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  • Entrez Gene ID (e.g. 7157)
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  • gene name (e.g. tumor protein p53)
  • gene synonyms (e.g. FLJ92943)
  • Ensembl ID (e.g. ENSG0000141510)
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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Highly sodium permeable acetylcholine nicotinic receptors Trafficking of AMPA receptors
Activation of NMDA receptor upon glutamate binding and postsynaptic events Unblocking of NMDA receptor, glutamate binding and activation
Post NMDA receptor activation events RSK activation
Activation of Ca-permeable Kainate Receptor Presynaptic function of Kainate receptors
Inwardly rectifying K+ channels Classical Kir channels
Tandem pore domain halothane-inhibited K+ channel (THIK) Mitochondrial translation
Mitochondrial translation termination Anchoring of the basal body to the plasma membrane
Disease Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
Inhibition of Signaling by Overexpressed EGFR Signaling by FGFR1 in disease
Activated point mutants of FGFR2 FGFR4 mutant receptor activation
Signaling by NOTCH1 in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Loss of Function of SMAD2/3 in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer S37 mutants of beta-catenin aren't phosphorylated
TCF7L2 mutants don't bind CTBP Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
Retinoid cycle disease events ABC transporter disorders
Diseases of metabolism Diseases of carbohydrate metabolism
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA
Defects in biotin (Btn) metabolism Defective HLCS causes multiple carboxylase deficiency
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Defective CHSY1 causes TPBS
Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Reverse Transcription of HIV RNA Transcription of the HIV genome
RNA Polymerase II HIV Promoter Escape Tat-mediated elongation of the HIV-1 transcript
Assembly Of The HIV Virion Nuclear import of Rev protein
Interactions of Tat with host cellular proteins Nef mediated downregulation of CD28 cell surface expression
Influenza Infection Viral mRNA Translation
Host Interactions with Influenza Factors Response of Mtb to phagocytosis
Diseases associated with the TLR signaling cascade MyD88 deficiency (TLR2/4)
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) IkBA variant leads to EDA-ID
Adaptive Immune System Downstream TCR signaling
Activation of NF-kappaB in B cells Activation of RAS in B cells
AKT phosphorylates targets in the cytosol Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Rap1 signalling MyD88 cascade initiated on plasma membrane
IRAK1 recruits IKK complex VEGF ligand-receptor interactions
VEGFA-VEGFR2 Pathway Neurophilin interactions with VEGF and VEGFR
Signaling by ERBB4 MAPK1 (ERK2) activation
RHO GTPases activate PAKs RHO GTPases activate IQGAPs
TGF-beta receptor signaling activates SMADs TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Downregulation of SMAD2/3:SMAD4 transcriptional activity
Pre-NOTCH Transcription and Translation NOTCH2 intracellular domain regulates transcription
Signaling by GPCR P2Y receptors
Adenosine P1 receptors Class C/3 (Metabotropic glutamate/pheromone receptors)
G beta:gamma signalling through PI3Kgamma Opioid Signalling
PLC beta mediated events Beta-catenin phosphorylation cascade
Repression of WNT target genes Binding of TCF/LEF:CTNNB1 to target gene promoters
Negative regulation of TCF-dependent signaling by DVL-interacting proteins Beta-catenin independent WNT signaling
PCP/CE pathway WNT5A-dependent internalization of FZD4
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) IGF1R signaling cascade
SHC-related events triggered by IGF1R Hedgehog 'off' state
Hedgehog 'on' state Notch-HLH transcription pathway
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