Gene Symbol | EXO70 |
Entrez Gene ID | 853359 |
Full Name | GTP-Rho binding exocyst subunit EXO70 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » EXO70 cDNA ORF clone
Gene Symbol | EXO70 |
Entrez Gene ID | 853359 |
Full Name | GTP-Rho binding exocyst subunit EXO70 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181518.1 | NP_012450.1 | GTP-Rho binding exocyst subunit EXO70 |
Eremothecium gossypii | AGOS_AFR100W | NP_985647.1 |
Saccharomyces cerevisiae (baker's yeast) | EXO70 | NP_012450.1 |
Neurospora crassa | NCU08012 | XP_962682.2 |
Kluyveromyces lactis | KLLA0F14421g | XP_455728.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01760 | XP_003714759.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat JC, Coster F, Cziepluch C, De Haan M, Domdey H, Durand P, Entian KD, Gatius M, Goffeau A, Grivell LA, Hennemann A, Herbert CJ, Heumann K, Hilger F, Hollenberg CP, Huang ME, Jacq C, Jauniaux JC, Katsoulou C, Karpfinger-Hartl L
The EMBO journal15(9)2031-49(1996 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate structural details of the interaction of exocyst complex Sec3p and Exo70p with lipid bilayers containing phosphatidylinositol (4,5)-bisphosphate (PIP2) by molecular dynamics simulations.
Title: Membrane targeting of the yeast exocyst complex.
Exo70p directly and specifically binds to the polarity determinant scaffold protein Bem1p. The interaction involves multiple domains of both Exo70p and Bem1p.
Title: Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p.
Data show that Exo70 has the biochemical properties expected of a direct effector for both Rho3 and Cdc42, and suggest that interaction with the Exo70 component of the exocyst is a key event in spatial regulation of exocytosis by Rho GTPases.
Title: The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis.
The results suggest that either Exo70p or Sec3p must associate with the plasma membrane for the exocyst to function as a vesicle tether.
Title: An internal domain of Exo70p is required for actin-independent localization and mediates assembly of specific exocyst components.
Exo70 mediates the assembly of the exocyst complex at the plasma membrane, which is a crucial step in the tethering of post-Golgi secretory vesicles for exocytosis.
Title: Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane.
The following EXO70 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EXO70 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02627 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181518.1 | |
Accession Version | NM_001181518.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | GTP-Rho binding exocyst subunit EXO70 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001142). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCCGCTG AAATTGACAT TGATGAAGCT GACGTATTAG TTTTATCACA GGAGTTACAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012450.1 |
CDS | 1..1872 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181518.1 |
1 | ATGCCCGCTG AAATTGACAT TGATGAAGCT GACGTATTAG TTTTATCACA GGAGTTACAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. |