Gene Symbol | KIR3DL4 |
Entrez Gene ID | 100125863 |
Full Name | killer cell immunoglobulin-like receptor |
Gene Type | protein-coding |
Organism | Pan troglodytes(chimpanzee) |
ORF » Species Summary » Pan troglodytes » KIR3DL4 cDNA ORF clone
Gene Symbol | KIR3DL4 |
Entrez Gene ID | 100125863 |
Full Name | killer cell immunoglobulin-like receptor |
Gene Type | protein-coding |
Organism | Pan troglodytes(chimpanzee) |
mRNA | Protein | Name |
---|---|---|
NM_001105153.1 | NP_001098623.1 | killer cell immunoglobulin-like receptor precursor |
Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes.
Moesta AK, Abi-Rached L, Norman PJ, Parham P
Journal of immunology (Baltimore, Md. : 1950)182(6)3628-37(2009 Mar)
Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans.
Khakoo SI, Rajalingam R, Shum BP, Weidenbach K, Flodin L, Muir DG, Canavez F, Cooper SL, Valiante NM, Lanier LL, Parham P
Immunity12(6)687-98(2000 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Natural killer leukemia cells expressing chimpanzee-KIR2DL4 cannot kill human carcinoma 221 cells expressing chimpanzee or human MHC-C allotypes bearing the C2 epitope defined by lysine 80.
Title: Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes.
The following KIR3DL4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KIR3DL4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OPc01059 | |
Clone ID Related Accession (Same CDS sequence) | NM_001105153.1 | |
Accession Version | NM_001105153.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-09-20 | |
Organism | Pan troglodytes(chimpanzee) | |
Product | killer cell immunoglobulin-like receptor precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AM400232.1. On Nov 1, 2012 this sequence version replaced XM_003954310.1. ##Evidence-Data-START## Transcript exon combination :: AM400232.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGTCACTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001098623.1 |
CDS | 13..1347 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001105153.1 |
1 | ATGTCACTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes. |
Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans. |