Gene Symbol | TRZ1 |
Entrez Gene ID | 853954 |
Full Name | tRNase Z |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » TRZ1 cDNA ORF clone
Gene Symbol | TRZ1 |
Entrez Gene ID | 853954 |
Full Name | tRNase Z |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179869.1 | NP_013005.1 | tRNase Z |
Kluyveromyces lactis | KLLA0F16665g | XP_455829.1 |
Neurospora crassa | NCU00232 | XP_957703.1 |
Saccharomyces cerevisiae (baker's yeast) | TRZ1 | NP_013005.1 |
Eremothecium gossypii | AGOS_ADR212C | NP_984308.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_05303 | XP_003712864.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome XI.
Dujon B, Alexandraki D, Andr? B, Ansorge W, Baladron V, Ballesta JP, Banrevi A, Bolle PA, Bolotin-Fukuhara M, Bossier P, Bou G, Boyer J, Bultrago MJ, Cheret G, Colleaux L, Dalgnan-Fornler B, del Rey F, Dlon C, Domdey H, D?sterhoft A, D?sterhus S, Entlan KD, Erfle H, Esteban PF, Feldmann H, Fernandes L, Robo GM, Fritz C, Fukuhara H, Gabel C, Gaillon L, Carcia-Cantalejo JM, Garcia-Ramirez JJ, Gent NE, Ghazvini M, Goffeau A, Gonzal?z A, Grothues D, Guerreiro P, Hegemann J, Hewitt N, Hilger F, Hollenberg CP, Horaitis O, Indge KJ, Jacquier A, James CM, Jauniaux C, Jimenez A, Keuchel H, Kirchrath L, Kleine K, K?tter P, Legrain P, Liebl S, Louis EJ, Maia e Silva A, Marck C, Monnier AL, M?stl D, M?ller S, Obermaier B, Oliver SG, Pallier C, Pascolo S, Pfeiffer F, Philippsen P, Planta RJ, Pohl FM, Pohl TM, P?hlmann R, Portetelle D, Purnelle B, Puzos V, Ramezani Rad M, Rasmussen SW, Remacha M, Revuelta JL, Richard GF, Rieger M, Rodrigues-Pousada C, Rose M, Rupp T, Santos MA, Schwager C, Sensen C, Skala J, Soares H, Sor F, Stegemann J, Tettelin H, Thierry A, Tzermia M, Urrestarazu LA, van Dyck L, Van Vliet-Reedijk JC, Valens M, Vandenbo M, Vilela C, Vissers S, von Wettstein D, Voss H, Wiemann S, Xu G, Zimmermann J, Haasemann M, Becker I, Mewes HW
Nature369(6479)371-8(1994 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The 3.1 A crystal structure of the long-form Trz1 from Saccharomyces cerevisiae shows Trz1 is organized into 2 beta-lactamase domains connected by a long linker. The N-terminal domain has lost its catalytic residues, but keeps the long flexible arm important for tRNA binding, but it is the opposite in the C-terminal domain. Trz1 likely evolved from a duplication and fusion of the gene for the monomeric short form RNase Z.
Title: The crystal structure of Trz1, the long form RNase Z from yeast.
The yeast tRNA 3' endonuclease tRNase Z, Trz1, is catalyzing endonucleolytic tRNA 3' processing.
Title: tRNA 3' processing in yeast involves tRNase Z, Rex1, and Rrp6.
The findings reveal that 3' end processing is a limiting step for defective tRNA maturation and demonstrate that overexpression of scTRZ1 can promote defective tRNA 3' processing in vivo.
Title: Functional conservation of tRNase ZL among Saccharomyces cerevisiae, Schizosaccharomyces pombe and humans.
AthTRZ1 shows a high affinity for Zn2+ ions
Title: Metal requirements and phosphodiesterase activity of tRNase Z enzymes.
In this work, we show that the yeast homolog of ELAC2, encoded by TRZ1 (tRNase Z 1), is involved genetically in RNA processing.
Title: Characterization of TRZ1, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNase Z.
The following TRZ1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRZ1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03131 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179869.1 | |
Accession Version | NM_001179869.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2517bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | tRNase Z | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001143). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTTCACAT TTATACCCAT CACCCATCCT ACATCGGATA CAAAGCACCC ATTGCTGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013005.1 |
CDS | 1..2517 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179869.1 |
1 | ATGTTCACAT TTATACCCAT CACCCATCCT ACATCGGATA CAAAGCACCC ATTGCTGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome XI. |