LTB cDNA ORF clone, Pan troglodytes(chimpanzee)

Gene
Clones
gRNAs

Summary

Gene Symbol	LTB
Entrez Gene ID	744486
Full Name	lymphotoxin beta
General protein information	Preferred Names lymphotoxin beta Names lymphotoxin-beta LT-beta TNF-C lymphotoxin beta (TNF superfamily, member 3) tumor necrosis factor C tumor necrosis factor ligand superfamily member 3
Gene Type	protein-coding
Organism	Pan troglodytes(chimpanzee)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001076784.1	NP_001070252.1	lymphotoxin-beta
XM_009450871.2	XP_009449146.2	lymphotoxin-beta isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	LTB	NP_002332.1
Pan troglodytes (chimpanzee)	LTB	NP_001070252.1
Canis lupus familiaris (dog)	LTB	NP_001028682.1
Mus musculus (house mouse)	Ltb	NP_032544.1
Rattus norvegicus (Norway rat)	Ltb	NP_997672.1
	LTB	NP_001040615.1
Bos taurus (cattle)	LTB	XP_002697417.1

Gene Ontology
Bibliography

Related articles in PubMed

Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
Shiina T, Ota M, Shimizu S, Katsuyama Y, Hashimoto N, Takasu M, Anzai T, Kulski JK, Kikkawa E, Naruse T, Kimura N, Yanagiya K, Watanabe A, Hosomichi K, Kohara S, Iwamoto C, Umehara Y, Meyer A, Wanner V, Sano K, Macquin C, Ikeo K, Tokunaga K, Gojobori T, Inoko H, Bahram S
Genetics173(3)1555-70(2006 Jul)

Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence.
Anzai T, Shiina T, Kimura N, Yanagiya K, Kohara S, Shigenari A, Yamagata T, Kulski JK, Naruse TK, Fujimori Y, Fukuzumi Y, Yamazaki M, Tashiro H, Iwamoto C, Umehara Y, Imanishi T, Meyer A, Ikeo K, Gojobori T, Bahram S, Inoko H
Proceedings of the National Academy of Sciences of the United States of America100(13)7708-13(2003 Jun)

Comparative genomic analysis of the MHC: the evolution of class I duplication blocks, diversity and complexity from shark to man.
Kulski JK, Shiina T, Anzai T, Kohara S, Inoko H
Immunological reviews19095-122(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LTB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LTB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OPc85960	XM_009450871.2 Latest version!	Pan troglodytes lymphotoxin beta (LTB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
OPc00193	NM_001076784.1 Latest version!	Pan troglodytes lymphotoxin beta (LTB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LTB ( XM_009450871.2 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_009449146.2 Pan troglodytes lymphotoxin beta (LTB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OPc85960
Clone ID Related Accession (Same CDS sequence)	XM_009450871.2
Accession Version	XM_009450871.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 270bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-19
Organism	Pan troglodytes(chimpanzee)
Product	lymphotoxin-beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036885.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 2, 2016 this sequence version replaced XM_009450871.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGCCC CCTGCTCTGG CTCTGGTTCA GTCTCAATGG GGGCACTGGG GCTGGAGGGC 
AGGGGTGGGA GGCTCCAGGG GAGGGGTTCC CTCCTGCTAG CTGTGGCAGG AGCCACTTCT 
CTGGTGACCT TGTTGCTGGC GGTGCCTATC ACTGTCCTGG CTGTGCTGGC CTTAGTGCCC 
CAGGATCAGG GAGGACTGGG TTTCAGAAGC TGCCAGAGGA GGAGCCAGAA ACAGATCTCA 
GCCCCGGGCT CCCAGCTGCC CACCTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009449146.2
CDS	871..1140
Translation	MKAPCSGSGSVSMGALGLEGRGGRLQGRGSLLLAVAGATSLVTLLLAVPITVLAVLALVPQDQGGLGFRSCQRRSQKQISAPGSQLPTS

Target ORF information:

RefSeq Version	XM_009450871.2
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes lymphotoxin beta (LTB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009450871.2

ORF Insert Sequence:

ATGAAAGCCC CCTGCTCTGG CTCTGGTTCA GTCTCAATGG GGGCACTGGG GCTGGAGGGC 
AGGGGTGGGA GGCTCCAGGG GAGGGGTTCC CTCCTGCTAG CTGTGGCAGG AGCCACTTCT 
CTGGTGACCT TGTTGCTGGC GGTGCCTATC ACTGTCCTGG CTGTGCTGGC CTTAGTGCCC 
CAGGATCAGG GAGGACTGGG TTTCAGAAGC TGCCAGAGGA GGAGCCAGAA ACAGATCTCA 
GCCCCGGGCT CCCAGCTGCC CACCTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LTB ( NM_001076784.1 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> NP_001070252.1 Pan troglodytes lymphotoxin beta (LTB), mRNA.

Price & Availability↑

CloneID	OPc00193
Clone ID Related Accession (Same CDS sequence)	NM_001076784.1
Accession Version	NM_001076784.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Pan troglodytes(chimpanzee)
Product	lymphotoxin-beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB210168.1. On Oct 9, 2006 this sequence version replaced XM_001153356.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02045700, SAMN02045701 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCAC TGGGGCTGGA GGGCAGGGGT GGGAGGCTCC AGGGGAGGGG TTCCCTCCTG 
CTAGCTGTGG CAGGAGCCAC TTCTCTGGTG ACCTTGTTGC TGGCGGTGCC TATCACTGTC 
CTGGCTGTGC TGGCCTTAGT GCCCCAGGAT CAGGGAGGAC TGGTAACGGA GACGGCTGAC 
CCCGGGGCAC AGGCCCAGCA AGGACTGGGG TTTCAGAAGC TGCCAGAGGA GGAGCCAGAA 
ACAGATCTCA GCCCCGGGCT CCCAGCTGCC CACCTCATAG GCGCTCCGCT GAAGGGGCAG 
GGGCTAGGCT GGGAGACGAC GAAGGAACAG GCGTTTCTGA CGAGCGGGAC GCAGTTCTCG 
GACGCCGAGG GGCTGGCGCT CCCGCAGGAC GGCCTCTATT ACCTCTACTG TCTCGTCGGC 
TACCGGGGCC GGACGCCCCC TGGCGGCGGG GACCCCCAGG GCCGCTCGGT CACGCTGCGC 
AGCTCTCTGT ACCGGGCGGG GGGCGCCTAC GGGCCGGGCA CTCCCGAGCT GCTGCTCGAG 
GGCGCCGAGA CGGTGACTCC AGTGCTGGAC CCGGCCAGGA GACAAGGGTA CGGGCCTCTC 
TGGTACACGA GCGTGGGGTT CGGCGGCCTG GTGCAGCTCC GGAGGGGCGA GAGGGTGTAC 
GTCAACATCA GTCACCCCGA TATGGTGGAC TTCGCGAGAG GGAAGACCTT CTTTGGGGCC 
GTGATGGTGG GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070252.1
CDS	1..735
Translation	MGALGLEGRGGRLQGRGSLLLAVAGATSLVTLLLAVPITVLAVLALVPQDQGGLVTETADPGAQAQQGLGFQKLPEEEPETDLSPGLPAAHLIGAPLKGQGLGWETTKEQAFLTSGTQFSDAEGLALPQDGLYYLYCLVGYRGRTPPGGGDPQGRSVTLRSSLYRAGGAYGPGTPELLLEGAETVTPVLDPARRQGYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDFARGKTFFGAVMVG

Target ORF information:

RefSeq Version	NM_001076784.1
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes lymphotoxin beta (LTB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001076784.1

ORF Insert Sequence:

ATGGGGGCAC TGGGGCTGGA GGGCAGGGGT GGGAGGCTCC AGGGGAGGGG TTCCCTCCTG 
CTAGCTGTGG CAGGAGCCAC TTCTCTGGTG ACCTTGTTGC TGGCGGTGCC TATCACTGTC 
CTGGCTGTGC TGGCCTTAGT GCCCCAGGAT CAGGGAGGAC TGGTAACGGA GACGGCTGAC 
CCCGGGGCAC AGGCCCAGCA AGGACTGGGG TTTCAGAAGC TGCCAGAGGA GGAGCCAGAA 
ACAGATCTCA GCCCCGGGCT CCCAGCTGCC CACCTCATAG GCGCTCCGCT GAAGGGGCAG 
GGGCTAGGCT GGGAGACGAC GAAGGAACAG GCGTTTCTGA CGAGCGGGAC GCAGTTCTCG 
GACGCCGAGG GGCTGGCGCT CCCGCAGGAC GGCCTCTATT ACCTCTACTG TCTCGTCGGC 
TACCGGGGCC GGACGCCCCC TGGCGGCGGG GACCCCCAGG GCCGCTCGGT CACGCTGCGC 
AGCTCTCTGT ACCGGGCGGG GGGCGCCTAC GGGCCGGGCA CTCCCGAGCT GCTGCTCGAG 
GGCGCCGAGA CGGTGACTCC AGTGCTGGAC CCGGCCAGGA GACAAGGGTA CGGGCCTCTC 
TGGTACACGA GCGTGGGGTT CGGCGGCCTG GTGCAGCTCC GGAGGGGCGA GAGGGTGTAC 
GTCAACATCA GTCACCCCGA TATGGTGGAC TTCGCGAGAG GGAAGACCTT CTTTGGGGCC 
GTGATGGTGG GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
Genetics173(3)1555-70(2006 Jul)
Shiina T,Ota M,Shimizu S,Katsuyama Y,Hashimoto N,Takasu M,Anzai T,Kulski JK,Kikkawa E,Naruse T,Kimura N,Yanagiya K,Watanabe A,Hosomichi K,Kohara S,Iwamoto C,Umehara Y,Meyer A,Wanner V,Sano K,Macquin C,Ikeo K,Tokunaga K,Gojobori T,Inoko H,Bahram S

Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence.
Proceedings of the National Academy of Sciences of the United States of America100(13)7708-13(2003 Jun)
Anzai T,Shiina T,Kimura N,Yanagiya K,Kohara S,Shigenari A,Yamagata T,Kulski JK,Naruse TK,Fujimori Y,Fukuzumi Y,Yamazaki M,Tashiro H,Iwamoto C,Umehara Y,Imanishi T,Meyer A,Ikeo K,Gojobori T,Bahram S,Inoko H

Comparative genomic analysis of the MHC: the evolution of class I duplication blocks, diversity and complexity from shark to man.
Immunological reviews19095-122(2002 Dec)
Kulski JK,Shiina T,Anzai T,Kohara S,Inoko H

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LTB cDNA ORF clone, Pan troglodytes(chimpanzee)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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