Gene Symbol | PPH3 |
Entrez Gene ID | 851647 |
Full Name | phosphoprotein phosphatase PP4 catalytic subunit PPH3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » PPH3 cDNA ORF clone
Gene Symbol | PPH3 |
Entrez Gene ID | 851647 |
Full Name | phosphoprotein phosphatase PP4 catalytic subunit PPH3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180383.1 | NP_010360.1 | phosphoprotein phosphatase PP4 catalytic subunit PPH3 |
PPP4C | XP_001108500.1 | |
Canis lupus familiaris (dog) | PPP4C | XP_547067.1 |
Rattus norvegicus (Norway rat) | Ppp4c | NP_599186.1 |
Danio rerio (zebrafish) | ppp4cb | NP_001104638.1 |
Kluyveromyces lactis | KLLA0E10055g | XP_454403.1 |
Drosophila melanogaster (fruit fly) | Pp4-19C | NP_524803.1 |
Neurospora crassa | NCU08301 | XP_962514.2 |
Arabidopsis thaliana (thale cress) | PPX1 | NP_194402.1 |
Oryza sativa (rice) | Os09g0284200 | NP_001062774.1 |
Pan troglodytes (chimpanzee) | PPP4C | XP_001148577.1 |
Eremothecium gossypii | AGOS_AGR136W | NP_986802.2 |
Schizosaccharomyces pombe (fission yeast) | SPBC26H8.05c | NP_596646.1 |
Xenopus tropicalis (tropical clawed frog) | ppp4c | NP_988943.1 |
Bos taurus (cattle) | PPP4C | NP_001092578.1 |
Mus musculus (house mouse) | Ppp4c | NP_062648.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003779 | XP_310323.5 |
Caenorhabditis elegans (roundworm) | pph-4.1 | NP_499603.1 |
Homo sapiens (human) | PPP4C | NP_002711.1 |
Saccharomyces cerevisiae (baker's yeast) | PPH3 | NP_010360.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01528 | XP_003714501.1 |
Arabidopsis thaliana (thale cress) | PPX2 | NP_200337.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Physical interaction between Pph3 and Mec1, mediated by cofactors Psy2 and Ddc2, is important for regulating the checkpoint response in yeast.
Title: Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.
Data show that Pph3-Psy2 targets the glucose signal transducer protein Mth1, which is required for the dephosphorylation of Rgt1 upon glucose withdrawal, a critical event in the repression of HXT genes, which encode glucose transporters.
Title: Psy2 targets the PP4 family phosphatase Pph3 to dephosphorylate Mth1 and repress glucose transporter gene expression.
Data indicate that the phosphatase complex Pph3/Psy2 connects homologous end-joining (NHEJ) repair to cell cycle progression.
Title: Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae.
Results suggest that the trimeric Pph3p-Psy4p-Psy2p complex may dephosphorylate both gammaH2AX and Rad53p.
Title: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage.
Mutational analyses of conserved regions of Tap42/alpha4 identified a region critical for its interactions with PP2Ac. We propose a scaffolding function for Tap42/alpha4 whereby the interaction of PP2Ac promotes the dephosphorylation of substrates.
Title: The structure of Tap42/alpha4 reveals a tetratricopeptide repeat-like fold and provides insights into PP2A regulation.
The following PPH3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PPH3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01164 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180383.1 | |
Accession Version | NM_001180383.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | phosphoprotein phosphatase PP4 catalytic subunit PPH3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGATGGACT TAGATAAGAT TATAGCATCA CTGAGAGACG GAAAACATAT TCCTGAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010360.1 |
CDS | 1..927 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180383.1 |
1 | ATGATGGACT TAGATAAGAT TATAGCATCA CTGAGAGACG GAAAACATAT TCCTGAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |