SOD2 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene
Clones
gRNAs

Summary

Gene Symbol	SOD2
Entrez Gene ID	856399
Full Name	superoxide dismutase SOD2
Gene Type	protein-coding
Organism	Saccharomyces cerevisiae S288C

mRNA and Protein(s)

mRNA	Protein	Name
NM_001179138.1	NP_011872.1	superoxide dismutase SOD2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SOD2	XP_533463.3
Anopheles gambiae (African malaria mosquito)	MNSOD1	XP_314490.4
Caenorhabditis elegans (roundworm)	sod-3	NP_510764.1
Eremothecium gossypii	AGOS_ADR160W	NP_984257.2
Magnaporthe oryzae (rice blast fungus)	MGG_00212	XP_003718898.1
Bos taurus (cattle)	SOD2	NP_963285.2
Gallus gallus (chicken)	SOD2	NP_989542.1
Caenorhabditis elegans (roundworm)	sod-2	NP_492290.1
Neurospora crassa	NCU09560	XP_959485.1
Oryza sativa (rice)	Os05g0323900	NP_001055195.1
Homo sapiens (human)	SOD2	NP_000627.2
Danio rerio (zebrafish)	sod2	NP_956270.1
Drosophila melanogaster (fruit fly)	Sod2	NP_476925.1
Saccharomyces cerevisiae (baker's yeast)	SOD2	NP_011872.1
Kluyveromyces lactis	KLLA0E03609g	XP_454107.1
Xenopus tropicalis (tropical clawed frog)	sod2	NP_001005694.1
Pan troglodytes (chimpanzee)	SOD2	NP_001009022.1
	SOD2	NP_001027977.1
Mus musculus (house mouse)	Sod2	NP_038699.2
Rattus norvegicus (Norway rat)	Sod2	NP_058747.1
Schizosaccharomyces pombe (fission yeast)	SPAC1486.01	NP_594089.1
Arabidopsis thaliana (thale cress)	MSD1	NP_187703.1

Gene Ontology
Bibliography

Related articles in PubMed

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Johnston M, Andrews S, Brinkman R, Cooper J, Ding H, Dover J, Du Z, Favello A, Fulton L, Gattung S
Science (New York, N.Y.)265(5181)2077-82(1994 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results provide evidence that the mutation I91T brings damage to Sod2 activity, con fi rming further the role of the yeast S. cerevisiae as a model to study disease mechanisms related to oxidative stress.
Title: In Vivo Characterization of I91T Sod2 Polymorphism of Saccharomyces cerevisiae.

Repression of SOD2 prevents ethanol-induced relocalization of yeast hydrogen peroxide-sensing transcription factor Yap1p, one of the key stress resistance proteins. Analysis of the ethanol sensitivities of the cells lacking Sod2p, Yap1p, or both indicated that the two proteins act in the same pathway.
Title: Mitochondrial Superoxide Dismutase and Yap1p Act as a Signaling Module Contributing to Ethanol Tolerance of the Yeast Saccharomyces cerevisiae.

surface-potential distribution of SOD2 revealed a conserved positively charged electrostatic zone in the proximity of the active site
Title: Structures of native and Fe-substituted SOD2 from Saccharomyces cerevisiae.

Data find that misincorporation of iron into yeast Sod2p does not correlate with significant changes in the average oxidation state or coordination chemistry of bulk mitochondrial iron.
Title: The interaction of mitochondrial iron with manganese superoxide dismutase.

Inactivation of SOD1 and SOD2 modifies response to S-nitrosoglutathione-induced stress.
Title: Inactivation of genes encoding superoxide dismutase modifies yeast response to S-nitrosoglutathione-induced stress.

The following SOD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SOD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSi05205	NM_001179138.1 Latest version!	Saccharomyces cerevisiae S288C superoxide dismutase SOD2 (SOD2), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SOD2 ( NM_001179138.1 ) cDNA ORF clone, Saccharomyces cerevisiae S288C -> NP_011872.1 Saccharomyces cerevisiae S288C superoxide dismutase SOD2 (SOD2), partial mRNA.

Price & Availability↑

CloneID	OSi05205
Clone ID Related Accession (Same CDS sequence)	NM_001179138.1
Accession Version	NM_001179138.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-31
Organism	Saccharomyces cerevisiae S288C
Product	superoxide dismutase SOD2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001140). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Veresion :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends.

ATGTTCGCGA AAACAGCAGC TGCTAATTTA ACCAAGAAGG GTGGTTTGTC ATTGCTCTCC 
ACCACAGCAA GGAGAACCAA AGTCACCTTG CCAGACTTGA AGTGGGACTT CGGTGCATTG 
GAACCTTATA TCTCCGGTCA AATCAACGAA TTGCATTACA CCAAGCACCA TCAAACTTAT 
GTGAACGGAT TCAACACTGC TGTTGACCAA TTCCAAGAAC TCTCAGATCT TCTGGCCAAG 
GAGCCCTCTC CCGCAAACGC AAGAAAAATG ATTGCTATCC AACAAAACAT CAAGTTCCAT 
GGCGGTGGTT TCACAAACCA CTGTCTATTC TGGGAAAACC TGGCTCCAGA GTCGCAGGGC 
GGTGGTGAAC CACCCACCGG CGCTTTGGCA AAGGCAATCG ACGAGCAGTT TGGCAGTCTG 
GACGAGCTGA TTAAGTTGAC CAACACAAAG CTAGCAGGCG TGCAGGGCTC CGGATGGGCC 
TTCATTGTGA AAAACCTCTC TAATGGAGGC AAGCTGGACG TTGTTCAAAC CTACAACCAG 
GATACCGTCA CAGGCCCACT AGTTCCTCTA GTTGCCATTG ACGCCTGGGA ACACGCCTAC 
TACTTGCAGT ACCAAAACAA GAAAGCCGAC TACTTCAAAG CCATTTGGAA TGTGGTCAAC 
TGGAAAGAAG CATCCAGAAG ATTCGATGCT GGCAAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_011872.1
CDS	1..702
Translation	MFAKTAAANLTKKGGLSLLSTTARRTKVTLPDLKWDFGALEPYISGQINELHYTKHHQTYVNGFNTAVDQFQELSDLLAKEPSPANARKMIAIQQNIKFHGGGFTNHCLFWENLAPESQGGGEPPTGALAKAIDEQFGSLDELIKLTNTKLAGVQGSGWAFIVKNLSNGGKLDVVQTYNQDTVTGPLVPLVAIDAWEHAYYLQYQNKKADYFKAIWNVVNWKEASRRFDAGKI

Target ORF information:

RefSeq Version	NM_001179138.1
Organism	Saccharomyces cerevisiae S288C
Definition	Saccharomyces cerevisiae S288C superoxide dismutase SOD2 (SOD2), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001179138.1

ORF Insert Sequence:

ATGTTCGCGA AAACAGCAGC TGCTAATTTA ACCAAGAAGG GTGGTTTGTC ATTGCTCTCC 
ACCACAGCAA GGAGAACCAA AGTCACCTTG CCAGACTTGA AGTGGGACTT CGGTGCATTG 
GAACCTTATA TCTCCGGTCA AATCAACGAA TTGCATTACA CCAAGCACCA TCAAACTTAT 
GTGAACGGAT TCAACACTGC TGTTGACCAA TTCCAAGAAC TCTCAGATCT TCTGGCCAAG 
GAGCCCTCTC CCGCAAACGC AAGAAAAATG ATTGCTATCC AACAAAACAT CAAGTTCCAT 
GGCGGTGGTT TCACAAACCA CTGTCTATTC TGGGAAAACC TGGCTCCAGA GTCGCAGGGC 
GGTGGTGAAC CACCCACCGG CGCTTTGGCA AAGGCAATCG ACGAGCAGTT TGGCAGTCTG 
GACGAGCTGA TTAAGTTGAC CAACACAAAG CTAGCAGGCG TGCAGGGCTC CGGATGGGCC 
TTCATTGTGA AAAACCTCTC TAATGGAGGC AAGCTGGACG TTGTTCAAAC CTACAACCAG 
GATACCGTCA CAGGCCCACT AGTTCCTCTA GTTGCCATTG ACGCCTGGGA ACACGCCTAC 
TACTTGCAGT ACCAAAACAA GAAAGCCGAC TACTTCAAAG CCATTTGGAA TGTGGTCAAC 
TGGAAAGAAG CATCCAGAAG ATTCGATGCT GGCAAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Life with 6000 genes.
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Goffeau A,Barrell BG,Bussey H,Davis RW,Dujon B,Feldmann H,Galibert F,Hoheisel JD,Jacq C,Johnston M,Louis EJ,Mewes HW,Murakami Y,Philippsen P,Tettelin H,Oliver SG

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Science (New York, N.Y.)265(5181)2077-82(1994 Sep)
Johnston M,Andrews S,Brinkman R,Cooper J,Ding H,Dover J,Du Z,Favello A,Fulton L,Gattung S

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SOD2 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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