Gene Symbol | MAVS |
Entrez Gene ID | 100037290 |
Full Name | mitochondrial antiviral signaling protein |
Synonyms | VISA |
Gene Type | protein-coding |
Organism | Sus scrofa(Pig) |
Genome |
ORF » Species Summary » Sus scrofa » MAVS cDNA ORF clone
Gene Symbol | MAVS |
Entrez Gene ID | 100037290 |
Full Name | mitochondrial antiviral signaling protein |
Synonyms | VISA |
Gene Type | protein-coding |
Organism | Sus scrofa(Pig) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_021077145.1 | XP_020932804.1 | mitochondrial antiviral-signaling protein isoform X2 |
NM_001097429.1 | NP_001090898.1 | mitochondrial antiviral-signaling protein |
XM_005672763.3 | XP_005672820.1 | mitochondrial antiviral-signaling protein isoform X1 |
XM_021077146.1 | XP_020932805.1 | mitochondrial antiviral-signaling protein isoform X3 |
XM_005672763.2 | XP_005672820.1 | mitochondrial antiviral-signaling protein isoform X1 |
Porcine reproductive and respiratory syndrome virus 3C protease cleaves the mitochondrial antiviral signalling complex to antagonize IFN-? expression.
Dong J, Xu S, Wang J, Luo R, Wang D, Xiao S, Fang L, Chen H, Jiang Y
The Journal of general virology96(10)3049-58(2015 Oct)
Mitochondrial antiviral signaling adaptor mediated apoptosis in H3N2 swine influenza virus infection is inhibited by viral protein NS1 in vitro.
Zhang J, Miao J, Hou J, Lu C
Veterinary immunology and immunopathology165(1-2)34-44(2015 May)
Molecular cloning and expression analysis of IFN-? promoter stimulator 1 in Tibetan pigs.
Zhao Y, Yu B, Mao X, Han G, Mao Q, Huang Z, Chen D
Molecular biology reports39(6)7011-7(2012 Jun)
Molecular cloning and functional characterization of porcine IFN-beta promoter stimulator 1 (IPS-1).
Wang D, Fang L, Li T, Luo R, Xie L, Jiang Y, Chen H, Xiao S
Veterinary immunology and immunopathology125(3-4)344-53(2008 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The authors determined that porcine reproductive and respiratory syndrome virus 3C protease cleaved MAVS at Glu268.
Title: Porcine reproductive and respiratory syndrome virus 3C protease cleaves the mitochondrial antiviral signalling complex to antagonize IFN-? expression.
upregulated at both the transcriptional and protein levels in the early stages of H3N2 infection
Title: Mitochondrial antiviral signaling adaptor mediated apoptosis in H3N2 swine influenza virus infection is inhibited by viral protein NS1 in vitro.
Real-time quantitative PCR analysis indicated that Tibetan porcine IPS-1 mRNA was most abundant in the liver and kidney.
Title: Molecular cloning and expression analysis of IFN-? promoter stimulator 1 in Tibetan pigs.
The following MAVS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAVS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe29286 | |
Clone ID Related Accession (Same CDS sequence) | NM_001097429.1 | |
Accession Version | NM_001097429.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-06-24 | |
Organism | Sus scrofa(pig) | |
Product | mitochondrial antiviral-signaling protein | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB287431.1. ##Evidence-Data-START## Transcript exon combination :: AB287431.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02389765, SAMN02584787 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGACGTTTG CCGAGGACAA GACTTATCAG TATATCCGCA ACCATCACAG GAATTTTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001090898.1 |
CDS | 1..1575 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001097429.1 |
1 | ATGACGTTTG CCGAGGACAA GACTTATCAG TATATCCGCA ACCATCACAG GAATTTTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe24755 | |
Clone ID Related Accession (Same CDS sequence) | XM_005672763.3 , XM_005672763.2 | |
Accession Version | XM_005672763.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-05-12 | |
Organism | Sus scrofa(pig) | |
Product | mitochondrial antiviral-signaling protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010459.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 13, 2017 this sequence version replaced XM_005672763.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACGTTTG CCGAGGACAA GACTTATCAG TATATCCGCA ACCATCACAG GAATTTTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005672820.1 |
CDS | 177..1751 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005672763.3 |
1 | ATGACGTTTG CCGAGGACAA GACTTATCAG TATATCCGCA ACCATCACAG GAATTTTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe24755 | |
Clone ID Related Accession (Same CDS sequence) | XM_005672763.3 , XM_005672763.2 | |
Accession Version | XM_005672763.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-10 | |
Organism | Sus scrofa(Pig) | |
Product | mitochondrial antiviral-signaling protein isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003612552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005672763.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACGTTTG CCGAGGACAA GACTTATCAG TATATCCGCA ACCATCACAG GAATTTTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005672820.1 |
CDS | 178..1752 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005672763.2 |
1 | ATGACGTTTG CCGAGGACAA GACTTATCAG TATATCCGCA ACCATCACAG GAATTTTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe240851 | |
Clone ID Related Accession (Same CDS sequence) | XM_021077145.1 | |
Accession Version | XM_021077145.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-05-12 | |
Organism | Sus scrofa(pig) | |
Product | mitochondrial antiviral-signaling protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010459.5) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTCTGGA GATTCTGCCT TACCTGTCCT GCCTCACAGC AAGTGACCAG CCTTCGGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_020932804.1 |
CDS | 244..1686 |
Translation |
Target ORF information:
Target ORF information:
|
XM_021077145.1 |
1 | ATGTTCTGGA GATTCTGCCT TACCTGTCCT GCCTCACAGC AAGTGACCAG CCTTCGGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe240852 | |
Clone ID Related Accession (Same CDS sequence) | XM_021077146.1 | |
Accession Version | XM_021077146.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-05-12 | |
Organism | Sus scrofa(pig) | |
Product | mitochondrial antiviral-signaling protein isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010459.5) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTACAG AGAGGATGAG CCAAGTTACC CCATGCCTGT CCAGGATACC CAGTCGCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_020932805.1 |
CDS | 503..1858 |
Translation |
Target ORF information:
Target ORF information:
|
XM_021077146.1 |
1 | ATGGCTACAG AGAGGATGAG CCAAGTTACC CCATGCCTGT CCAGGATACC CAGTCGCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Porcine reproductive and respiratory syndrome virus 3C protease cleaves the mitochondrial antiviral signalling complex to antagonize IFN-? expression. |
Mitochondrial antiviral signaling adaptor mediated apoptosis in H3N2 swine influenza virus infection is inhibited by viral protein NS1 in vitro. |
Molecular cloning and expression analysis of IFN-? promoter stimulator 1 in Tibetan pigs. |
Molecular cloning and functional characterization of porcine IFN-beta promoter stimulator 1 (IPS-1). |