Gene Symbol | ERG6 |
Entrez Gene ID | 855003 |
Full Name | sterol 24-C-methyltransferase |
Synonyms | ISE1,LIS1,SED6,VID1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » ERG6 cDNA ORF clone
Gene Symbol | ERG6 |
Entrez Gene ID | 855003 |
Full Name | sterol 24-C-methyltransferase |
Synonyms | ISE1,LIS1,SED6,VID1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182363.1 | NP_013706.1 | sterol 24-C-methyltransferase |
Eremothecium gossypii | AGOS_ADR196W | NP_984292.1 |
Saccharomyces cerevisiae (baker's yeast) | ERG6 | NP_013706.1 |
Kluyveromyces lactis | KLLA0A01738g | XP_451076.1 |
Schizosaccharomyces pombe (fission yeast) | erg6 | NP_595787.1 |
Neurospora crassa | NCU03006 | XP_965392.1 |
Oryza sativa (rice) | Os07g0206700 | NP_001059154.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_10568 | XP_003721384.1 |
Arabidopsis thaliana (thale cress) | SMT1 | NP_196875.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Lis1 has two opposing modes of regulating dynein, being capable of inducing both low and high affinity for the microtubule; study shows that these opposing modes depend on the stoichiometry of Lis1 binding to dynein and that this stoichiometry is regulated by the nucleotide state of dynein's AAA3 domain.
Title: Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.
Data show that the erg6Delta mutant strain is more sensitive to hyperosmotic shocks than is WT.
Title: Nature of sterols affects plasma membrane behavior and yeast survival during dehydration.
In the K6R substituted Hmg2 mutant, the squalene content was approximately 20-fold higher than in the wild-type EGY48 parental strain and ERG6 deletion did not further enhance squalene accumulation.
Title: Observations on squalene accumulation in Saccharomyces cerevisiae due to the manipulation of HMG2 and ERG6.
Overexpression of ERG6 and ERG2 led to an increased ergosterol level.
Title: [Regulation role of sterol C-24 methyltransferase and sterol C-8 isomerase in the ergosterol biosynthesis of Saccharomyces cerevisiae].
photolabeling & mutagenesis were performed on 24-C-sterol methyltransferase to elucidate location & role of active site residues involved in AdoMet binding & catalysis; results indicate that one or both of Cys128 & Pro133 are covalently bound to AdoMet
Title: Photoaffinity labeling and mutational analysis of 24-C-sterol methyltransferase defines the AdoMet binding site.
The following ERG6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERG6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03992 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182363.1 | |
Accession Version | NM_001182363.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | sterol 24-C-methyltransferase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGTGAAA CAGAATTGAG AAAAAGACAG GCCCAATTCA CTAGGGAGTT ACATGGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013706.1 |
CDS | 1..1152 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182363.1 |
1 | ATGAGTGAAA CAGAATTGAG AAAAAGACAG GCCCAATTCA CTAGGGAGTT ACATGGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |