Gene Symbol | POB3 |
Entrez Gene ID | 854933 |
Full Name | FACT complex subunit POB3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » POB3 cDNA ORF clone
Gene Symbol | POB3 |
Entrez Gene ID | 854933 |
Full Name | FACT complex subunit POB3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182428.1 | NP_013642.1 | FACT complex subunit POB3 |
Saccharomyces cerevisiae (baker's yeast) | POB3 | NP_013642.1 |
Eremothecium gossypii | AGOS_AER138C | NP_984997.1 |
Danio rerio (zebrafish) | ssrp1a | NP_997967.1 |
Kluyveromyces lactis | KLLA0B04906g | XP_451752.1 |
Neurospora crassa | NCU11168 | XP_956186.1 |
Schizosaccharomyces pombe (fission yeast) | pob3 | NP_596315.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_14751 | XP_003713777.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
FACT binding results in dramatic ATP-independent, symmetrical and reversible DNA uncoiling that affects at least 70% of the DNA within a nucleosome. Nucleosome unfolding by yFACT (Spt16-Pob3 with Nhp6) is extensive and reversible.
Title: Large-scale ATP-independent nucleosome unfolding by a histone chaperone.
FACT remodels the tetranucleosomal unit of chromatin fibers for gene transcription.
Title: FACT Remodels the Tetranucleosomal Unit of Chromatin Fibers for Gene Transcription.
Histone chaperones FACT and Spt6 are important for appropriate H2AZ histone localization and for the functioning of RNA polymerase II.
Title: Histone chaperones FACT and Spt6 prevent histone variants from turning into histone deviants.
Spt6 and FACT have both overlapping and distinct functional interactions with histones and nucleosomes and that binding to each of the components of a nucleosome is not sufficient to produce nucleosome reorganization
Title: The Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae.
FACT, a heterodimer of Spt16 and Pob3, disrupts nucleosome structure by binding H2A-H2B with conserved peptide motifs.
Title: FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs.
The following POB3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POB3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03932 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182428.1 | |
Accession Version | NM_001182428.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1659bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | FACT complex subunit POB3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGTACCG ACTTTGATAG AATTTACTTG AACCAATCTA AATTTAGCGG TAGATTCCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013642.1 |
CDS | 1..1659 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182428.1 |
1 | ATGAGTACCG ACTTTGATAG AATTTACTTG AACCAATCTA AATTTAGCGG TAGATTCCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |