCAAGAAGAC CATCAGCCAC 
CATGTGGCTG AAAAAACACA TACGAAAATC ACAAACTTAA TCACCGACCT GAACCCTGAG 
ACCATCCTGT GTCTTGTTAA CCACATTTTC TTCAAAGGCA TCTTGAAAAG AGCTTTTCAG 
CCCAAACTCA CCCAGAAGGA GGTCTTCTTT GTGAATGACC AAACCAAAGT GCAGGTGGAC 
ATGATGAGAA AGACAGAACG GATGCTTTAC AGCCGGTCAG AGGAGCTACA TGCTACGATG 
GTTAAGATGC CTTGCAAAGG AAATGTGTCC CTAACTCTCA TGCTTCCAGA TGCCGGACAA 
TTTGACACTG ATCTTAAAAA GATGACTGCT AAGCGAGCTA AACTTCAGAA AATCAGTGAC 
TTCAGACTGG TGCGCTTAAT TTTGCCCAAG TTGAAGATCT CCTTCAAGAT AAACTTTAAG 
CATCTGCTTC CCAAGATTGA CCCCAAACAT ATACTGACTG CCACAGCAAT CTCACAGGCC 
ATCACATCGA AGGCTCCCCT GCCTAATTTG GAGGCCCTAC ATCAAGCTGA GATAGAGCTG 
AGCGAGCACG CCTTAACCGT GGACACAGCC ATTCACACAG ATAATCTGTT GAAAGTCCCA 
GTGAAGGCAA AGGAGGTCCC GGCGGTCGTG AAAGTCCCAA TGAAGGCAAA GGAGGTCCCG 
GCGGTCGTGA AAGTCCCAAT GAACACAAAG GAGGTCCCAG TGGTCGTGAA AGTCCCAATG 
AACACAAAGG AGGTCCCAGT GGTCGTGAAG GTCAACAGAC CCTTCTTGCT GTTTGTGGAG 
GATGAGAAGA CTCAAAGAGA CCTCTTTGTG GGCAAAGTCC TCAACCCCCA AGTTGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Crosstalk between uterine serpin (SERPINA14) and pregnancy-associated glycoproteins at the fetal-maternal interface in pregnant dairy heifers experimentally infected with Neospora caninum.
Theriogenology86(3)824-30(2016 Aug)
Serrano-P?rez B,Hansen PJ,Mur-Novales R,Garc?a-Ispierto I,de Sousa NM,Beckers JF,Almer?a S,L?pez-Gatius F

Evidence for estrogen-dependent uterine serpin (SERPINA14) expression during estrus in the bovine endometrial glandular epithelium and lumen.
Biology of reproduction81(4)795-805(2009 Oct)
Ulbrich SE,Frohlich T,Schulke K,Englberger E,Waldschmitt N,Arnold GJ,Reichenbach HD,Reichenbach M,Wolf E,Meyer HH,Bauersachs S

Pattern of expression of the uterine milk protein gene and its association with productive life in dairy cattle.
Journal of dairy science90(5)2427-33(2007 May)
Khatib H,Schutzkus V,Chang YM,Rosa GJ

Pepsin-inhibitory activity of the uterine serpins.
Proceedings of the National Academy of Sciences of the United States of America93(24)13653-8(1996 Nov)
Mathialagan N,Hansen TR

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SERPINA14 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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