Gene Symbol | RAD30 |
Entrez Gene ID | 852028 |
Full Name | DNA-directed DNA polymerase eta |
Synonyms | DBH1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RAD30 cDNA ORF clone
Gene Symbol | RAD30 |
Entrez Gene ID | 852028 |
Full Name | DNA-directed DNA polymerase eta |
Synonyms | DBH1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180727.3 | NP_010707.3 | DNA-directed DNA polymerase eta |
Saccharomyces cerevisiae (baker's yeast) | RAD30 | NP_010707.3 |
Kluyveromyces lactis | KLLA0A01848g | XP_451081.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Profiles of base-substitutions created by Polzeta & Poleta of Saccharomyces cerevisiae were analyzed. Poleta created deletions at the lesion in more than 50% of the TLS products, but the formation of the deletions was suppressed by the presence of Polzeta. Polzeta & Poleta cooperatively facilitated the TLS reaction over an abasic site in vitro, suggesting that these two polymerases can cooperate in efficient and high f...
Title: NGS-based analysis of base-substitution signatures created by yeast DNA polymerase eta and zeta on undamaged and abasic DNA templates in vitro.
This study provides further understanding of the mutation mechanism of alkylated lesion for yeast DNA polymerase eta.
Title: Kinetic analysis of bypass of O(6)- methylguanine by the catalytic core of yeast DNA polymerase eta.
These data indicate that under certain conditions, pol eta can compete with the cell's replicases and gain access to undamaged genomic DNA.
Title: Unlocking the steric gate of DNA polymerase ? leads to increased genomic instability in Saccharomyces cerevisiae.
This study provides further understanding in the mutation mechanism of abasic sites for yeast DNA polymerase eta
Title: Kinetic analysis of bypass of abasic site by the catalytic core of yeast DNA polymerase eta.
The stability of Pol eta, but not its mRNA level, is cell cycle stage dependent. The half-life of the polymerase is more than fourfold shorter in G1-arrested cells than in those at G2/M.
Title: The steady-state level and stability of TLS polymerase eta are cell cycle dependent in the yeast S. cerevisiae.
The following RAD30 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAD30 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01495 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180727.3 | |
Accession Version | NM_001180727.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1899bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | DNA-directed DNA polymerase eta | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). On Jul 30, 2012 this sequence version replaced NM_001180727.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCAAAAT TTACTTGGAA GGAGTTGATT CAGCTTGGTT CCCCCAGTAA AGCATACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010707.3 |
CDS | 1..1899 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180727.3 |
1 | ATGTCAAAAT TTACTTGGAA GGAGTTGATT CAGCTTGGTT CCCCCAGTAA AGCATACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |