Gene Symbol | SBA1 |
Entrez Gene ID | 853743 |
Full Name | Hsp90 cochaperone SBA1 |
Synonyms | CST18 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SBA1 cDNA ORF clone
Gene Symbol | SBA1 |
Entrez Gene ID | 853743 |
Full Name | Hsp90 cochaperone SBA1 |
Synonyms | CST18 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179683.1 | NP_012805.1 | Hsp90 cochaperone SBA1 |
Kluyveromyces lactis | KLLA0C14322g | XP_452841.1 |
Schizosaccharomyces pombe (fission yeast) | wos2 | NP_594586.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06669 | XP_003709374.1 |
Saccharomyces cerevisiae (baker's yeast) | SBA1 | NP_012805.1 |
Eremothecium gossypii | AGOS_ABL057W | NP_982890.1 |
Neurospora crassa | NCU01792 | XP_956470.2 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome XI.
Dujon B, Alexandraki D, Andr? B, Ansorge W, Baladron V, Ballesta JP, Banrevi A, Bolle PA, Bolotin-Fukuhara M, Bossier P, Bou G, Boyer J, Bultrago MJ, Cheret G, Colleaux L, Dalgnan-Fornler B, del Rey F, Dlon C, Domdey H, D?sterhoft A, D?sterhus S, Entlan KD, Erfle H, Esteban PF, Feldmann H, Fernandes L, Robo GM, Fritz C, Fukuhara H, Gabel C, Gaillon L, Carcia-Cantalejo JM, Garcia-Ramirez JJ, Gent NE, Ghazvini M, Goffeau A, Gonzal?z A, Grothues D, Guerreiro P, Hegemann J, Hewitt N, Hilger F, Hollenberg CP, Horaitis O, Indge KJ, Jacquier A, James CM, Jauniaux C, Jimenez A, Keuchel H, Kirchrath L, Kleine K, K?tter P, Legrain P, Liebl S, Louis EJ, Maia e Silva A, Marck C, Monnier AL, M?stl D, M?ller S, Obermaier B, Oliver SG, Pallier C, Pascolo S, Pfeiffer F, Philippsen P, Planta RJ, Pohl FM, Pohl TM, P?hlmann R, Portetelle D, Purnelle B, Puzos V, Ramezani Rad M, Rasmussen SW, Remacha M, Revuelta JL, Richard GF, Rieger M, Rodrigues-Pousada C, Rose M, Rupp T, Santos MA, Schwager C, Sensen C, Skala J, Soares H, Sor F, Stegemann J, Tettelin H, Thierry A, Tzermia M, Urrestarazu LA, van Dyck L, Van Vliet-Reedijk JC, Valens M, Vandenbo M, Vilela C, Vissers S, von Wettstein D, Voss H, Wiemann S, Xu G, Zimmermann J, Haasemann M, Becker I, Mewes HW
Nature369(6479)371-8(1994 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data support a model in which p23 molecular chaperone and GCN5 regulate diverse multistep pathways by controlling the longevity of protein-DNA complexes.
Title: The p23 molecular chaperone and GCN5 acetylase jointly modulate protein-DNA dynamics and open chromatin status.
Structure-function analysis suggests that Sba1p undergoes structural rearrangements upon binding Hsp90, and the large size of the p23/Sba1p-Hsp90 interaction surface facilitates maintenance of high affinity despite sequence divergence during evolution.
Title: p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity.
SBA1 is required for teleomere length maintenance. It can moderate telomerase DNA binding and extension activities in vitro.
Title: The p23 molecular chaperone promotes functional telomerase complexes through DNA dissociation.
crystal structure of full-length yeast Hsp90 in complex with an ATP analogue and the co-chaperone p23/Sba1
Title: Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex.
The following SBA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SBA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02948 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179683.1 | |
Accession Version | NM_001179683.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Hsp90 cochaperone SBA1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001143). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCCGATA AAGTTATTAA CCCTCAAGTT GCATGGGCTC AAAGGTCTAG TACTACTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012805.1 |
CDS | 1..651 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTCCGATA AAGTTATTAA CCCTCAAGTT GCATGGGCTC AAAGGTCTAG TACTACTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome XI. |