Gene Symbol | nphp-1 |
Entrez Gene ID | 174643 |
Full Name | Nephrocystin-1-like protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » nphp-1 cDNA ORF clone
Gene Symbol | nphp-1 |
Entrez Gene ID | 174643 |
Full Name | Nephrocystin-1-like protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_063897.4 | NP_496298.1 | Nephrocystin-1-like protein |
NM_063897.5 | NP_496298.1 | Nephrocystin-1-like protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The C. elegans B9 proteins form a complex that localizes to the base of cilia. Mutations in the B9 genes do not overtly affect cilia formation unless they are in combination with a mutation in nph-1 or nph-4.
Title: Functional redundancy of the B9 proteins and nephrocystins in Caenorhabditis elegans ciliogenesis.
We propose that NPHP-1 and NPHP-4 act globally at the TZ to regulate ciliary access of the IFT machinery, axonemal structural components, and signaling molecules, and that perturbing this balance results in cell type-specific phenotypes.
Title: The Caenorhabditis elegans nephrocystins act as global modifiers of cilium structure.
NPHP-1 and NPHP-4 proteins play important and redundant roles in facilitating ciliary sensory signal transduction.
Title: Functional characterization of the C. elegans nephrocystins NPHP-1 and NPHP-4 and their role in cilia and male sensory behaviors.
The NPHP homologs may be necessary for initial assembly of the cilium, whereas the polycystic kidney disease homologs may function as sensory transducers.
Title: Expression and phenotype analysis of the nephrocystin-1 and nephrocystin-4 homologs in Caenorhabditis elegans.
The following nphp-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nphp-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa339730 | |
Clone ID Related Accession (Same CDS sequence) | NM_063897.4 , NM_063897.5 | |
Accession Version | NM_063897.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2049bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nephrocystin-1-like protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_063897.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTCCATAT TTGGAAGCAT TCTAAGTCTG CAGGATGCCA TAAATCGATT TCCGCAGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_496298.1 |
CDS | 1..2049 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063897.4 |
1 | ATGTCCATAT TTGGAAGCAT TCTAAGTCTG CAGGATGCCA TAAATCGATT TCCGCAGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339730 | |
Clone ID Related Accession (Same CDS sequence) | NM_063897.4 , NM_063897.5 | |
Accession Version | NM_063897.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2049bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nephrocystin-1-like protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_063897.4. |
1 | ATGTCCATAT TTGGAAGCAT TCTAAGTCTG CAGGATGCCA TAAATCGATT TCCGCAGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_496298.1 |
CDS | 28..2076 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063897.5 |
1 | ATGTCCATAT TTGGAAGCAT TCTAAGTCTG CAGGATGCCA TAAATCGATT TCCGCAGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |