Gene Symbol | TAP42 |
Entrez Gene ID | 855043 |
Full Name | Tap42p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » TAP42 cDNA ORF clone
Gene Symbol | TAP42 |
Entrez Gene ID | 855043 |
Full Name | Tap42p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182524.1 | NP_013741.1 | Tap42p |
Kluyveromyces lactis | KLLA0C12793g | XP_452770.1 |
Arabidopsis thaliana (thale cress) | TAP46 | NP_568783.1 |
Saccharomyces cerevisiae (baker's yeast) | TAP42 | NP_013741.1 |
Schizosaccharomyces pombe (fission yeast) | SPCC63.05 | NP_587979.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01540 | XP_003714514.1 |
Neurospora crassa | NCU08268 | XP_961896.1 |
Oryza sativa (rice) | Os11g0141000 | NP_001065714.1 |
Oryza sativa (rice) | Os12g0137500 | NP_001066109.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that Tec1 protein stability is under control of the nutrient-sensitive target of rapamycin complex 1 (TORC1) signaling pathway via the Tip41-Tap42-Sit4 branch.
Title: The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development.
These data support a model in which autophagy is negatively regulated by the Tap42-PP2A pathway.
Title: Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy.
Tap42 functions in the same positive direction as Sit4, Pph21 and Pph22 in Ty1 transcriptional silencing, providing support to the idea that Tap42 may play a positive role in phosphatase activity in response to TORC1 signalling
Title: An essential role of Tap42-associated PP2A and 2A-like phosphatases in Ty1 transcriptional silencing of S. cerevisiae.
Here, we describe the crystal structure of the PP2Ac-interaction domain of Saccharomyces cerevisiae Tap42. The structure reveals an all alpha-helical protein with striking similarity to 14-3-3 and tetratricopeptide repeat (TPR) proteins.
Title: The structure of Tap42/alpha4 reveals a tetratricopeptide repeat-like fold and provides insights into PP2A regulation.
These findings suggest that the association of the Tap42-phosphatase complexes with TORC1 represents an important mechanism by which nutrient controls Tor signaling activity.
Title: Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1.
The following TAP42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAP42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04027 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182524.1 | |
Accession Version | NM_001182524.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Tap42p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCGTCAG TAACAGAACA ATTCAACGAT ATTATTAGCT TATACTCAAC AAAATTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013741.1 |
CDS | 1..1101 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182524.1 |
1 | ATGGCGTCAG TAACAGAACA ATTCAACGAT ATTATTAGCT TATACTCAAC AAAATTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |