Gene Symbol | ain-1 |
Entrez Gene ID | 181719 |
Full Name | ALG-1 INteracting protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » ain-1 cDNA ORF clone
Gene Symbol | ain-1 |
Entrez Gene ID | 181719 |
Full Name | ALG-1 INteracting protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_078286.6 | NP_510687.2 | ALG-1 INteracting protein |
NM_078286.5 | NP_510687.2 | ALG-1 INteracting protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We show in vitro and in vivo that their mutations severely altered the association with AIN-1 and AIN-2. our results demonstrate that the microRNA pathway can act independently of GW182 proteins during C. elegans embryogenesis
Title: GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis.
AIN-1 is selectively degraded by autophagy.
Title: Autophagy modulates miRNA-mediated gene silencing and selectively degrades AIN-1/GW182 in C. elegans.
AIN-1 interacts with Argonaute proteins through GW repeats in the middle region of the protein.
Title: The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes.
let-7 represses translation initiation in Caenorhabditis elegans which requires the GW182 proteins AIN-1 and AIN-2.
Title: Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins.
GW182 family proteins AIN-1 and AIN-2 act redundantly to regulate the expression of miRNA targets, but not miRNA biogenesis.
Title: Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.
The following ain-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ain-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349219 | |
Clone ID Related Accession (Same CDS sequence) | NM_078286.6 , NM_078286.5 | |
Accession Version | NM_078286.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | ALG-1 INteracting protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_078286.5. |
1 | ATGGAGAGTC TCGCAAAAAA CTTCAACAAC ATTTCAATAG ACGACGCAGC GTGGCATCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_510687.2 |
CDS | 43..1968 |
Translation |
Target ORF information:
Target ORF information:
|
NM_078286.6 |
1 | ATGGAGAGTC TCGCAAAAAA CTTCAACAAC ATTTCAATAG ACGACGCAGC GTGGCATCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349219 | |
Clone ID Related Accession (Same CDS sequence) | NM_078286.6 , NM_078286.5 | |
Accession Version | NM_078286.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | ALG-1 INteracting protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_078286.4. COMPLETENESS: incomplete on both ends. |
1 | ATGGAGAGTC TCGCAAAAAA CTTCAACAAC ATTTCAATAG ACGACGCAGC GTGGCATCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_510687.2 |
CDS | 1..1926 |
Translation |
Target ORF information:
Target ORF information:
|
NM_078286.5 |
1 | ATGGAGAGTC TCGCAAAAAA CTTCAACAAC ATTTCAATAG ACGACGCAGC GTGGCATCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |