Gene Symbol | SLD3 |
Entrez Gene ID | 852765 |
Full Name | Sld3p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SLD3 cDNA ORF clone
Gene Symbol | SLD3 |
Entrez Gene ID | 852765 |
Full Name | Sld3p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180978.3 | NP_011402.3 | Sld3p |
Eremothecium gossypii | AGOS_AFL019C | NP_985529.1 |
Saccharomyces cerevisiae (baker's yeast) | SLD3 | NP_011402.3 |
Kluyveromyces lactis | KLLA0F10681g | XP_455566.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Sld3 binds specifically to DDK-phosphorylated peptides from two MCM subunits (Mcm4, 6) and then recruits Cdc45.
Title: Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation.
Here, the crystal structure of Sld7 in complex with Sld3 is presented. Sld7 comprises two structural domains.
Title: The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3.
The crystal structure of the central domain of Sld3 from Saccharomyces cerevisiae.
Title: Crystal structure of the homology domain of the eukaryotic DNA replication proteins Sld3/Treslin.
The low-abundance replication proteins Sld3, Sld7, and Cdc45 form a complex and associate with the early-firing origins in G1 phase in a manner that depends on Dbf4-dependent kinase (DDK), which is essential for the initiation of DNA replication.
Title: Origin association of Sld3, Sld7, and Cdc45 proteins is a key step for determination of origin-firing timing.
CDK substrates Sld3 and Sld2 and their binding partner Dpb11, together with the DDK subunit Dbf4 control S-phase length in budding yeast Saccharomyces cerevisiae limiting replication initiationst hrough their low abundance.
Title: Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast.
The following SLD3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLD3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02134 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180978.3 | |
Accession Version | NM_001180978.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2007bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Sld3p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). On Jul 30, 2012 this sequence version replaced NM_001180978.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAAACAT GGGAAGTCAT AGCATCGGTA AAAGAAGCAA CAAAAGGCCT TGACTTGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011402.3 |
CDS | 1..2007 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180978.3 |
1 | ATGGAAACAT GGGAAGTCAT AGCATCGGTA AAAGAAGCAA CAAAAGGCCT TGACTTGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |