Gene Symbol | GCN4 |
Entrez Gene ID | 856709 |
Full Name | amino acid starvation-responsive transcription factor GCN4 |
Synonyms | AAS101,AAS3,ARG9 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » GCN4 cDNA ORF clone
Gene Symbol | GCN4 |
Entrez Gene ID | 856709 |
Full Name | amino acid starvation-responsive transcription factor GCN4 |
Synonyms | AAS101,AAS3,ARG9 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178824.3 | NP_010907.3 | amino acid starvation-responsive transcription factor GCN4 |
Kluyveromyces lactis | KLLA0D14113g | XP_453692.1 |
Saccharomyces cerevisiae (baker's yeast) | GCN4 | NP_010907.3 |
Eremothecium gossypii | AGOS_ADL012C | NP_984085.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The down-regulation of the GCN4 expression (Gcn(-) phenotype) in the eIF5(G31R) mutant was not because of leaky scanning defects; rather was due to the utilization of upUUG initiation codons at the 5' regulatory region present between uORF1 and the main GCN4 ORF.
Title: Defect in the GTPase activating protein (GAP) function of eIF5 causes repression of GCN4 translation.
Presented are molecular dynamics simulations reflecting a secondary structure of phopspho-GCN4 at different pH.
Title: Nuclear Magnetic Resonance Structures of GCN4p Are Largely Conserved When Ion Pairs Are Disrupted at Acidic pH but Show a Relaxation of the Coiled Coil Superhelix.
GCN4 is required for the elevated life spans of nup100-null mutants, similar to other previously described tRNA export and ribosomal mutants.
Title: Nup100 regulates
GCN4 is required for nitrogen catabolite repression-sensitive nuclear Gln3 localization.
Title: General Amino Acid Control and 14-3-3 Proteins Bmh1/2 Are Required for Nitrogen Catabolite Repression-Sensitive Regulation of Gln3 and Gat1 Localization.
SCH9 deletion causes the upregulation of many amino acid biosynthesis pathways and increases glycerol during fermentation. When Gcn4p was overexpressed during winemaking, increased glycerol production was also observed.
Title: Sch9p kinase and the Gcn4p transcription factor regulate glycerol production during winemaking.
The following GCN4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GCN4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05479 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178824.3 | |
Accession Version | NM_001178824.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | amino acid starvation-responsive transcription factor GCN4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). On Jul 30, 2012 this sequence version replaced NM_001178824.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCCGAAT ATCAGCCAAG TTTATTTGCT TTAAATCCAA TGGGTTTCTC ACCATTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010907.3 |
CDS | 1..846 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178824.3 |
1 | ATGTCCGAAT ATCAGCCAAG TTTATTTGCT TTAAATCCAA TGGGTTTCTC ACCATTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |