Gene Symbol | lin-28 |
Entrez Gene ID | 172626 |
Full Name | Protein lin-28 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » lin-28 cDNA ORF clone
Gene Symbol | lin-28 |
Entrez Gene ID | 172626 |
Full Name | Protein lin-28 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001025914.4 | NP_001021085.1 | Protein lin-28 |
NM_001025914.5 | NP_001021085.1 | Protein lin-28 |
NM_059880.6 | NP_492281.2 | Protein lin-28 |
NM_059880.5 | NP_492281.2 | Protein lin-28 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
show that CED-3 caspase and the E3 ubiquitin ligase UBR-1 form a complex that couples their in vivo activities, allowing for recognition and rapid degradation of LIN-28 and thus facilitating a switch in developmental programs
Title: Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development.
LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans
Title: Makorin ortholog LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans.
LIN-28 regulates the expression of the let-7 microRNA by binding its primary transcript in a previously unknown region, revealing a novel regulatory mechanism.
Title: A novel mechanism of LIN-28 regulation of let-7 microRNA expression revealed by in vivo HITS-CLIP in C. elegans.
lin-28's two-step mechanism may be an essential feature of its evolutionarily conserved role in cell fate succession
Title: lin-28 controls the succession of cell fate choices via two distinct activities.
LIN28 can directly inhibit let-7g biogenesis at the Dicer processing step
Title: A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing.
The following lin-28 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lin-28 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336313 | |
Clone ID Related Accession (Same CDS sequence) | NM_001025914.4 , NM_001025914.5 | |
Accession Version | NM_001025914.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein lin-28 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_001025914.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGACGG TAGTATCGGA GGGAAGGAAT GATGGGAATA ACCGATATTC ACCACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021085.1 |
CDS | 1..684 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001025914.4 |
1 | ATGTCGACGG TAGTATCGGA GGGAAGGAAT GATGGGAATA ACCGATATTC ACCACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336313 | |
Clone ID Related Accession (Same CDS sequence) | NM_001025914.4 , NM_001025914.5 | |
Accession Version | NM_001025914.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein lin-28 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001025914.4. |
1 | ATGTCGACGG TAGTATCGGA GGGAAGGAAT GATGGGAATA ACCGATATTC ACCACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021085.1 |
CDS | 2..685 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001025914.5 |
1 | ATGTCGACGG TAGTATCGGA GGGAAGGAAT GATGGGAATA ACCGATATTC ACCACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336314 | |
Clone ID Related Accession (Same CDS sequence) | NM_059880.6 , NM_059880.5 | |
Accession Version | NM_059880.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 591bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein lin-28 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059880.5. |
1 | ATGATTGAAG CCGCTTTGGA GAATCCGGTG CCCATCAAAT CTCAATTGTC ACCAACACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492281.2 |
CDS | 190..780 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059880.6 |
1 | ATGATTGAAG CCGCTTTGGA GAATCCGGTG CCCATCAAAT CTCAATTGTC ACCAACACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336314 | |
Clone ID Related Accession (Same CDS sequence) | NM_059880.6 , NM_059880.5 | |
Accession Version | NM_059880.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 591bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein lin-28 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059880.4. COMPLETENESS: incomplete on both ends. |
1 | ATGATTGAAG CCGCTTTGGA GAATCCGGTG CCCATCAAAT CTCAATTGTC ACCAACACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492281.2 |
CDS | 1..591 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059880.5 |
1 | ATGATTGAAG CCGCTTTGGA GAATCCGGTG CCCATCAAAT CTCAATTGTC ACCAACACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |