Gene Symbol | TRL1 |
Entrez Gene ID | 853358 |
Full Name | tRNA ligase |
Synonyms | LIG1,RLG1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » TRL1 cDNA ORF clone
Gene Symbol | TRL1 |
Entrez Gene ID | 853358 |
Full Name | tRNA ligase |
Synonyms | LIG1,RLG1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181520.1 | NP_012448.1 | tRNA ligase |
Neurospora crassa | NCU04410 | XP_957487.1 |
Kluyveromyces lactis | KLLA0F14399g | XP_455727.1 |
Eremothecium gossypii | AGOS_AFR099C | NP_985646.2 |
Schizosaccharomyces pombe (fission yeast) | trl1 | NP_593724.2 |
Saccharomyces cerevisiae (baker's yeast) | TRL1 | NP_012448.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_05169 | XP_003712706.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat JC, Coster F, Cziepluch C, De Haan M, Domdey H, Durand P, Entian KD, Gatius M, Goffeau A, Grivell LA, Hennemann A, Herbert CJ, Heumann K, Hilger F, Hollenberg CP, Huang ME, Jacq C, Jauniaux JC, Katsoulou C, Karpfinger-Hartl L
The EMBO journal15(9)2031-49(1996 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Findings suggest for the tRNA ligase (Trl1) as an antifungal target.
Title: Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase.
the mechanism for intron turnover requires healing of the 5' termini of linear introns by the tRNA ligase Rlg1 and destruction by the cytoplasmic tRNA quality control 5'-to-3' exonuclease Xrn1, which has specificity for RNAs with 5' monophosphate
Title: Healing for destruction: tRNA intron degradation in yeast is a two-step cytoplasmic process catalyzed by tRNA ligase Rlg1 and 5'-to-3' exonuclease Xrn1.
These results suggest that RNA ligase Trl1 for tRNA splicing might therefore commonly function as an RNA ligase for XBP1 mRNA splicing.
Title: Function of yeast and amphioxus tRNA ligase in IRE1alpha-dependent XBP1 mRNA splicing.
Structural requirements for the C-terminal 5'-kinase/2',3'-cyclic phosphodiesterase domain for Trl1 enzyme activity.
Title: Structure-function analysis of the kinase-CPD domain of yeast tRNA ligase (Trl1) and requirements for complementation of tRNA splicing by a plant Trl1 homolog.
Four essential residues Lys114, Glu184, Glu266, and Lys284 important for the structure and function of tRNA ligase were clarified.
Title: Structure-function analysis of yeast tRNA ligase.
The following TRL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02626 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181520.1 | |
Accession Version | NM_001181520.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2484bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | tRNA ligase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001142). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCTAGCC CATATGACGG TAAAAGAACA GTAACTCAGC TTGTTAACGA GTTAGAAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012448.1 |
CDS | 1..2484 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181520.1 |
1 | ATGCCTAGCC CATATGACGG TAAAAGAACA GTAACTCAGC TTGTTAACGA GTTAGAAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. |