Gene Symbol | EXO1 |
Entrez Gene ID | 854198 |
Full Name | Rad2 family nuclease EXO1 |
Synonyms | DHS1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » EXO1 cDNA ORF clone
Gene Symbol | EXO1 |
Entrez Gene ID | 854198 |
Full Name | Rad2 family nuclease EXO1 |
Synonyms | DHS1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183452.1 | NP_014676.1 | Rad2 family nuclease EXO1 |
Kluyveromyces lactis | KLLA0E16743g | XP_454705.1 |
Eremothecium gossypii | AGOS_AER387C | NP_985242.2 |
Saccharomyces cerevisiae (baker's yeast) | EXO1 | NP_014676.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Npl3 participates in DNA double-strand break resection by promoting the proper biogenesis of EXO1 mRNA.
Title: The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1.
the mechanisms of DNA end resection in Saccharomyces cerevisiae, which includes short-range resection by Mre11-Rad50-Xrs2 and Sae2, as well as processive long-range resection by Sgs1-Dna2 or Exo1 pathways.
Title: DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination.
Exo1-dependent and independent mismatch repair has been described. (Review)
Title: Exonuclease 1-dependent and independent mismatch repair.
RPA could exclude Ku from a partially resected structure with a 22-nt ssDNA tail and thus restored processing by Exo1. However, at a 40-nt tail, Ku remained stably associated at the ssDNA-dsDNA junction, and RPA simultaneously engaged the ssDNA region.
Title: Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection.
Models for the functional interactions of mitotic cyclin Clb2, Sgs1 and Exo1 with replication fork stabilization are proposed.
Title: The analysis of S. cerevisiae cells deleted for mitotic cyclin Clb2 reveals a novel requirement of Sgs1 DNA helicase and Exonuclease 1 when replication forks break in the presence of alkylation damage.
The following EXO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EXO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03345 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183452.1 | |
Accession Version | NM_001183452.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2109bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Rad2 family nuclease EXO1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGTATCC AAGGTCTTCT TCCTCAGTTA AAGCCCATAC AGAATCCAGT ATCACTACGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014676.1 |
CDS | 1..2109 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183452.1 |
1 | ATGGGTATCC AAGGTCTTCT TCCTCAGTTA AAGCCCATAC AGAATCCAGT ATCACTACGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |