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Drosophila melanogaster (fruit fly)

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Pyrimidine metabolism Synthesis and interconversion of nucleotide di- and triphosphates
Vitamin C (ascorbate) metabolism Vitamin B5 (pantothenate) metabolism
Nicotinate metabolism Metabolism of vitamin K
Metabolism of amino acids and derivatives Metabolism of polyamines
Metabolism of ingested SeMet, Sec, MeSec into H2Se Heme biosynthesis
Biological oxidations Xenobiotics
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Ethanol oxidation
Glucuronidation Methylation
Glutathione synthesis and recycling O2/CO2 exchange in erythrocytes
Erythrocytes take up carbon dioxide and release oxygen Abacavir metabolism
DSCAM interactions Vesicle-mediated transport
Endosomal Sorting Complex Required For Transport (ESCRT) Bicarbonate transporters
Facilitative Na+-independent glucose transporters Inositol transporters
Zinc influx into cells by the SLC39 gene family Organic cation/anion/zwitterion transport
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Iron uptake and transport
Formation of the cornified envelope MET activates PTK2 signaling
MET activates RAP1 and RAC1 Miscellaneous digestion events
SUMOylation of chromatin organization proteins Neutrophil degranulation
Phosphate bond hydrolysis by NTPDase proteins Pyrophosphate hydrolysis
GRB2 events in ERBB2 signaling Disassembly of the destruction complex and recruitment of AXIN to the membrane
Cargo recognition for clathrin-mediated endocytosis Negative regulation of activity of TFAP2 (AP-2) family transcription factors
O-linked glycosylation of mucins UCH proteinases
Ub-specific processing proteases Apoptotic execution phase
Apoptosis induced DNA fragmentation Regulation of necroptotic cell death
Signal Transduction RAF/MAP kinase cascade
RAF activation SHC1 events in EGFR signaling
AKT phosphorylates targets in the cytosol AKT phosphorylates targets in the nucleus
Negative regulation of the PI3K/AKT network Signaling by FGFR1
Spry regulation of FGF signaling FGFR2 alternative splicing
Downstream signaling of activated FGFR2 PI-3K cascade:FGFR2
FGFR3 ligand binding and activation FGFR3b ligand binding and activation
FGFR3c ligand binding and activation Phospholipase C-mediated cascade; FGFR3
Signaling by FGFR4 Phospholipase C-mediated cascade; FGFR4
Signaling by Insulin receptor IRS-mediated signalling
Inhibition of TSC complex formation by PKB Cell death signalling via NRAGE, NRIF and NADE
NF-kB is activated and signals survival Axonal growth inhibition (RHOA activation)
Signalling to p38 via RIT and RIN Frs2-mediated activation
PLC-gamma1 signalling Signaling by ERBB2
SHC1 events in ERBB2 signaling MAPK family signaling cascades
RHO GTPase Effectors GPCR ligand binding
Muscarinic acetylcholine receptors Nucleotide-like (purinergic) receptors
Opsins G alpha (z) signalling events
G alpha (12/13) signalling events G-protein activation
DARPP-32 events Beta-catenin phosphorylation cascade
Repression of WNT target genes Formation of the beta-catenin:TCF transactivating complex
Asymmetric localization of PCP proteins The retinoid cycle in cones (daylight vision)
Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
GRB2:SOS provides linkage to MAPK signaling for Integrins Signaling by Hedgehog
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases PTK6 Regulates Proteins Involved in RNA Processing
GPVI-mediated activation cascade Response to elevated platelet cytosolic Ca2+
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