Gene Symbol | TIF1 |
Entrez Gene ID | 853933 |
Full Name | translation initiation factor eIF4A |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » TIF1 cDNA ORF clone
Gene Symbol | TIF1 |
Entrez Gene ID | 853933 |
Full Name | translation initiation factor eIF4A |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179849.3 | NP_012985.3 | translation initiation factor eIF4A |
Pan troglodytes (chimpanzee) | EIF4A1 | NP_001092045.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC1006.07 | NP_594854.1 |
Neurospora crassa | NCU07420 | XP_958421.2 |
Arabidopsis thaliana (thale cress) | AT1G72730 | NP_177417.1 |
Saccharomyces cerevisiae (baker's yeast) | TIF2 | NP_012397.1 |
Eremothecium gossypii | AGOS_ACR253C | NP_983655.1 |
Danio rerio (zebrafish) | eif4a1b | NP_958918.1 |
Saccharomyces cerevisiae (baker's yeast) | TIF1 | NP_012985.3 |
Xenopus tropicalis (tropical clawed frog) | eif4a1 | NP_001011139.1 |
EIF4A1 | XP_001085678.1 | |
Bos taurus (cattle) | EIF4A1 | NP_001029400.1 |
Mus musculus (house mouse) | Eif4a1 | NP_659207.1 |
Rattus norvegicus (Norway rat) | Eif4a1 | NP_955404.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_04400 | XP_003711015.1 |
Homo sapiens (human) | EIF4A1 | NP_001407.1 |
Canis lupus familiaris (dog) | EIF4A1 | NP_001238871.1 |
Danio rerio (zebrafish) | eif4a1a | NP_938180.1 |
Kluyveromyces lactis | KLLA0A05731g | XP_451255.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome XI.
Dujon B, Alexandraki D, Andr? B, Ansorge W, Baladron V, Ballesta JP, Banrevi A, Bolle PA, Bolotin-Fukuhara M, Bossier P, Bou G, Boyer J, Bultrago MJ, Cheret G, Colleaux L, Dalgnan-Fornler B, del Rey F, Dlon C, Domdey H, D?sterhoft A, D?sterhus S, Entlan KD, Erfle H, Esteban PF, Feldmann H, Fernandes L, Robo GM, Fritz C, Fukuhara H, Gabel C, Gaillon L, Carcia-Cantalejo JM, Garcia-Ramirez JJ, Gent NE, Ghazvini M, Goffeau A, Gonzal?z A, Grothues D, Guerreiro P, Hegemann J, Hewitt N, Hilger F, Hollenberg CP, Horaitis O, Indge KJ, Jacquier A, James CM, Jauniaux C, Jimenez A, Keuchel H, Kirchrath L, Kleine K, K?tter P, Legrain P, Liebl S, Louis EJ, Maia e Silva A, Marck C, Monnier AL, M?stl D, M?ller S, Obermaier B, Oliver SG, Pallier C, Pascolo S, Pfeiffer F, Philippsen P, Planta RJ, Pohl FM, Pohl TM, P?hlmann R, Portetelle D, Purnelle B, Puzos V, Ramezani Rad M, Rasmussen SW, Remacha M, Revuelta JL, Richard GF, Rieger M, Rodrigues-Pousada C, Rose M, Rupp T, Santos MA, Schwager C, Sensen C, Skala J, Soares H, Sor F, Stegemann J, Tettelin H, Thierry A, Tzermia M, Urrestarazu LA, van Dyck L, Van Vliet-Reedijk JC, Valens M, Vandenbo M, Vilela C, Vissers S, von Wettstein D, Voss H, Wiemann S, Xu G, Zimmermann J, Haasemann M, Becker I, Mewes HW
Nature369(6479)371-8(1994 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results reveal and characterize an unexpected interdependence between the two RNA helicases and eIF4G, and suggest that Ded1p is an integral part of eIF4F, the complex comprising eIF4G, eIF4A, and eIF4E.
Title: Coupling between the DEAD-box RNA helicases Ded1p and eIF4A.
Findings suggest that Ded1 is critically required to promote scanning through secondary structures within 5' UTRs, and while eIF4A cooperates with Ded1 in this function, it also promotes a step of initiation common to virtually all yeast mRNAs.
Title: Genome-wide analysis of translational efficiency reveals distinct but overlapping functions of yeast DEAD-box RNA helicases Ded1 and eIF4A.
Yeast eIF4B strongly promotes productive interaction of eIF4A with the 43S*mRNA pre-initiation complex (PIC) in a manner required for efficient mRNA recruitment.
Title: Yeast eIF4B binds to the head of the 40S ribosomal subunit and promotes mRNA recruitment through its N-terminal and internal repeat domains.
Glucose depletion inhibits translation initiation via eukaryotic initiation factor 4a loss and subsequent 48S preinitiation complex accumulation
Title: Glucose depletion inhibits translation initiation via eIF4A loss and subsequent 48S preinitiation complex accumulation, while the pentose phosphate pathway is coordinately up-regulated.
structure of the complex formed by yeast eIF4G's middle domain and full-length eIF4A at 2.6-A resolution
Title: Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions.
The following TIF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TIF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03112 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179849.3 | |
Accession Version | NM_001179849.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | translation initiation factor eIF4A | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001143). On Jul 30, 2012 this sequence version replaced NM_001179849.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTGAAG GTATTACTGA TATTGAAGAA TCCCAAATTC AAACCAACTA TGACAAGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012985.3 |
CDS | 1..1188 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179849.3 |
1 | ATGTCTGAAG GTATTACTGA TATTGAAGAA TCCCAAATTC AAACCAACTA TGACAAGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome XI. |