ATIC cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATIC
Entrez Gene ID	396091
Full Name	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms	PURH
General protein information	Preferred Names 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Names bifunctional purine biosynthesis protein PURH 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase, ATIC aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase aminoimidazole-4-carboxamide ribonucleotidetransformylase/IMP cyclohydrolase
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205178.1	NP_990509.1	bifunctional purine biosynthesis protein PURH

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ATIC	XP_001150761.1
Danio rerio (zebrafish)	atic	NP_001076265.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001423	XP_321707.4
Neurospora crassa	NCU02629	XP_964054.1
Homo sapiens (human)	ATIC	NP_004035.2
Drosophila melanogaster (fruit fly)	CG11089	NP_651305.1
Caenorhabditis elegans (roundworm)	C55F2.1	NP_741452.2
Eremothecium gossypii	AGOS_AFR213C	NP_985760.2
Schizosaccharomyces pombe (fission yeast)	ade10	NP_588027.1
Magnaporthe oryzae (rice blast fungus)	MGG_04435	XP_003713530.1
Bos taurus (cattle)	ATIC	NP_001068722.1
Mus musculus (house mouse)	Atic	NP_080471.2
Rattus norvegicus (Norway rat)	Atic	NP_112276.2
Canis lupus familiaris (dog)	ATIC	XP_545634.2
Gallus gallus (chicken)	ATIC	NP_990509.1
Saccharomyces cerevisiae (baker's yeast)	ADE17	NP_013839.1
Xenopus tropicalis (tropical clawed frog)	atic	NP_001005460.1
	LOC694819	XP_002808069.1
Kluyveromyces lactis	KLLA0F17655g	XP_455873.1
Arabidopsis thaliana (thale cress)	AT2G35040	NP_001189681.1
Oryza sativa (rice)	Os08g0206600	NP_001061240.1

Gene Ontology
Bibliography

Related articles in PubMed

Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
Greasley SE, Horton P, Ramcharan J, Beardsley GP, Benkovic SJ, Wilson IA
Nature structural biology8(5)402-6(2001 May)

De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase.
Ni L, Guan K, Zalkin H, Dixon JE
Gene106(2)197-205(1991 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ATIC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATIC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27010	NM_205178.1 Latest version!	Gallus gallus 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATIC ( NM_205178.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990509.1 Gallus gallus 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA.

Price & Availability↑

CloneID	OGa27010
Clone ID Related Accession (Same CDS sequence)	NM_205178.1
Accession Version	NM_205178.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Gallus gallus(chicken)
Product	bifunctional purine biosynthesis protein PURH
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from S64492.1. ##Evidence-Data-START## Transcript exon combination :: S64492.1, AY764168.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCCGCCC GGCAGCAGCT CGCTTTGCTC AGCGTCTCGG AGAAGGCGGG CCTGGTGGAG 
TTCGCCAGGA GCCTGAACGC GTTGGGTCTG GGCCTCATCG CCTCGGGAGG AACGGCCACG 
GCCTTGAGGG ATGCGGGGCT GCCTGTGAGA GATGTTTCGG ACCTGACGGG GTTCCCTGAG 
ATGTTAGGAG GACGTGTGAA AACCCTTCAT CCTGCAGTCC ATGCTGGCAT CTTGGCTCGC 
AATATTCCAG AAGATAACGC TGATATGAAC AAACAAGATT TCAGCCTTGT AAGAGTTGTT 
GTGTGTAACC TCTACCCCTT TGTGAAGACT GTATCTTCTC CGGGTGTAAC TGTACCAGAA 
GCAGTGGAAA AGATTGATAT TGGAGGAGTT GCCTTGCTCC GGGCAGCTGC TAAGAACCAT 
GCTCGTGTGA CAGTTGTGTG TGATCCTGCA GACTACTCTT CTGTAGCTAA AGAGATGGCA 
GCATCGAAGG ACAAAGACAC TTCTGTAGAA ACCAGACGTC ACCTTGCACT GAAGGCTTTC 
ACCCACACTG CTCAGTATGA TGCAGCCATC TCTGACTACT TTAGGAAGGA GTACAGCAAG 
GGGGTGTCCC AGCTGCCCCT GAGGTATGGC ATGAATCCTC ATCAGAGTCC TGCACAGCTC 
TACACCACGA GGCCTAAACT TCCCCTGACA GTGGTGAATG GCTCTCCAGG GTTTATCAAC 
CTGTGTGATG CTCTCAACGC CTGGCAGCTG GTGAAGGAAC TCAAGCAGGC GTTAGGGATC 
CCTGCTGCAG CCTCCTTCAA ACACGTCAGT CCTGCAGGTG CTGCTGTTGG AATACCTCTC 
AGTGAGGAGG AGGCACAAGT CTGCATGGTG CATGATTTAC ACAAGACCTT AACACCCTTG 
GCATCTGCCT ACGCTCGAAG CAGAGGTGCT GATCGGATGT CTTCTTTTGG TGACTTCATT 
GCCTTGTCTG ATATCTGCGA TGTGCCTACT GCTAAGATTA TTTCCAGAGA GGTATCTGAT 
GGTGTGGTAG CTCCTGGCTA TGAGGAAGAA GCTCTCAAAA TCCTTTCCAA AAAGAAGAAT 
GGTGGTTACT GTGTCCTCCA GATGGACCCT AATTATGAGC CAGATGACAA TGAGATTCGA 
ACCCTCTATG GATTGCAGCT CATGCAGAAG AGGAACAATG CAGTCATTGA CCGGTCCTTG 
TTCAAGAACA TTGTTACAAA GAATAAAACT CTGCCTGAGT CTGCTGTCCG AGACCTGATT 
GTTGCCAGCA TTGCTGTCAA ATACACCCAG TCCAACTCAG TGTGCTACGC CAAGGATGGG 
CAGGTCATTG GCATCGGGGC CGGCCAGCAG TCCCGCATCC ACTGCACGCG CCTGGCTGGT 
GACAAGGCCA ACAGCTGGTG GCTGCGGCAC CACCCACGGG TGCTCTCCAT GAAGTTCAAA 
GCAGGAGTGA AGAGAGCAGA GGTCTCCAAC GCCATCGATC AGTACGTCAC TGGCACCATT 
GGAGAGGATG AGGACCTGGT GAAGTGGCAG GCCATGTTTG AAGAGGTGCC CGCACAGCTA 
ACAGAAGCTG AGAAGAAGCA GTGGATTGCC AAGCTGACTG CTGTCTCCCT CAGCTCCGAC 
GCATTCTTCC CTTTTAGGGA TAATGTTGAC AGAGCCAAAC GGATTGGAGT TCAGTTCATC 
GTTGCCCCAT CTGGCTCTGC TGCCGACGAG GTTGTGATTG AAGCTTGCAA TGAGCTGGGA 
ATAACTCTTA TCCACACCAA CCTTCGGCTG TTCCATCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990509.1
CDS	80..1861
Translation	MAARQQLALLSVSEKAGLVEFARSLNALGLGLIASGGTATALRDAGLPVRDVSDLTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMNKQDFSLVRVVVCNLYPFVKTVSSPGVTVPEAVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEMAASKDKDTSVETRRHLALKAFTHTAQYDAAISDYFRKEYSKGVSQLPLRYGMNPHQSPAQLYTTRPKLPLTVVNGSPGFINLCDALNAWQLVKELKQALGIPAAASFKHVSPAGAAVGIPLSEEEAQVCMVHDLHKTLTPLASAYARSRGADRMSSFGDFIALSDICDVPTAKIISREVSDGVVAPGYEEEALKILSKKKNGGYCVLQMDPNYEPDDNEIRTLYGLQLMQKRNNAVIDRSLFKNIVTKNKTLPESAVRDLIVASIAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEVSNAIDQYVTGTIGEDEDLVKWQAMFEEVPAQLTEAEKKQWIAKLTAVSLSSDAFFPFRDNVDRAKRIGVQFIVAPSGSAADEVVIEACNELGITLIHTNLRLFHH

Target ORF information:

RefSeq Version	NM_205178.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205178.1

ORF Insert Sequence:

ATGGCCGCCC GGCAGCAGCT CGCTTTGCTC AGCGTCTCGG AGAAGGCGGG CCTGGTGGAG 
TTCGCCAGGA GCCTGAACGC GTTGGGTCTG GGCCTCATCG CCTCGGGAGG AACGGCCACG 
GCCTTGAGGG ATGCGGGGCT GCCTGTGAGA GATGTTTCGG ACCTGACGGG GTTCCCTGAG 
ATGTTAGGAG GACGTGTGAA AACCCTTCAT CCTGCAGTCC ATGCTGGCAT CTTGGCTCGC 
AATATTCCAG AAGATAACGC TGATATGAAC AAACAAGATT TCAGCCTTGT AAGAGTTGTT 
GTGTGTAACC TCTACCCCTT TGTGAAGACT GTATCTTCTC CGGGTGTAAC TGTACCAGAA 
GCAGTGGAAA AGATTGATAT TGGAGGAGTT GCCTTGCTCC GGGCAGCTGC TAAGAACCAT 
GCTCGTGTGA CAGTTGTGTG TGATCCTGCA GACTACTCTT CTGTAGCTAA AGAGATGGCA 
GCATCGAAGG ACAAAGACAC TTCTGTAGAA ACCAGACGTC ACCTTGCACT GAAGGCTTTC 
ACCCACACTG CTCAGTATGA TGCAGCCATC TCTGACTACT TTAGGAAGGA GTACAGCAAG 
GGGGTGTCCC AGCTGCCCCT GAGGTATGGC ATGAATCCTC ATCAGAGTCC TGCACAGCTC 
TACACCACGA GGCCTAAACT TCCCCTGACA GTGGTGAATG GCTCTCCAGG GTTTATCAAC 
CTGTGTGATG CTCTCAACGC CTGGCAGCTG GTGAAGGAAC TCAAGCAGGC GTTAGGGATC 
CCTGCTGCAG CCTCCTTCAA ACACGTCAGT CCTGCAGGTG CTGCTGTTGG AATACCTCTC 
AGTGAGGAGG AGGCACAAGT CTGCATGGTG CATGATTTAC ACAAGACCTT AACACCCTTG 
GCATCTGCCT ACGCTCGAAG CAGAGGTGCT GATCGGATGT CTTCTTTTGG TGACTTCATT 
GCCTTGTCTG ATATCTGCGA TGTGCCTACT GCTAAGATTA TTTCCAGAGA GGTATCTGAT 
GGTGTGGTAG CTCCTGGCTA TGAGGAAGAA GCTCTCAAAA TCCTTTCCAA AAAGAAGAAT 
GGTGGTTACT GTGTCCTCCA GATGGACCCT AATTATGAGC CAGATGACAA TGAGATTCGA 
ACCCTCTATG GATTGCAGCT CATGCAGAAG AGGAACAATG CAGTCATTGA CCGGTCCTTG 
TTCAAGAACA TTGTTACAAA GAATAAAACT CTGCCTGAGT CTGCTGTCCG AGACCTGATT 
GTTGCCAGCA TTGCTGTCAA ATACACCCAG TCCAACTCAG TGTGCTACGC CAAGGATGGG 
CAGGTCATTG GCATCGGGGC CGGCCAGCAG TCCCGCATCC ACTGCACGCG CCTGGCTGGT 
GACAAGGCCA ACAGCTGGTG GCTGCGGCAC CACCCACGGG TGCTCTCCAT GAAGTTCAAA 
GCAGGAGTGA AGAGAGCAGA GGTCTCCAAC GCCATCGATC AGTACGTCAC TGGCACCATT 
GGAGAGGATG AGGACCTGGT GAAGTGGCAG GCCATGTTTG AAGAGGTGCC CGCACAGCTA 
ACAGAAGCTG AGAAGAAGCA GTGGATTGCC AAGCTGACTG CTGTCTCCCT CAGCTCCGAC 
GCATTCTTCC CTTTTAGGGA TAATGTTGAC AGAGCCAAAC GGATTGGAGT TCAGTTCATC 
GTTGCCCCAT CTGGCTCTGC TGCCGACGAG GTTGTGATTG AAGCTTGCAA TGAGCTGGGA 
ATAACTCTTA TCCACACCAA CCTTCGGCTG TTCCATCACT GA