RPN12 cDNA ORF clone, Saccharomyces cerevisiae S288C

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae.
Murakami Y, Naitou M, Hagiwara H, Shibata T, Ozawa M, Sasanuma S, Sasanuma M, Tsuchiya Y, Soeda E, Yokoyama K
Nature genetics10(3)261-8(1995 Jul)

Assimilation of the final lid subunit of the 26S proteasome, Rpn12, triggers a large-scale conformational remodeling of the nascent lid that drives regulatory particles assembly, in part by relieving steric clash with the base.
Title: A Single ? Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly.

Data show that proteasome subunits Rpt1, Rpt4, Rpn8, Rpn12, Pre6, and Pre10 are recruited to GAL10 rapidly upon galactose induction.
Title: Similar temporal and spatial recruitment of native 19S and 20S proteasome subunits to transcriptionally active chromatin.

Mass spectra of the intact lid complex from Saccharomyces cerevisiae show that eight of the nine subunits are present stoichiometrically and that a stable tetrameric subcomplex forms in solution.
Title: Structural organization of the 19S proteasome lid: insights from MS of intact complexes.

19S RP modulates SAGA complex using its ATPase components, thereby facilitating subsequent transcription events at promoters.
Title: The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.