Gene Symbol | mdl-1 |
Entrez Gene ID | 180942 |
Full Name | MAD-Like |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » mdl-1 cDNA ORF clone
Gene Symbol | mdl-1 |
Entrez Gene ID | 180942 |
Full Name | MAD-Like |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_076735.6 | NP_509136.1 | BHLH domain-containing protein |
NM_076735.5 | NP_509136.1 | MAD-Like |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The Mad-like transcription factor MDL-1, and the Max-like transcription factors MXL-1 and MXL-2 promote pathogen levels, while the Myc-Mondo-like transcription factor MML-1 inhibits pathogen levels. We used epistasis analysis to show that MDL-1 and MXL-1, which are thought to function as a heterodimer, appear to be acting canonically.
Title: Microsporidia Intracellular Development Relies on Myc Interaction Network Transcription Factors in the Host.
The MML-1:MXL-2 and MDL-1:MXL-1 complexes function in both the insulin signaling and dietary restriction pathways.
Title: The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals.
likely acts both in the intestine and the germline to influence age-related mortality
Title: MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans.
The following mdl-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mdl-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349921 | |
Clone ID Related Accession (Same CDS sequence) | NM_076735.6 , NM_076735.5 | |
Accession Version | NM_076735.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | BHLH domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_076735.5. |
1 | ATGGAACAGC AACTCAACCT TGGACATCTT CTCACCGCCG CACGTCTTTT AGACATTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509136.1 |
CDS | 136..981 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076735.6 |
1 | ATGGAACAGC AACTCAACCT TGGACATCTT CTCACCGCCG CACGTCTTTT AGACATTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349921 | |
Clone ID Related Accession (Same CDS sequence) | NM_076735.6 , NM_076735.5 | |
Accession Version | NM_076735.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | MAD-Like | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_076735.4. COMPLETENESS: incomplete on both ends. |
1 | ATGGAACAGC AACTCAACCT TGGACATCTT CTCACCGCCG CACGTCTTTT AGACATTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509136.1 |
CDS | 1..846 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076735.5 |
1 | ATGGAACAGC AACTCAACCT TGGACATCTT CTCACCGCCG CACGTCTTTT AGACATTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |