Gene Symbol | FAR1 |
Entrez Gene ID | 853283 |
Full Name | cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » FAR1 cDNA ORF clone
Gene Symbol | FAR1 |
Entrez Gene ID | 853283 |
Full Name | cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181590.1 | NP_012378.1 | cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat JC, Coster F, Cziepluch C, De Haan M, Domdey H, Durand P, Entian KD, Gatius M, Goffeau A, Grivell LA, Hennemann A, Herbert CJ, Heumann K, Hilger F, Hollenberg CP, Huang ME, Jacq C, Jauniaux JC, Katsoulou C, Karpfinger-Hartl L
The EMBO journal15(9)2031-49(1996 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This papers suggests that Far1 engages the cyclin-Cdk complex in a way that disrupts multiple distinct functions, including both substrate docking and kinase activity but perhaps also others such as Cks1-mediated processivity.
Title: Regulation of cyclin-substrate docking by a G1 arrest signaling pathway and the Cdk inhibitor Far1.
Studied FAR1 overexpression, which not only coordinately increases RNA and protein accumulation, but induces strong transcriptional remodeling.
Title: Overexpression of Far1, a cyclin-dependent kinase inhibitor, induces a large transcriptional reprogramming in which RNA synthesis senses Far1 in a Sfp1-mediated way.
Cln3 must overcome Far1 to trigger Cln-Cdc28 activation, which then turns on transcription; a second threshold is required together with the Cln3/Far1 threshold for carbon source modulation of protein content per cell at the onset of DNA replication
Title: A cell sizer network involving Cln3 and Far1 controls entrance into S phase in the mitotic cycle of budding yeast.
Gbetagamma not only targets Far1p to the correct site but may also trigger a conformational change in Far1p that is required for its ability to activate Cdc24p in vivo
Title: Site-specific regulation of the GEF Cdc24p by the scaffold protein Far1p during yeast mating.
The following FAR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02562 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181590.1 | |
Accession Version | NM_001181590.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2493bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001142). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAAGACAC CAACAAGAGT TTCGTTTGAA AAAAAAATAC ACACTCCACC AAGTGGAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012378.1 |
CDS | 1..2493 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181590.1 |
1 | ATGAAGACAC CAACAAGAGT TTCGTTTGAA AAAAAAATAC ACACTCCACC AAGTGGAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. |