Gene Symbol | BTN2 |
Entrez Gene ID | 853043 |
Full Name | Btn2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » BTN2 cDNA ORF clone
Gene Symbol | BTN2 |
Entrez Gene ID | 853043 |
Full Name | Btn2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181271.3 | NP_011658.3 | Btn2p |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Juxtanuclear deposits of misfolded protein reside in an intranuclear quality control compartment whose formation is dependent on Btn2.
Title: Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition.
Normal levels of the antiprion proteins Btn2 and Cur1 cure most newly formed [URE3] prion variants.
Title: Normal levels of the antiprion proteins Btn2 and Cur1 cure most newly formed [URE3] prion variants.
Protein redistribution by Btn2 is accompanied by a gradual depletion of Sis1 from the cytosol, which is mediated by the sorting factor Cur1.
Title: Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates.
Btn2-mediated endosomal protein trafficking and prion curing in yeast is regulated by Btn3
Title: Btn3 is a negative regulator of Btn2-mediated endosomal protein trafficking and prion curing in yeast.
Btn2p is part of a system that collects aggregates preventing their efficient distribution to progeny cells
Title: Curing of the [URE3] prion by Btn2p, a Batten disease-related protein.
The following BTN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BTN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02365 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181271.3 | |
Accession Version | NM_001181271.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Btn2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). On Jul 30, 2012 this sequence version replaced NM_001181271.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTTTTCCA TATTCAATTC ACCATGTGTT TTTGAACAGC TGCCATCTTT TAGTCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011658.3 |
CDS | 1..1233 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181271.3 |
1 | ATGTTTTCCA TATTCAATTC ACCATGTGTT TTTGAACAGC TGCCATCTTT TAGTCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |