Gene Symbol | CDC28 |
Entrez Gene ID | 852457 |
Full Name | cyclin-dependent serine/threonine-protein kinase CDC28 |
Synonyms | CDK1,HSL5,SRM5 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CDC28 cDNA ORF clone
Gene Symbol | CDC28 |
Entrez Gene ID | 852457 |
Full Name | cyclin-dependent serine/threonine-protein kinase CDC28 |
Synonyms | CDK1,HSL5,SRM5 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178508.3 | NP_009718.3 | cyclin-dependent serine/threonine-protein kinase CDC28 |
Pan troglodytes (chimpanzee) | CDK2 | XP_003952210.1 |
Neurospora crassa | NCU09778 | XP_960117.1 |
Saccharomyces cerevisiae (baker's yeast) | CDC28 | NP_009718.3 |
Oryza sativa (rice) | Os03g0118400 | NP_001048772.1 |
Bos taurus (cattle) | CDK2 | NP_001014934.1 |
Mus musculus (house mouse) | Cdk2 | NP_904326.1 |
Rattus norvegicus (Norway rat) | Cdk2 | NP_955795.1 |
Drosophila melanogaster (fruit fly) | cdc2c | NP_732544.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004579 | XP_562342.4 |
Kluyveromyces lactis | KLLA0B09790g | XP_451964.1 |
Eremothecium gossypii | AGOS_ADR058C | NP_984154.1 |
Schizosaccharomyces pombe (fission yeast) | cdc2 | NP_595629.1 |
Arabidopsis thaliana (thale cress) | CDC2 | NP_566911.1 |
Xenopus tropicalis (tropical clawed frog) | cdk2 | NP_001008136.1 |
Homo sapiens (human) | CDK2 | NP_001789.2 |
CDK2 | XP_001113345.1 | |
Canis lupus familiaris (dog) | CDK2 | XP_005625536.1 |
Gallus gallus (chicken) | CDK2 | NP_001186786.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01362 | XP_003714294.1 |
Danio rerio (zebrafish) | cdk2 | NP_998571.1 |
Oryza sativa (rice) | Os02g0123100 | NP_001045731.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome II.
Feldmann H, Aigle M, Aljinovic G, Andr? B, Baclet MC, Barthe C, Baur A, B?cam AM, Biteau N, Boles E, Brandt T, Brendel M, Br?ckner M, Bussereau F, Christiansen C, Contreras R, Crouzet M, Cziepluch C, D?molis N, Delaveau T, Doignon F, Domdey H, D?sterhus S, Dubois E, Dujon B, El Bakkoury M, Entian KD, Feurmann M, Fiers W, Fobo GM, Fritz C, Gassenhuber H, Glandsdorff N, Goffeau A, Grivell LA, de Haan M, Hein C, Herbert CJ, Hollenberg CP, Holmstr?m K, Jacq C, Jacquet M, Jauniaux JC, Jonniaux JL, Kalles?e T, Kiesau P, Kirchrath L, K?tter P, Korol S, Liebl S, Logghe M, Lohan AJ, Louis EJ, Li ZY, Maat MJ, Mallet L, Mannhaupt G, Messenguy F, Miosga T, Molemans F, M?ller S, Nasr F, Obermaier B, Perea J, Pi?rard A, Piravandi E, Pohl FM, Pohl TM, Potier S, Proft M, Purnelle B, Ramezani Rad M, Rieger M, Rose M, Schaaff-Gerstenschl?ger I, Scherens B, Schwarzlose C, Skala J, Slonimski PP, Smits PH, Souciet JL, Steensma HY, Stucka R, Urrestarazu A, van der Aart QJ, van Dyck L, Vassarotti A, Vetter I, Vierendeels F, Vissers S, Wagner G, de Wergifosse P, Wolfe KH, Zagulski M, Zimmermann FK, Mewes HW, Kleine K
The EMBO journal13(24)5795-809(1994 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study reports a novel Cdk1-interacting protein, YPL014W, named Cip1 (for Cdk1-interacting protein 1); results show that Cip1 specifically interacts with G1 /S-phase Cln2-Cdk1 complex but not with S-phase Clb5-Cdk1 or M-phase Clb2-Cdk1 complexes.
Title: Identification of YPL014W (Cip1) as a novel negative regulator of cyclin-dependent kinase in Saccharomyces cerevisiae.
the G1/S transition, Cdk1 phosphorylates and activates the enzyme Nth1, which funnels the storage carbohydrate trehalose into central carbon metabolism. Trehalose utilization fuels anabolic processes required to reliably complete cell division.
Title: The Yeast Cyclin-Dependent Kinase Routes Carbon Fluxes to Fuel Cell Cycle Progression.
Co-regulation of cell division processes and metabolic processes by CDK activity may be a general phenomenon important for co-ordinating the cell cycle with growth in S.cerevisiae.
Title: Cyclin-Dependent Kinase Co-Ordinates Carbohydrate Metabolism and Cell Cycle in S.?cerevisiae.
Whi5 phosphorylation by Cln3-Cdk1 embedded in the G1/S network dynamically controls critical cell size and cell fate.
Title: Whi5 phosphorylation embedded in the G1/S network dynamically controls critical cell size and cell fate.
Cdk1 and multiple cyclins become highly enriched at DSBs and that the recruitment of Cdk1 and cyclins Clb2 and Clb5 ensures optimal Fun30 phosphorylation and checkpoint activation.
Title: Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection.
The following CDC28 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC28 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01862 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178508.3 | |
Accession Version | NM_001178508.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | cyclin-dependent serine/threonine-protein kinase CDC28 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001134). On Jul 30, 2012 this sequence version replaced NM_001178508.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGCGGTG AATTAGCAAA TTACAAAAGA CTTGAGAAAG TCGGTGAAGG TACATACGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009718.3 |
CDS | 1..897 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178508.3 |
1 | ATGAGCGGTG AATTAGCAAA TTACAAAAGA CTTGAGAAAG TCGGTGAAGG TACATACGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome II. |