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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Post-chaperonin tubulin folding pathway Gamma carboxylation, hypusine formation and arylsulfatase activation
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins Removal of aminoterminal propeptides from gamma-carboxylated proteins
Synthesis of substrates in N-glycan biosythesis Synthesis of GDP-mannose
ER Quality Control Compartment (ERQC) COPII (Coat Protein 2) Mediated Vesicle Transport
Reactions specific to the complex N-glycan synthesis pathway N-Glycan antennae elongation
O-linked glycosylation of mucins SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO E3 ligases SUMOylate target proteins
Metabolism of Angiotensinogen to Angiotensins Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) ATF6 (ATF6-alpha) activates chaperones
IRE1alpha activates chaperones Neuronal System
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Reuptake of GABA
Degradation of GABA Enzymatic degradation of dopamine by COMT
Acetylcholine Binding And Downstream Events Activation of Kainate Receptors upon glutamate binding
GABA B receptor activation Activation of GABAB receptors
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) TWIK related potassium channel (TREK)
Cilium Assembly Signaling by EGFRvIII in Cancer
Constitutive Signaling by EGFRvIII Signaling by activated point mutants of FGFR1
Signaling by FGFR2 amplification mutants Signaling by activated point mutants of FGFR3
PI3K/AKT Signaling in Cancer Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
Signaling by TGF-beta Receptor Complex in Cancer TGFBR2 Kinase Domain Mutants in Cancer
TGFBR1 LBD Mutants in Cancer AXIN mutants destabilize the destruction complex, activating WNT signaling
AXIN missense mutants destabilize the destruction complex phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
S45 mutants of beta-catenin aren't phosphorylated T41 mutants of beta-catenin aren't phosphorylated
Misspliced GSK3beta mutants stabilize beta-catenin Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
Diseases associated with visual transduction Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate Defective CHST6 causes MCDC1
Early Phase of HIV Life Cycle Uncoating of the HIV Virion
Plus-strand DNA synthesis Integration of provirus
Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat
Nef mediated downregulation of MHC class I complex cell surface expression vRNP Assembly
Viral Messenger RNA Synthesis Viral RNP Complexes in the Host Cell Nucleus
Influenza Virus Induced Apoptosis Toxicity of botulinum toxin type E (BoNT/E)
Toxicity of botulinum toxin type F (BoNT/F) Toxicity of botulinum toxin type G (BoNT/G)
TICAM1 deficiency - HSE TCR signaling
Phosphorylation of CD3 and TCR zeta chains CD28 dependent Vav1 pathway
MHC class II antigen presentation Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Activation of the AP-1 family of transcription factors TRAF6 mediated induction of TAK1 complex
Toll Like Receptor 9 (TLR9) Cascade Activation of C3 and C5
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Regulation of cholesterol biosynthesis by SREBP (SREBF)
Activation of gene expression by SREBF (SREBP) Metabolism of steroid hormones
Glucocorticoid biosynthesis Estrogen biosynthesis
Vitamin D (calciferol) metabolism Synthesis of PA
Synthesis of PS Acyl chain remodelling of PS
Acyl chain remodelling of PI Synthesis of PG
Synthesis of PIPs at the ER membrane Synthesis of PIPs at the plasma membrane
Synthesis of PIPs at the early endosome membrane Linoleic acid (LA) metabolism
Sphingolipid metabolism Sphingolipid de novo biosynthesis
Integration of energy metabolism Acetylcholine regulates insulin secretion
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion eNOS activation
Pyruvate metabolism and Citric Acid (TCA) cycle Pyrimidine catabolism
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