Gene Symbol | YPT7 |
Entrez Gene ID | 855012 |
Full Name | Rab family GTPase YPT7 |
Synonyms | AST4,VAM4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » YPT7 cDNA ORF clone
Gene Symbol | YPT7 |
Entrez Gene ID | 855012 |
Full Name | Rab family GTPase YPT7 |
Synonyms | AST4,VAM4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182356.1 | NP_013713.1 | Rab family GTPase YPT7 |
RAB7A | XP_001095709.2 | |
Gallus gallus (chicken) | RAB7A | XP_003642026.1 |
Danio rerio (zebrafish) | rab7 | NP_957222.1 |
Eremothecium gossypii | AGOS_ACR003C | NP_983406.1 |
Schizosaccharomyces pombe (fission yeast) | ypt7 | NP_596307.1 |
Xenopus tropicalis (tropical clawed frog) | rab7a | NP_001008026.1 |
Canis lupus familiaris (dog) | RAB7A | NP_001003316.1 |
Saccharomyces cerevisiae (baker's yeast) | YPT7 | NP_013713.1 |
Neurospora crassa | NCU03711 | XP_961487.1 |
Arabidopsis thaliana (thale cress) | RABG3E | NP_001031161.1 |
Pan troglodytes (chimpanzee) | RAB7A | XP_003950230.1 |
Mus musculus (house mouse) | Rab7 | NP_033031.2 |
Rattus norvegicus (Norway rat) | Rab7a | NP_076440.1 |
Arabidopsis thaliana (thale cress) | RAB7B | NP_188512.1 |
Homo sapiens (human) | RAB7A | NP_004628.4 |
Bos taurus (cattle) | RAB7A | NP_001030253.1 |
Kluyveromyces lactis | KLLA0D01265g | XP_453125.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08144 | XP_003715107.1 |
Oryza sativa (rice) | Os05g0516600 | NP_001056046.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Homotypic fusion and protein-sorting/class C vacuole protein-sorting (HOPS/class C Vps) complex can tether low-curvature membranes, that is, liposomes with a diameter of 100 nm, only when the yeast vacuolar Ypt7p is present in both tethered membranes.
Title: The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane.
Guanine nucleotide exchange factor activity of the Mon1-Ccz1 complex towards Ypt7 requires the interface formed by their longin domains.
Title: The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes.
phosphorylation of vacuole protein sorting complex (HOPS) by recombinant Yck3p confers strict requirement for GTP-bound Ypt7p for binding phosphorylated HOPS, for optimal membrane tethering and proteoliposome fusion; guanine nucleotide specificity of the vacuolar fusion Rab Ypt7p is conferred through downstream posttranslational modification of its effector complex
Title: Phosphorylation of the effector complex HOPS by the vacuolar kinase Yck3p confers Rab nucleotide specificity for vacuole docking and fusion.
yeast retromer trimer antagonizes Ypt7-regulated organelle tethering and fusion of endosomes/vacuoles via recognition of Ypt7
Title: Rab GTPase regulation of retromer-mediated cargo export during endosome maturation.
msb3 vacuoles fuse more efficiently than wild-type vacuoles in vitro, suggesting that GAP can also act on Ypt7
Title: The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles.
The following YPT7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the YPT7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04000 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182356.1 | |
Accession Version | NM_001182356.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Rab family GTPase YPT7 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTTCTA GAAAAAAAAA TATTTTGAAA GTAATCATCC TAGGTGACTC TGGTGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013713.1 |
CDS | 1..627 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTCTTCTA GAAAAAAAAA TATTTTGAAA GTAATCATCC TAGGTGACTC TGGTGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |