SOX9 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	SOX9
Entrez Gene ID	374148
Full Name	SRY (sex determining region Y)-box 9
Synonyms	SOX-9
General protein information	Preferred Names SRY (sex determining region Y)-box 9 Names transcription factor SOX-9
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204281.1	NP_989612.1	transcription factor SOX-9

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SOX9	NP_001002978.1
Bos taurus (cattle)	SOX9	XP_005221394.1
Xenopus tropicalis (tropical clawed frog)	sox9	NP_001016853.1
	SOX9	NP_001028040.1
Pan troglodytes (chimpanzee)	SOX9	NP_001009029.1
Mus musculus (house mouse)	Sox9	NP_035578.3
Rattus norvegicus (Norway rat)	Sox9	XP_003750998.1
Gallus gallus (chicken)	SOX9	NP_989612.1
Homo sapiens (human)	SOX9	NP_000337.1
Danio rerio (zebrafish)	sox9a	NP_571718.1

Gene Ontology
Bibliography

Related articles in PubMed

Montero JA, Lorda-Diez CI, Francisco-Morcillo J, Chimal-Monroy J, Garcia-Porrero JA, Hurle JM
Frontiers in cell and developmental biology523(2017)

Mechanical loading stimulates chondrogenesis via the PKA/CREB-Sox9 and PP2A pathways in chicken micromass cultures.
Juh?sz T, Matta C, Somogyi C, Katona ?, Tak?cs R, Soha RF, Szab? IA, Cserh?ti C, Sz?dy R, Kar?csonyi Z, Bak? E, Gergely P, Z?k?ny R
Cellular signalling26(3)468-82(2014 Mar)

Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network.
Sim?es-Costa M, Tan-Cabugao J, Antoshechkin I, Sauka-Spengler T, Bronner ME
Genome research24(2)281-90(2014 Feb)

Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling.
Liu JA, Wu MH, Yan CH, Chau BK, So H, Ng A, Chan A, Cheah KS, Briscoe J, Cheung M
Proceedings of the National Academy of Sciences of the United States of America110(8)2882-7(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Avian digits may represent an evolutionary specialization of digit development consequence of a posterior polarization of signals responsible for limb outgrowth. In contrast, the pentadactyl autopod of mouse and turtle embryos may result from the uniform expansion (like opening a fan) of the signals that coordinate proliferation and differentiation of the skeletal progenitors.

Mechanical stimulation enhances nuclear signals of the transcription factors Sox9 and CREB in a PKA and PP2A-dependent manner
Title: Mechanical loading stimulates chondrogenesis via the PKA/CREB-Sox9 and PP2A pathways in chicken micromass cultures.

The results suggest that ETS1 and SOX9 may act as pan-neural crest regulators of the migratory cranial neural crest
Title: Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network.

data suggest a model in which extracellular signals initiate phosphorylation of Sox9 and its cooperation with Snail2 to induce NCC delamination
Title: Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling.

the balance of Pax3, Nkx3.2 and Sox9 may act as a molecular switch during the chondrogenic differentiation of muscle progenitor cells, which may be important for fracture healing.
Title: Interplay of Nkx3.2, Sox9 and Pax3 regulates chondrogenic differentiation of muscle progenitor cells.

The following SOX9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SOX9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27496	NM_204281.1 Latest version!	Gallus gallus SRY (sex determining region Y)-box 9 (SOX9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SOX9 ( NM_204281.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989612.1 Gallus gallus SRY (sex determining region Y)-box 9 (SOX9), mRNA.

Price & Availability↑

CloneID	OGa27496
Clone ID Related Accession (Same CDS sequence)	NM_204281.1
Accession Version	NM_204281.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Gallus gallus(chicken)
Product	transcription factor SOX-9
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB012236.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB012236.1, U12533.1 [ECO:0000332] ##Evidence-Data-END##

ATGAATCTCC TAGACCCCTT CATGAAAATG ACAGAAGAAC AGGACAAATG CATCTCCGAC 
GCCCCCAGCC CCACCATGTC GGATGACTCC GCCGGGTCCC CCTGCCCCTC CGGATCCGGC 
TCGGACACGG AGAACACCCG ACCTCAAGAG AACACCTTCC CCAAAGGCGA CCCGGACCTG 
AAGAAGGAGA GCGACGAGGA CAAATTCCCC GTGTGCATCC GCGAGGCCGT GAGCCAGGTG 
CTCAAGGGCT ACGACTGGAC CCTGGTGCCC ATGCCCGTGC GGGTGAACGG ATCCAGCAAG 
AACAAACCCC ACGTGAAGCG CCCCATGAAC GCCTTCATGG TGTGGGCCCA GGCGGCTCGA 
AGGAAGCTGG CTGACCAGTA CCCGCATCTG CACAACGCCG AGCTCAGCAA GACGCTGGGC 
AAGCTGTGGA GGCTGCTGAA TGAGAGCGAG AAGCGTCCCT TCGTGGAGGA GGCCGAGCGG 
CTGCGGGTGC AGCACAAGAA GGACCACCCC GACTACAAGT ACCAACCACG CAGGAGGAAG 
TCGGTGAAGA ACGGGCAGTC GGAGCAGGAG GAGGGCTCCG AGCAGACCCA CATCTCCCCC 
AACGCCATCT TCAAGGCGCT GCAGGCGGAC TCCCCGCAGT CATCCTCCAG CATCAGCGAG 
GTGCACTCCC CCGGGGAGCA CTCAGGGCAG TCGCAGGGCC CCCCCACGCC CCCCACCACC 
CCCAAAACGG ACGCTCAGCA GCCGGGCAAG CAGGACCTGA AGCGCGAGGG CCGCCCTTTG 
GCGGAAGGCG GCCGCCAACC TCCCCACATC GATTTCCGAG ACGTGGACAT CGGCGAGCTC 
AGCAGCGACG TCATCTCCAA CATCGAAACC TTCGACGTCA ACGAGTTCGA CCAATACCTG 
CCCCCCAACG GCCACCCGGG GGTCCCGGCC ACCCACGGCC AGGTCACCAC CTACAGCGGT 
ACCTACGGCA TCAGCAGCTC GGCCAGCTCT CCGGCGGGCG CCGGGCACGC CTGGATGGCC 
AAGCAGCAGC CGCAGCCCCC ACAGCCCCCA GCACAGCCCC CGGCACAGCA CACACTGCCA 
GCACTGAGCG GTGAGCAGGG TCCGGCACAG CAGCGGCCGC ACATCAAAAC AGAGCAGCTG 
AGCCCCAGCC ACTACAGCGA GCAGCAGCAG CACTCCCCGC AGCAGCAGCA GCAGCAGCAA 
CAGCAGCTGG GCTACGGCTC CTTCAACCTG CAGCACTACG GCTCCTCGTA CCCCCCCATC 
ACCCGCTCGC AGTACGATTA CACCGAGCAC CAGAACTCCG GCTCCTACTA CAGCCACGCC 
GCCGGGCAGA GCGGAGGCCT CTACTCCACC TTCACCTACA TGAACCCCAC GCAGCGCCCC 
ATGTACACCC CCATCGCAGA CACGTCGGGG GTGCCCTCTA TCCCGCAGAC CCACAGCCCG 
CAGCACTGGG AACAGCCCGT CTACACGCAG CTCACCCGGC CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989612.1
CDS	117..1601
Translation	MNLLDPFMKMTEEQDKCISDAPSPTMSDDSAGSPCPSGSGSDTENTRPQENTFPKGDPDLKKESDEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQSEQEEGSEQTHISPNAIFKALQADSPQSSSSISEVHSPGEHSGQSQGPPTPPTTPKTDAQQPGKQDLKREGRPLAEGGRQPPHIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTTYSGTYGISSSASSPAGAGHAWMAKQQPQPPQPPAQPPAQHTLPALSGEQGPAQQRPHIKTEQLSPSHYSEQQQHSPQQQQQQQQQLGYGSFNLQHYGSSYPPITRSQYDYTEHQNSGSYYSHAAGQSGGLYSTFTYMNPTQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP

Target ORF information:

RefSeq Version	NM_204281.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus SRY (sex determining region Y)-box 9 (SOX9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204281.1

ORF Insert Sequence:

ATGAATCTCC TAGACCCCTT CATGAAAATG ACAGAAGAAC AGGACAAATG CATCTCCGAC 
GCCCCCAGCC CCACCATGTC GGATGACTCC GCCGGGTCCC CCTGCCCCTC CGGATCCGGC 
TCGGACACGG AGAACACCCG ACCTCAAGAG AACACCTTCC CCAAAGGCGA CCCGGACCTG 
AAGAAGGAGA GCGACGAGGA CAAATTCCCC GTGTGCATCC GCGAGGCCGT GAGCCAGGTG 
CTCAAGGGCT ACGACTGGAC CCTGGTGCCC ATGCCCGTGC GGGTGAACGG ATCCAGCAAG 
AACAAACCCC ACGTGAAGCG CCCCATGAAC GCCTTCATGG TGTGGGCCCA GGCGGCTCGA 
AGGAAGCTGG CTGACCAGTA CCCGCATCTG CACAACGCCG AGCTCAGCAA GACGCTGGGC 
AAGCTGTGGA GGCTGCTGAA TGAGAGCGAG AAGCGTCCCT TCGTGGAGGA GGCCGAGCGG 
CTGCGGGTGC AGCACAAGAA GGACCACCCC GACTACAAGT ACCAACCACG CAGGAGGAAG 
TCGGTGAAGA ACGGGCAGTC GGAGCAGGAG GAGGGCTCCG AGCAGACCCA CATCTCCCCC 
AACGCCATCT TCAAGGCGCT GCAGGCGGAC TCCCCGCAGT CATCCTCCAG CATCAGCGAG 
GTGCACTCCC CCGGGGAGCA CTCAGGGCAG TCGCAGGGCC CCCCCACGCC CCCCACCACC 
CCCAAAACGG ACGCTCAGCA GCCGGGCAAG CAGGACCTGA AGCGCGAGGG CCGCCCTTTG 
GCGGAAGGCG GCCGCCAACC TCCCCACATC GATTTCCGAG ACGTGGACAT CGGCGAGCTC 
AGCAGCGACG TCATCTCCAA CATCGAAACC TTCGACGTCA ACGAGTTCGA CCAATACCTG 
CCCCCCAACG GCCACCCGGG GGTCCCGGCC ACCCACGGCC AGGTCACCAC CTACAGCGGT 
ACCTACGGCA TCAGCAGCTC GGCCAGCTCT CCGGCGGGCG CCGGGCACGC CTGGATGGCC 
AAGCAGCAGC CGCAGCCCCC ACAGCCCCCA GCACAGCCCC CGGCACAGCA CACACTGCCA 
GCACTGAGCG GTGAGCAGGG TCCGGCACAG CAGCGGCCGC ACATCAAAAC AGAGCAGCTG 
AGCCCCAGCC ACTACAGCGA GCAGCAGCAG CACTCCCCGC AGCAGCAGCA GCAGCAGCAA 
CAGCAGCTGG GCTACGGCTC CTTCAACCTG CAGCACTACG GCTCCTCGTA CCCCCCCATC 
ACCCGCTCGC AGTACGATTA CACCGAGCAC CAGAACTCCG GCTCCTACTA CAGCCACGCC 
GCCGGGCAGA GCGGAGGCCT CTACTCCACC TTCACCTACA TGAACCCCAC GCAGCGCCCC 
ATGTACACCC CCATCGCAGA CACGTCGGGG GTGCCCTCTA TCCCGCAGAC CCACAGCCCG 
CAGCACTGGG AACAGCCCGT CTACACGCAG CTCACCCGGC CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Frontiers in cell and developmental biology523(2017)
Montero JA,Lorda-Diez CI,Francisco-Morcillo J,Chimal-Monroy J,Garcia-Porrero JA,Hurle JM

Mechanical loading stimulates chondrogenesis via the PKA/CREB-Sox9 and PP2A pathways in chicken micromass cultures.
Cellular signalling26(3)468-82(2014 Mar)
Juh?sz T,Matta C,Somogyi C,Katona ?,Tak?cs R,Soha RF,Szab? IA,Cserh?ti C,Sz?dy R,Kar?csonyi Z,Bak? E,Gergely P,Z?k?ny R

Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network.
Genome research24(2)281-90(2014 Feb)
Sim?es-Costa M,Tan-Cabugao J,Antoshechkin I,Sauka-Spengler T,Bronner ME

Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling.
Proceedings of the National Academy of Sciences of the United States of America110(8)2882-7(2013 Feb)
Liu JA,Wu MH,Yan CH,Chau BK,So H,Ng A,Chan A,Cheah KS,Briscoe J,Cheung M

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SOX9 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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