Gene Symbol | hsk1 |
Entrez Gene ID | 2541165 |
Full Name | Dbf4(Dfp1)-dependent protein kinase Hsk1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » hsk1 cDNA ORF clone
Gene Symbol | hsk1 |
Entrez Gene ID | 2541165 |
Full Name | Dbf4(Dfp1)-dependent protein kinase Hsk1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001022249.2 | NP_596328.1 | Dbf4(Dfp1)-dependent protein kinase Hsk1 |
Drosophila melanogaster (fruit fly) | CG5790 | NP_609876.2 |
Saccharomyces cerevisiae (baker's yeast) | CDC7 | NP_010267.3 |
Eremothecium gossypii | AGOS_AER216C | NP_985073.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03488 | XP_003716435.1 |
Neurospora crassa | NCU11410 | XP_001728522.1 |
Kluyveromyces lactis | KLLA0C04345g | XP_452391.1 |
Schizosaccharomyces pombe (fission yeast) | hsk1 | NP_596328.1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
REVIEW: Hsk1/Cdc7, with its unique target specificity, can now be regarded as an important modulator of various chromosome transactions
Title: Regulation of chromosome dynamics by Hsk1/Cdc7 kinase.
Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation
Title: Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation.
Hsk1 kinase activity is required for induction and maintenance of Mrc1 hyperphosphorylation, which is induced by replication fork block and mediated by Rad3.
Title: Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast.
Hsk1-Dfp1 kinase functions post-initiation to maintain replication fork stability, an activity potentially mediated by the C terminus of Dfp1.
Title: Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.
propose that Hsk1 plays a vital role during post S phase in genome stability via SCF(Pof3)-mediated degradation of Ams2, thereby maintaining centromere integrity
Title: Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function.
The following hsk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hsk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc101108 | |
Clone ID Related Accession (Same CDS sequence) | NM_001022249.2 | |
Accession Version | NM_001022249.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | Dbf4(Dfp1)-dependent protein kinase Hsk1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003423). On Dec 10, 2012 this sequence version replaced NM_001022249.1. |
1 | ATGGCAGAGG CCCATATCAC ACTATCACCT AAAGTAACTC ATGAACAACA AACAGATATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_596328.1 |
CDS | 259..1782 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001022249.2 |
1 | ATGGCAGAGG CCCATATCAC ACTATCACCT AAAGTAACTC ATGAACAACA AACAGATATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |