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Drosophila melanogaster (fruit fly)

Browse by Letter Index, Genomic Locus


PKA activation Cam-PDE 1 activation
Regulation of RAS by GAPs SHC-mediated cascade:FGFR1
FGFR2 ligand binding and activation FGFR2b ligand binding and activation
Phospholipase C-mediated cascade; FGFR2 SHC-mediated cascade:FGFR2
FRS-mediated FGFR4 signaling Insulin receptor signalling cascade
PI3K Cascade mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK SOS-mediated signalling
p75 NTR receptor-mediated signalling NGF signalling via TRKA from the plasma membrane
ARMS-mediated activation Nuclear Events (kinase and transcription factor activation)
ERK/MAPK targets ERKs are inactivated
PI3K events in ERBB4 signaling RAF-independent MAPK1/3 activation
Downregulation of TGF-beta receptor signaling Peptide ligand-binding receptors
GPCR downstream signaling Adenylate cyclase inhibitory pathway
Degradation of beta-catenin by the destruction complex Deactivation of the beta-catenin transactivating complex
Degradation of DVL Degradation of AXIN
IGF1R signaling cascade Signaling by Activin
Antagonism of Activin by Follistatin Visual phototransduction
RA biosynthesis pathway Integrin alphaIIb beta3 signaling
p130Cas linkage to MAPK signaling for integrins Platelet homeostasis
Reduction of cytosolic Ca++ levels Basigin interactions
Factors involved in megakaryocyte development and platelet production DNA Replication
Assembly of the pre-replicative complex CDT1 association with the CDC6:ORC:origin complex
DNA replication initiation CDK-mediated phosphorylation and removal of Cdc6
Polymerase switching Lagging Strand Synthesis
Association of licensing factors with the pre-replicative complex Semaphorin interactions
Inactivation of Cdc42 and Rac Signal transduction by L1
EPH-Ephrin signaling Transcriptional activation of mitochondrial biogenesis
Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle
Degradation of GABA Serotonin clearance from the synaptic cleft
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Postsynaptic nicotinic acetylcholine receptors
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity CREB phosphorylation through the activation of Adenylate Cyclase
Ionotropic activity of Kainate Receptors Activation of Na-permeable Kainate Receptors
Inhibition of adenylate cyclase pathway TWIK-related alkaline pH activated K+ channel (TALK)
SALM protein interactions at the synapses Ion homeostasis
Synthesis of diphthamide-EEF2 Post-translational modification: synthesis of GPI-anchored proteins
Synthesis of dolichyl-phosphate-glucose N-Glycan antennae elongation
SUMO E3 ligases SUMOylate target proteins Peptide hormone metabolism
Unfolded Protein Response (UPR) ATF6 (ATF6-alpha) activates chaperones
Protein repair Immune System
Costimulation by the CD28 family Signaling by the B Cell Receptor (BCR)
Downstream signaling events of B Cell Receptor (BCR) Class I MHC mediated antigen processing & presentation
Cross-presentation of soluble exogenous antigens (endosomes) Rap1 signalling
IRAK1 recruits IKK complex MAP kinase activation in TLR cascade
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 MAPK targets/ Nuclear events mediated by MAP kinases
Activation of the AP-1 family of transcription factors TRAF6 mediated induction of TAK1 complex
Toll Like Receptor 7/8 (TLR7/8) Cascade TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways RIP-mediated NFkB activation via ZBP1
STAT6-mediated induction of chemokines LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
DAP12 interactions DAP12 signaling
Fc epsilon receptor (FCERI) signaling FCERI mediated MAPK activation
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