Gene Symbol | CYB2 |
Entrez Gene ID | 854950 |
Full Name | Cyb2p |
Synonyms | FCB2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CYB2 cDNA ORF clone
Gene Symbol | CYB2 |
Entrez Gene ID | 854950 |
Full Name | Cyb2p |
Synonyms | FCB2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182412.1 | NP_013658.1 | L-lactate dehydrogenase (cytochrome) |
Magnaporthe oryzae (rice blast fungus) | MGG_01723 | XP_003714720.1 |
Xenopus tropicalis (tropical clawed frog) | hao2 | NP_001025624.1 |
Homo sapiens (human) | HAO2 | NP_001005783.1 |
Bos taurus (cattle) | HAO2 | NP_001030243.1 |
Arabidopsis thaliana (thale cress) | AT3G14130 | NP_188029.1 |
Oryza sativa (rice) | Os07g0616500 | NP_001060276.1 |
Canis lupus familiaris (dog) | HAO2 | XP_533023.3 |
Gallus gallus (chicken) | HAO2 | XP_416535.4 |
Neurospora crassa | NCU08272 | XP_961900.1 |
Arabidopsis thaliana (thale cress) | AT3G14150 | NP_001078152.1 |
Mus musculus (house mouse) | Hao2 | NP_062418.3 |
Rattus norvegicus (Norway rat) | Hao2 | NP_114471.1 |
Kluyveromyces lactis | KLLA0D02640g | XP_453186.1 |
Pan troglodytes (chimpanzee) | HAO2 | XP_003308337.1 |
HAO2 | XP_001113689.2 | |
Danio rerio (zebrafish) | hao2 | NP_956777.1 |
Saccharomyces cerevisiae (baker's yeast) | CYB2 | NP_013658.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The present results support the idea that the heme domain mobility is an inherent component of the Fcb2 functioning.
Title: Structural evidence for the functional importance of the heme domain mobility in flavocytochrome b2.
Disruption of the CYB2 gene encoding L-lactate dehydrogenase improved the L-lactate production by S. cerevisiae under low pH condition.
Title: Improvement of L-lactate production by CYB2 gene disruption in a recombinant Saccharomyces cerevisiae strain under low pH condition.
separately engineered flavodehydrogenase domain produces superoxide anion in its slow reaction with oxygen. This reaction also takes place in the holoenzyme when oxygen is the sole electron acceptor, because the heme domain autoxidation is also slow.
Title: Flavocytochrome b2: reactivity of its flavin with molecular oxygen.
The combination of an altered active site and the small kinetic isotope effects is consistent with the slowest step in turnover being a conformational change involving a conformation in which lactate is bound unproductively.
Title: Mechanistic and structural studies of H373Q flavocytochrome b2: effects of mutating the active site base.
The following CYB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03948 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182412.1 | |
Accession Version | NM_001182412.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | L-lactate dehydrogenase (cytochrome) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCTAAAAT ACAAACCTTT ACTAAAAATC TCGAAGAACT GTGAGGCTGC TATCCTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013658.1 |
CDS | 1..1776 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182412.1 |
1 | ATGCTAAAAT ACAAACCTTT ACTAAAAATC TCGAAGAACT GTGAGGCTGC TATCCTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |