Gene Symbol | STE50 |
Entrez Gene ID | 850325 |
Full Name | Ste50p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » STE50 cDNA ORF clone
Gene Symbol | STE50 |
Entrez Gene ID | 850325 |
Full Name | Ste50p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178677.1 | NP_009898.1 | Ste50p |
Eremothecium gossypii | AGOS_AFR706C | NP_986254.1 |
Kluyveromyces lactis | KLLA0C01386g | XP_452257.1 |
Saccharomyces cerevisiae (baker's yeast) | STE50 | NP_009898.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The complete DNA sequence of yeast chromosome III.
Oliver SG, van der Aart QJ, Agostoni-Carbone ML, Aigle M, Alberghina L, Alexandraki D, Antoine G, Anwar R, Ballesta JP, Benit P
Nature357(6373)38-46(1992 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Dynamic regulation of Ste50-Opy2 interaction fine-tunes the MAPK signaling network.
Title: Dynamic control of yeast MAP kinase network by induced association and dissociation between the Ste50 scaffold and the Opy2 membrane anchor.
Two peptide motifs within the intrinsically disordered cytoplasmic tail of Opy2p physically interact with the Step50p-RA domain.
Title: Binding the atypical RA domain of Ste50p to the unfolded Opy2p cytoplasmic tail is essential for the high-osmolarity glycerol pathway.
Ste50 has a role in control of MAPK specificity by feedback phosphorylation
Title: Control of MAPK specificity by feedback phosphorylation of shared adaptor protein Ste50.
inactivation of STE50 influences stress tolerance in mutants of the Ras-cAMP pathway, which is a major determinant of intrinsic stress tolerance and cell survival
Title: Ste50 adaptor protein influences Ras/cAMP-driven stress-response and cell survival in Saccharomyces cerevisiae.
propose that Opy2p can serve as a membrane anchor for the Ste50p/Ste11p module in the activation of the HOG pathway
Title: Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association.
The following STE50 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STE50 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00052 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178677.1 | |
Accession Version | NM_001178677.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Ste50p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001135). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAGGACG GTAAACAGGC CATCAATGAG GGATCAAACG ATGCTTCGCC GGATCTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009898.1 |
CDS | 1..1041 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGAGGACG GTAAACAGGC CATCAATGAG GGATCAAACG ATGCTTCGCC GGATCTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The complete DNA sequence of yeast chromosome III. |